ANS Flashcards
SNS
fight or flight
PNS
rest and digest
Enteric Nervous
gastrointestinal
ANS afferent source of descending pathway (mainstructure) and receiving Affarent info (structure)
Hypothalamus for both
Somatic nervous system major receiving afferent (structure) and major souce of decending info (structure)
thalamus recieve
decending cerebrum
ANS vs vs CNS and PNS
has 2 neurons
How does ANS get to structures
it exits the ventral horn and then synapses with ganglia and then goes to structure
synapse in ANS vs others
it has electrical synapsing
Preganglionic and postganglionic fibers are
pre are lightly myelinated post are not myelinated
sympathetic fibers are found
T1-L3 thoracolumbar ganglia is closer to spinal cord
parasympathetic are found
CN 3,7,9,10 S2-4 craniosacral ganglia is closer to target effector
SNS neurotransmitter
ACh pre NE post
PNS neurotransmitter
ACh pre and post
SNS Fx 4 es
Exercise Emergency Excitement Embarrassment
SNS Fx to eyes
pupil dilation eyelid retraction
SNS on glands
inhibition of salivation and lacrimation
stim of sweat gland
SNS on CVS
vasoconstriction increase HR and CO piloerection
SNS on hair
Piloerection
SNS on neural
reduction in neural output
SNS on digestive tract
reduction
SNS on hormones
hormones released Epi and NE Glucagon
SNS pregang originate from
lateral horns
3 routes of SNS
Travel to sympathetic trunk via white communicating rami and synapse immediately with postganglionic neurons at the same spinal cord level - BV and skin/LE Travel to sympathetic trunk via white communicating rami and either ascend or descend to synapse in more cranial or caudal ganglia - BV and skin/LE Continue through trunk without synapsing, and later synapse with postganglionic neurons in prevertebral ganglia - go to organs
SNS for postgang
they diverge and go to multiple target tissues
single pre gang will have multiple targets allows for SNS to activate targets in response to stress
SNS on Viscera
heart lungs gut kidneys liver bladder reproductive organs
SNS on lungs
bronchodilation
PNS Fx
conserve energy use and build energy stores
PNS on eyes
constriction
PNS on glands
activation salivary and lacrimal
PNS on HR
slowing HR vasodilation
PNS on lungs
broncoconstriction
brainstem pregang nuclei
EW nu sup and inf salivary nu nu ambiguous dorsal motor nu of vagus
sacral pregang nu
lateral horns
EW nu go to
ciliary muscles for pupil constriction
Sup and inf salivary nu go to
salivary and lacrimal glands
nu ambiguous go to
cardiac muscles slowing HR
sacral pregang nu go to
colon, rectum and for vasodilation lungs for bronchodilation gut for increased motility and digestion
Dual innervation of ANS
most structures on innervated by SNS and PNS
dual innervation exceptions in ANS
sweat glands erector pili most blood vessels adrenal medulla
How do the single innervated things regulate?
down regulation of SNS
SNS vs PNS responses
SNS is longer lasting bc
divergence of pregang
longer unmyelinated
slower inactivation
presence of NE and Epi
accelerated parasympathetic response can be activated during
paradoxical fear - no way to win or escape
ANS controlled by
- Hypothalamus
- Brainstem nuclei
- Amygdala and other limbic structures
- Medial prefrontal cortex
- Insular cortex
ANS regulated by
- Baroreceptors
- Chemoreceptors
- Osmoreceptors
- Thermoreceptors
ANS pathway

Affarent input serves for ANS
- Feedback input via solitary nucleus for local autonomic reflexes
- Inform higher integrative centers of more complex patterns of stimulation that may signal danger and/or may require more multi-system control
Afferent input visceral pain
Some of the 2⁰ neurons in the dorsal horn that receive visceral sensory input are part of the anterolateral system
REFERRED PAIN
•Travel to VPL of thalamus and then projects to insular cortex for integration
Modulation of ANS
Central autonomic network
insular cortex
medial prefrontal cortex
hypothalamus
hippocampal formation, amygdala
Central autonomic network modulation
•accounts for integration of visceral input with input from other sensory modalities and from higher cognitive centers
insular cortex modulation
primary visceral sensory area
medial frontal cortex modulation
primary visceral motor area
- Example activity:
- Blushing in response to embarrassing experiences
- Vasoconstriction and pallor in response to fear
- Autonomic responses to sexual situations
hypothalamus modulation Fx
•Controls blood flow, regulates energy metabolism, regulates reproductive activity, and coordinates responses to threatening conditions
hypothalamus modulation projections
reticular formation
PNS pregang nerves
brainstem nerves
PNS and SNS nuerons
Hippocampal formation, amygdala modulation
pulls from memories and emotions
Enteric system controls
- Exerts control of gastrointestinal system through neuronal system embedded in the lining of GI organs
- Peristalsis
- Segmentation – all over the place kind of like a washing a machine
- Hormone secretion
- Gastrin, secretin
Enteric system neurotransmitters
90 percent of seretonin used
50 percent of dopamin used
what modulates enteric system
SNS and PNS
but also opperates independently of SNS and PNS