Antagonistas de Canales de Calcio Flashcards

1
Q

Nifedipina: Nombre comercial

A

ADALAT

TENSOPIN

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2
Q

Nifedipina: Presentacion

A

Adalat: capsulas 10mg
Tensopin: Comprimidos 10mg

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3
Q

Nifedipina: Dosis

A

Minima: 30mg/OD
Maxima: 120mg/OD

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4
Q

Nifedipina: Vida media

A

1,5 - 5 horas

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5
Q

Nifedipina: Mecanismo de Accion

A

Inhiben selectivamente los canales de calcio dependiente de voltaje tipo L en el tejido miocárdico, de arterias coronarias y vasos periféricos

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6
Q

Nifedipina: Efectos adversos

A
  • Cefalea
  • Enrojecimiento facial
  • Edema bimaleolar
  • Insuficiencia cardíaca
  • Bradicardia
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7
Q

Nifedipina: Interacciones

A

Nifedipina con
ADO: Disminuye el efecto hipoglucemiante

Aumenta efecto antihipertensivo por:
      -  Cimetidina
      - Ranitidina
      - Bloqueadores ß
adrenérgicos
      - Anti-arrítmicos
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8
Q

Amlodipina: Nombre comercial

A

DILOTEX

AMLOPIN

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9
Q

Amlodipina: Presentacion

A

Comprimidos

5mg - 10 mg

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10
Q

Amlodipina: Dosis min y max

A

Dosis minima: 5mg/dia

Dosis maxima: 10mg/dia

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11
Q

Amlodipina: Vida media

A

35 - 50 horas

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12
Q

Amlodipina: MEcanismo de accion

A

Inhiben selectivamente los canales de calcio dependiente de voltaje tipo L en el tejido miocárdico, de arterias coronarias y vasos periféricos

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13
Q

Amlodipina: Efectos adversos

A
  • Cefalea
  • Enrojecimiento facial
  • Edema bimaleolar
  • Insuficiencia cardíaca
  • Bradicardia
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14
Q

Amlodipina: Interacciones

A
Aumenta efecto antihipertensivo por:
      -  Cimetidina
      - Ranitidina
      - Bloqueadores ß
adrenérgicos
      - Anti-arrítmicos
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15
Q

Nimodipina: nombre comercial

A

NIMOTOP

BRAINAL

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16
Q

Nimodipina: presentacion

A

Nimotop: comprimidos 30mg
Brainal: 10mg/50ml

17
Q

Nimodipina: dosis min y max

A

Minima: 120mg/dia
Maxima: 360 mg/dia

18
Q

Nimodipina: Vida media

A

5 - 10 horas

19
Q

Nimodipina: mecanismo de accion

A

Inhiben selectivamente los canales de calcio dependiente de voltaje tipo L en el tejido miocárdico, de arterias coronarias y vasos periféricos

20
Q

Nimodipina: Efectos adversos

A
  • Cefalea
  • Enrojecimiento facial
  • Edema bimaleolar
  • Insuficiencia cardíaca
  • Bradicardia
  • Vasoespasmo rebote (Exclusivo de Nimodipina)
21
Q

Nimodipina: interacciones medicamentosas

A

Fenobarbital, fenitoina y carbamacepina: disminuyen niveles séricos

B-Bloqueantes: Causan depresión de la contractilidad cardiaca