ANS

Question 1

Pilocarpine

Answer 1

DOC for acute glaucoma attack.

Cholinergic medication : lacrimation ( outflow of fluids )

Question 2

Pysostigmine, neostigmine, edrophonium

Answer 2

All block ACH cholinesterase
Anticholinesterase drugs

Increase ach in cleft : cholinergic drug

Question 3

Bethanochol ( urecholine )
Pilocarpine

Answer 3

Direct cholinergic agonists

Question 4

Atropine

Answer 4

Tx of symptomatic bradycardia ( can interchange with epinephrine)

CHOLINERGIC ANTAGONIST

Question 5

Scopolamine

Answer 5

Cholinergic antagonists

Question 6

Epinephrine

Answer 6

Activates B1, b2 a1 but NOT alpha 2

Comes IM IV SC ( NO ORAL )

At low doses mostly B1, B2 , at high doses mostly alpha 1

Question 7

First measure in treating any type of shock is go give?

Answer 7

Volume resuscitation by IV NS ( 0.9%)

Question 8

DOC of hypovolemic shock

Answer 8

NE or DA

This is shock due to low circulatory volume due to blood loss , dehydration

DA has renal vasodilatory effect but also causes more arrhythmias than NE

Question 9

Cardiogenic shock

Answer 9

Due to MI/HF leading left ventricle pump failure

Dobutamine ( B1 ) strong ionotrope DOC and B2

Can use other vasopressors instead of dobutamine when it’s not available

Question 10

Septic shock

Answer 10

Severe vasodilation causes by bacterial toxins

1) NE ( levophed) : mostly alpha 1 ( problem is also constricts renal arteries ( reduces renal blood flow elevated BUN)
2) DA

Question 11

Dopamine

Answer 11

Vasoconstriction all peripheral arteries except renal Aries ( renal vasodilatory effect . Increased blood flow to kidneys )

Also hits b1 +I +C
alpha 1 : peripheral vasoconstriction of all peripheral arteries except renal

Question 12

Isoproterenol

Answer 12

Mostly beta receptors like epinephrine

Question 13

Phenylephrine

Answer 13

Alpha 1 nasal decongestant

Question 14

Clonidine

Answer 14

Alpha 2 : neg fb on NE
Anti adrenergic : decrease BP , bradycardia , drowsiness,

But has adrenerigc effects like dry mouth and constipation

Question 15

ALbuterol, metaproterenol, terbutaline, ritodrine

Answer 15

Pure beta 2 agonists

Question 16

Prazosin

Answer 16

Minipress

Alpha 1 blocker

Question 17

Prazosin

Answer 17

Minipress

Alpha 1 blocker

Question 18

Should not be used 1st line for HTN alone without BPH

Answer 18

T

Question 19

Alpha blockers Should not be used 1st line for HTN alone without BPH

Answer 19

T

Question 20

Terazosin

Answer 20

Hytrin
Alpha 1 blocker

Question 21

Tamsulosin

Answer 21

Flomax ( alpha 1 blocker )

Question 22

Tamsulosin

Answer 22

Flomax ( alpha 1 blocker )

Question 23

Doxazosin

Answer 23

Cardura
Alpha 1 blocker

Question 24

Phentolamine

Answer 24

Regitine ( IV /IM )

Alpha blocker used for HTN crisis associated with

1) pheochromocytoma ( epi secreting tumor of adrenal gland)
2) cocaine overdose HTN crisis
3) MAOI / tyramine interaction HTN crisis

Do NOT used BB alone with above crisis

Question 25

BB MOA

Answer 25

Vasodilate systemic arteries but vasoconstrict peripheral vasculature ( skin fingers )

Question 26

Anticholinergic : atropine

Answer 26

Flushing - red as a beet
Anhidrosis - dry as a bone
Hyperthermia - hot as a hare
Blurry vision: mydriasis blind as bat
Agitated : mad as a hatter
Urinary rentention: full as a flask
Tachycardia