ANS Flashcards
What is taype of Alpha and beta nonspicific agonists ?
And what is indication for Direct binding to and stimulation of both alpha and beta receptors?
ركز معي انت عندك اشي بشتغل على الفا و بيتا مش محدد و مفعل لدواء ..!
Adverse effects 》》 عكس ال indication (arrhythmic . Hypotension . Palpitation زيادة ضربات القلب . Dyspnea
- )Dopamine…….. Shock
- )Dobutamine …… Heart failure
- )Norepinephrine…..Shock and cardiac arrest
- ) Epinephrine ………Shock . hypotensive crisis severe bronchospasm , ophthalmic agent , to produce local vasoconstriction to prolong action of local anesthetics
- )Metaraminol……..Shock . prevention of hypotension
What is taype of Alpha and beta nonspicific agonists ?
And what is indication for Mixed action: binding to and activation of alpha and beta?
Ephedrine》》》》\\\\\
\((Broxchodailation .Hypotensive episodes))//
Pseudoephedrine/////
What is taype of Alpha and beta nonspicific agonists ?
And what is indication for indirect action?
Amphetamine… CNS .ADHD
Cocaine…drug of abuse
What is taype of Alpha spicific agonists ?
And what is indication for Direct binding to and stimulation of alpha receptors (Alpha1 agonists) ?
Phenylephrine…..Shock . allergies, otitis media.
What is taype of Alpha spicific agonists ?
And what is indication for Direct binding to and stimulation of alpha receptors (Alpha agonists) ?
Adverse effects 》》 blurred vision عدم وضوح الرؤية . Arrhythmias . ECG changes
Midodrine……hypotension
**) Clonidine……hypertensionالدوا الوحيد الي بعالج ال الهايبر
هدول ياخذو من الفم لكن الكلوندين ياخذ ايضا عن طريق لزقات
What is taype of Beta-spicific agonists ?
And what is indication for Binding to both beta1 and beta2 receptors?
حبيب هاي كل شغلها ع prevention of bronchospasm و كمان لل هايبوتن و البرادي كارديا
Adverse effects 》》anxiety, fatigue, Cardiovascular, tachycardia,palmonary
Isoproterenol》》Binding to both beta1 and beta2 receptors《《 ((indication))…shock, cardiac arrest, arrhythmias; heart block.. هاي بشتغل ع القلب , bronchospasm لتجنب الخنق النتاج عن ansethesia
☆
Albuterol
Metaproterenol
Salmeterol
Terbutaline….》 Binding to and activating beta2 receptors
((( لمعالجة - Asthma - COBD)))
تاخذ هذه الادوية ( parenteral , oral , nebulaizar )
ADRENERGIC ANTAGONISTS
What is taype of Nonselective adrenergic blocking agents ?
هاي بتعمل بلوك عَ
( alpha beta R antagonist )
Labetalol .. 》》 Indication ( hypertension, pheochromocytoma)
Carvedilol 》》 ( hypertension , heart failure)
Amiodarone 》》 ( arrhythmias ) مهمة هاي
What is taype of Nonselective alpha-adrenergic blocking agents ?
هي بس وحدة
Phentolamine 》》 Blocks both alpha1 and alpha2 receptors
اذا تسرب هاذا الدوا دغري بعطي نورابنيفرين او دوبامين
بعمل عندي hypertension
و الدوا هاد بعطيه بس بريتنترال
و من اعراضه tachycardia , hypotension
What is taype of Alpha1-selective adrenergic blocking agents ?
هاي تاعت ال zosin
Doxazosin Alfuzosin Prazosin Tamsulosin Terazosin
( Treatment 》 hypertension , prostatic hyperplasia )
اثاره كل اشي بتعرفوه
What is taype of Nonselective beta-adrenergic blocking agents ?
هاي olol
Propranolol
Nadolol
Pindolol
Treatment 》 hypertension
What is taype of Beta1-selective adrenergic blocking agents ?
هاي كمان فيها olol
Atenolol 》 MI , angina , hypertinsion .
Acebutolol 》 hypertinsion
Betaxolol 》 hypertinsion open-angle glaucima
Bisoprolol
Esmolol
Metoprolol
Cholinergic agonists
What is taype of Direct-acting cholinergic agonists ?
هاي بتحكي عن الارتباط على المسكارنك رسيتور بس زي البارا سيماستك
.
They bind to and activate the cholinergic receptors (usually muscarinic receptors)
Bethanechol 》 esophageal reflux , neurogenic
(( Pilocarpine 》 bladder)) 》 relive increased intraocular pressure
Cevimeline 》 symptoms of dry mouth
What is taype of Indirect-acting cholinergic agonists ?
They inhibit acetylcholinesterase the enzyme responsible for breaking down and terminating the action of acetylcholine, thus allowing acetylcholine to accumulate in the synaptic cleft and act more strongly
أنها تمنع أستيل كولينستريز الإنزيم المسؤول عن تكسير وإنهاء عمل أستيل كولين ، مما يسمح للأسيتيل كولين بالتراكم في الشق المشبكي والعمل بقوة أكبر
Edrophonium》
Neostigmine》》》Management of myasthenia gravis
Pyridostigmine》
Donepezil》 Management of Alzheimer dementia
Rivastigmine》cortex
What is taype of other agents ? And antidote ?
Nerve gas . It is Irreversibly لا رجوع فيه
Antido- Pralidoxime . It is Reactivates acetylcholinesterase
