ANS Flashcards
ANS
complex network of cells that controls body’s internal state
* regulates & supports many diff internal processes subconsciously
* only part of PNS
* collection of neurons that influence activities
Nervous System function
responsible for sensing info, integrating, & controlling response through signal transmission & transduction
anatomy of the major branches of NS
CNS: brain & spine
PNS: all neurons outside of brain & spine
PNS function
afferent & efferent fibers that relay signlas btwn the CNS & the periphery
CNS function
integrative & control centers
branches of PNS
afferent division: sensory
* conducts impulses from receptors to CNS
efferent division: motor
* conducts impulses from CNS to effectors
* effectors = muscles & glands
branches of efferent division
somatic NS (SNS): voluntary
* CNS to skeletal muscles through neuromuscular junctions
ANS: visceral (involuntary) motor nerve fibers
* conducts impulses from CNS to cardiac muscle, smooth muscle, & glands
branches of ANS
sympathetic: fight or flight
parasympathetic: rest & digest
* conserves energy
SNS
- sends signals through ANS nerves to adrenal glands
- adrenal glands respond by pumping epinephrine (adrenaline) into bloodstream
- both epinephrine & norepinephrine (NE) are neurotransmitters produced by SNS
pancreas
exocrine pancreas: secretion of digestive enzymes & ions & water into duodenum of GI tract
* makes up >95% of pancreatic tissue
endocrine pancreas: controls BG levels by secreting polypeptide hormones insulin & glucagon
stress pathway
hypothalamus ➞ secretes CRH ➞ activates pituitary gland ➞ secretes ACTH ➞ signals adrenal gland ➞ secretes gluticorcorticoids
stress response
inhibits parasympathetic neurons & activates sympathetic neurons
gluticocorticoids
- gluticocorticoid levels remain high with prolonged stress
- cortisol = main one in humans
- cortisol levels ↓ at night
- no sleep = cortisol levels remain high ➞ high BP
physiological reactions to gluticocorticoids
- ↑ BG from ↑ gluticocorticoids & ↓ glucose uptake into skeletal muscles
- ↑ likelihood of catecholamines ↑ lipolysis & ↑ BP
- inhibits protein synthesis & ↑ proteolysis
- is anti-inflammatory & immunosuppressive
which gland secretes gluticocorticoids
adrenal cortex of adrenal gland
catecholamines
any of a class of aromatic amines that includes a number of neurotransmitters
* ex: epinephrine & dopamine
endocrine signaling vs neurotransmitter signaling
endocrine signaling acts via hormones secreted into blood control processes that rely on duration rather than speed
neurotransmitter signaling acts via electrical signals to control rapid responses
ANS neurons
- having 2 diff neurons = more control
- both have cholinergic preganglionic neurons: release ACh
- both neurons have cholinergic (nicotinic) receptors
preganglionic vs postganglionic fibers
preganglionic: synapses with the cell body of the second neuron
postganglionic: axon of second neuron that innervates the effector organ
ganglion
cluster of neuron cell bodies outside the CNS
nerve
bundle of axons in the PNS
ACh: receptor type
cholinergic:
* nicotinic on all preganglionic fibers
* muscarinic on all parasympathetic target organs
ACh is secreted from:
- all preganglionic neurons
- all parasympathetic postganglionic neurons
NE receptor type
adrenergic
* cells of specific tissues
* mainly affects blood vessels
NE secreted from
postganglionic neurons of SNS
NE functions in ANS
- SNS: fight or flight response
- more focused
- ↑ alertness, arousal, & attention
- constricts blood vessels
- maintain BP during stress
- ↑ systolic BP (SBP)
epinephrine receptor type
adrenergic
* cells of various tissues/organs
* heart, lungs, muscles, vessels
epinephrine secreted from
postganglionic fibers of SNS
epinephrine functions in ANS
- SNS: fight or flight
- ↑ HR
- dilate muscles
- ↑ breathing
- ↑BG
- ↑strength & physical performance
sympathetic pathway
- short cholinergic preganglionic fibers ➞ release ACh
- cholinergic (nicotinic) receptors on postganglionic neurons
- long adrenergic postganglionic neurons
- effector organ has adrenergic receptors (⍺ or β)
cholinergic vs adrenergic fibers
cholinergic release ACh
adrenergic release NE or epinephrine
parasympathetic pathway
- long cholinergic preganglionic fibers
- nicotinic receptor on short cholinergic postganglionic neuron
- effector organ has cholinergic receptors (muscarinic)