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Pharmacology > ANS Drugs > Flashcards

ANS Drugs Flashcards

1
Q

What are the indicications for Clonidine and Dexmedetodine?

A

HTN
Severe pain
ADHD

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2
Q

What are the indications for phentolamine (non selective alpha antagonist)?

A

For HTN emergencies, pehochromocytoma, infiltration (to counterbalance NE)

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3
Q

What is the indication for prazosin (A1 >a2)?

A

BPH, HTN

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4
Q

What is the effect and indications of isoproterenol?

A

“Chemical pacemaker!” - increases HR, increases contractility, bronchodilation
Indications: heart block or pacemaker to elicit tachycardia in surgery

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5
Q

What are the indications for dobutamine (b1 > b2)?

A

Good for patients with CHF

Increases contractility w/o increasing HR or BP!

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6
Q

What are side effects of terbutaline and albuterol?

A

Tremore, hyokalemia, hyperglycemia in diabetics

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7
Q

What beta antagonist would you give to an asthmatic?

A

Metropolol (B1 selective) - would not cause vasoconstriction of the lungs

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8
Q

What are the indications for atenolol?

A

Patients with CAD

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9
Q

Which beta blocker is not used for HTN?

A

Esmolol (B1 selective) - used for emergency IV therapy of tachycardia

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10
Q

What are the indications for propranolol (B1 = B2)?

A

HTN, angina, cardiac dysrhytmias, MI

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11
Q

What are the 2 synthetic catecholamines?

A

Dobutamine and isoproterenol

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12
Q

What are the effects/indications of bethanechol?

A

Used for decreased GI/GU motility (post -op)

Effects include increased secretions and peristalsis, decreased HR, increase tone and motility of GI, bladder emptying

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13
Q

When would you not give bethanechol?

A

Patients with heart block, bladder or bowel obstruction, asthma, or hypotension

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14
Q

What muscarinic antagonist would give for muscarinic poisoning or cholingeric crisis?

A

Atropine

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15
Q

Why would you not give atropine to an asthmatic?

A

Can thicken and dry up secretions

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16
Q

What is ipatropium (muscarinic antagonist) indicated for?

A

Bronchodilation for asthmatics and COPD patients

17
Q

What are the two acetylcholinterase inhibitors?

A

Pyridostigmine and Neostigmine

18
Q

What are the indications for pyridostigmine?

A

Can reverse nondepolarizing muscle relaxants

Used for glaucoma, myasthenia gravis and NMB reversal

19
Q

What are the side effects of succhinycholase?

A

Hyperkalemia/muscle pain

20
Q

What is a non depolarizing muscle relaxant and what are the effects?

A

Roncuronium —> complete paralysis but patient can feel pain and is not sedated

21
Q

What is the antidote to acetaminophen overdose?

A

Acetylcysteine - can convert toxic metabolite

22
Q

What is ephedrine and what are the effects

A

Indirect acting non catecholamine
Increases concentration of NE by blocking reuptake
Can cross BBB

Pharmacology (6 decks)

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