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Pharmacology > ANS Drug Effects > Flashcards

ANS Drug Effects Flashcards

1
Q

PNS agonist effect on heart

A

decrease in heart rate, contractility, and conduction

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2
Q

PNS agonist effect on blood vessels

A

vasodilation

not PNS innervated

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3
Q

PNS agonist effect on blood pressure

A

decreased blood pressure

adverse: hypotension

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4
Q

PNS agonist effect on lung

A

bronchoconstriction

adverse: increased secretions

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5
Q

PNS agonist effect on eye

A

miosis, accomodation (near vision), increased aqueous humor outflow
treats glaucoma

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6
Q

PNS agonist effect on GI/GU

A

increased salivation, detrusor contraction, and motility
treats xerostomia and improves urinary flow
adverse: diarrhea

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7
Q

PNS agonist effect on NMJ

A

muscle contraction

treats myasthenia gravis

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8
Q

PNS agonist effect on CNS

A

memory, cognition, movement

treats alzheimers

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9
Q

PNS antagonist effect on heart

A

increased heart rate

treats bradycardia

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10
Q

PNS antagonist effect on blood vessels

A

no effect; no basal M tone to antagonize

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11
Q

PNS antagonist effect on blood pressure

A

minimal effect

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12
Q

PNS antagonist effect on lung

A

bronchodilation

adverse: increased drying

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13
Q

PNS antagonist effect on eye

A

mydriasis

adverse: blurred vision, decreased outflow, exacerbates glaucoma

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14
Q

PNS antagonist effect on GI/GU

A

decreases salivation, blocks detruser, motility
used to create a dry field, treats overactive bladder and diarrhea
adverse: dry mouth, urinary hesitancy/retention, constipation

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15
Q

PNS antagonist effect on NMJ

A

flaccid paralysis

used in surgery as a muscle relaxer

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16
Q

PNS antagonist effect on CNS

A

treats parkinsons, anti-emetic

adverse: sedation, confusion

17
Q

SNS agonist effect on heart

A

beta-1: increases heart rate and contractility
treats cardiogenic shock
adverse: pro-arrythmic, precipitates angina

18
Q

SNS agonist effect on blood vessels

A

alpha-1: vasoconstriction
treats hypotensive shock, decongestant
adverse: hypertension
beta-2: vasodilation

19
Q

SNS agonist effect on blood pressure

A

alpha-1 and beta-1: increases blood pressure
treats hypotensive shock
beta-2: decreases blood pressure
adverse: hypotension if unopposed by alpha-1

20
Q

SNS agonist effect on lung

A

beta-2: bronchodilation

treats asthma

21
Q

SNS agonist effect on eye

A

alpha-1: mydriasis
used during eye exams
betas: increased humor production

22
Q

SNS agonist effect on GI/GU

A 
alpha-2: GI relaxation via decreased ACh release
beta-2,3: smooth muscle relaxation 
treats overactive bladder
alpha-1: close sphincter 
promotes continence 
beta-2: uterine relaxation 
treats premature labor
23
Q

SNS agonist effect on NMJ

A

beta-2 causes muscle tremors

24
Q

SNS agonist effect on CNS

A

increases vigilance and focus

treats ADHD

25
Q

SNS antagonist effect on heart

A

beta-1: decreases heart rate and contractility
treats hypertension, angina, arrhythmias, CHF
adverse: bradycardia, heart block

26
Q

SNS antagonist effect on blood vessels

A

alpha-1: vasodilation
treats hypertension
beta-2 adverse: vasoconstriction, decreased perfusion

27
Q

SNS antagonist effect on blood pressure

A

alpha-1 and beta-1: decreased blood pressure
treats hypertension
alpha-2 agonist: decreases blood pressure
treats hypertension
adverse: dry mouth, sedation

28
Q

SNS antagonist effect on lung

A

beta-2: bronchospasm

29
Q

SNS antagonist effect on eye

A

beta-1,2: decreased aqueous humor production, decreased intraocular pressure
treats glaucoma

30
Q

SNS antagonist effect on GI/GU

A

alpha-1: open sphincter

treats micturition disorders and BPH

31
Q

SNS antagonist effect on CNS

A

betas treat stage fright, essential tremor

adverse: depressed mood, sleep disturbances

Pharmacology (6 decks)

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