Antenatal Care Flashcards
what dose of folic acid should be given pre-conception?
400mg
folic acid 400mg should be given from before conception until __ weeks
12
which patients should receive a higher dose of folic acid from 12 weeks gestation?
- BMI >30
- individuals with diabetes
- individuals on antiepileptics
- individuals with a previous pregnancy affected by a neural tube defect
the booking visit should be done between _ and _ weeks
week 10-12
a fetal anomaly scan is done between _ and _ weeks
18-20+6
the first stage of trisomy screening is done between _ and _ weeks
11-13+6 weeks
what does the ultrasound scan look for when we screen for down’s syndrome?
nuchal translucency
a normal value for nuchal translucency is
<3.5mm
the second stage of trisomy screening (quadruple blood test) is done at _ to _ weeks
15-16 weeks
what 4 pregnancy hormones are measured in the quadruple test?
AFP
hCG
unconjugated estriol
inhibin A
the first stage of trisomy screening involves…
a blood test
an USS
what hormones are checked in the combined test for downs syndrome?
PAPP-A
AFP
bHCG
PAPP-A and AFP levels will be ___ if the fetus has downs syndrome
low
when do women get their first USS in pregnancy
10-13+6 weeks at the booking visit
what does the booking USS look for?
- viability
- determines gestation
- confirms intrauterine pregnancy
- number of pregnancies
when is symphyseal fundal height first measured?
24 weeks
when is an OGTT offered to check for gestational diabetes
28 weeks
women with preexisting diabetes or women with new gestational diabetes are offered extra scans between _ and _ weeks
28-36 weeks
when mothers are first exposed to the rhesus antigen they form Ig__ antibodies which are too big to cross the placenta and harm the fetus
IgM
when mothers are exposed to the rhesus antigen for a second time the body forms Ig_ antibodies which are smaller and can cross the placenta and harm the fetus
IgG
how does anti-D work?
removes Rh positive blood cells from the mother’s circulation before antibodies are formed
when is anti-D given
to rhesus NEGATIVE mothers who have been exposed to a sensitising event
name a sensitising event that would require use of anti-D in a Rh -ve mother
- vaginal bleeding from 12 weeks
- TOP
- amniocentesis/CVS
- surgical management of miscarriage
- molar pregnancy
- ectopic pregnancy
- delivery if baby is Rh +ve
- fetal death
how long does a dose of anti-D last?
6 weeks
will cover further sensitising events in this period
when is prophylactic anti-D given to Rh -ve mothers and why?
28 weeks
to cover silent sensitising events
when is diagnostic testing such as CVS and amniocentesis offered to women?
if they are:
A. found to be at high risk of downs syndrome at trisomy screening
B. fetal anomaly seen at 20 week scan
which can be done before 15 weeks: CVS or amniocentesis?
CVS
can be done from 11-13+6 weeks
if twins are referred to as monochorionic diamniotic this means…
they share a placenta but not an amniotic sac
AFP is ___ in multiple pregnancy
high
how regularly are women seen who have confirmed monochorionic twins on scan?
every 2 weeks by a consultant
how regularly are women seen who have confirmed dichorionic twins on scan?
every 4 weeks
what supplementation are women with multiple pregnancy given?
iron
folic acid
low dose aspirin
when should DCDA twins be delivered?
37-38 weeks
when should MCDA twins be delivered? what precautionary management should be given?
36+0 weeks with steroids