Ans Receptors Flashcards

1
Q

M1

A

Nerve endings; Gq - increase IP3 and DAG

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2
Q

M2

A

Heart; Gi - decrease cAMP and activates potassium channels

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3
Q

M3

A

Smooth muscle, gands, endothelium; Gq - increase IP3 and DAG

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4
Q

Nn

A

ANS ganglia; deplarizes through sodium potassium channel

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5
Q

Nm

A

Neurmuscular end plate; depolarizes through sodium postassium channel

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6
Q

Alpha1

A

smooth muscle, gands; Gq - increase IP3 and DAG; increase calcium - causes contraction or secretion

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7
Q

Alpha2

A

nerve endings; Gi - decrease cAMP; decreases transmitter release

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8
Q

Beta1

A

cardiac muscle, juxtaglomerular apparatus; Gs - increase cAMP increase heart rate and force, increases renin release

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9
Q

Beta2

A

smooth muscle, liver, heart; Gs - increases cAMP; relax smooth muscle. Increase glycogenolysis, increases heart rate and force

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10
Q

Beta3

A

Adipose cells; Gs - increase cAMP; increase lipolysis

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11
Q

Dopamine1

A

Smooth muscle; Gs - increase cAMP; relax renal vascular smooth muscle

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12
Q

Alpha 1 targets

A

mydriasis (contracts radial muscle); contracts splanchnic and skeletal muscle vessels; contracts GI and genitourinary sphincters; contracts uterus; causes ejaculation; contracts pilomotor smooth muscle; increases apocrine secretion; gluconeogenesis ang glycogenolysis

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13
Q

Beta1 targets

A

relaxes ciliary muscles; accelerates SA node; accelerates ectopic pacemakers; increases contractility; stimulates renin release

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14
Q

Beta2 targets

A

relaxes ciliary muscles; accelerates SA node; accelerates ectopic pacemakers; increases contractility; relaxes skeletal muscle vessels; relaxes GI smooth muscle; relaxes bronciolar smooth muscle; relaxes bladder wall; relaxes uterus; gluconeogenesis; glycogenolysis

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15
Q

M1 targets

A

activates myenteric plexus; erection

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16
Q

M2 targets

A

decelerates SA node; decreases atrial contractility; erection

17
Q

M3 targets

A

myosis (contracts circular muscle); accomodation (relaxes ciliary muscle); contracts bronchiolar smooth muscle; contracts GI smooth muscle; relaxes GI and genitourinary sphincters; increases GI secretion; contracts bladder; contacts uterus; erection