ANS Pharmacology

Question 1

The cranial parasympathetic nerve includes….

Answer 1

3 7 9 12

Question 2

Muscarine is derived from a poisonous mushroom called ………………

Answer 2

Amanita muscaria

Question 3

What is the vesicular proteoglycan

Answer 3

The VPG is the protein which acetylcholine binds in the vessicle

Question 4

Acetylcholine is stored together with …………… …………. in the vesicle

Answer 4

Peptide P
ATP
Vesicular proteoglycan

Question 5

Two diuretics works dependent on the basis of production of prostaglandin

Answer 5

Loop diuretics but not so important
Potassium sparing diuretics *** important

Question 6

List three sympathomimmetics

Answer 6

Amphetamine,tyramine, ephedrine

Question 7

Some indirect cholinomimmetics have direct functions like ……………… which inhibits muscular nicotinic receptor

Answer 7

Neostigmine

Question 8

The B methyl groups of the choline esters( methacolin and bethanecol) reduces their potency for ……………..

Answer 8

Nicotinic receptor

Question 9

The alkaloids are …………. and excreted through ………….. and their excretion is promoted by ……….

Answer 9

Amines
Kidney
Acidification

Question 10

The lipid soluble indirect cholinomimetics are ……………. structure of amine while non lipid synthetic are …………

Answer 10

Tertiary
Quaternary

Question 11

All organophosphate cholinomimetics are readily lipid soluble except ………

Answer 11

Echotiophate, polar and more stable