ANP 3 FINAL REVIEW DECK Flashcards
What is Sinemet, what is it used for, and how does it work?
Dopaminergic agent
Sinemet is a combination of carbidopa & levodopa and is used to treat symptoms of Parkinson’s (muscle stiffness, tremors, spasms, and poor muscle control)
Parkinson’s may be caused by low levels of dopamine in the brain and Sinemet allows the body to make its own dopamine. The carbidopa makes sure the levodopa gets to the brain where it is needed.
(T or F) You should NOT use Sinemet in someone who has narrow-angle glaucoma.
True
(T or F) You should NOT use Sinemet in someone who has used a MAO inhibitor in the last 14 days.
True
(MAO inhibitor examples; isocarboxazid, linezolid, methylene blue injection, phenelzine, and ranylcypromine, azilect/rasagiline, eldepryl/selegine)
What does a person taking Sinemet want to avoid?
-avoid iron supplements
-avoid high protein diet
(makes it harder for the body to digest and absorb Sinemet)
What diseases can cause constipation?
-neurological disorders (Parkinson’s, spinal cord injuries, stroke, multiple sclerosis)
-metabolic and endocrine disorders (hypothyroidism, diabetes, chronic kidney disease, bowel cancer, diverticulitis)
What is the most common childhood leukemia?
Acute Lymphoblastic Leukemia
(Bone marrow makes too many lymphocytes)
80% of all pediatric leukemia cases
What are some signs and symptoms of ALL?
-bone pain
-symptoms r/t pancytopenia (SOB, dizzness, headache, rapid or irregular heartbeat)
-fever
-fatigue
-pallor
-bleeding
-bruising
-infections
-chills
-sore throat
-mouth sores
-severe cough
-diarrhea
-swollen lymph nodes
-cuts or sores that drain pus
-bruising easily
-heavy or prolonged bleeding
-blood in stools
-petechiae or purpura
What is the normal range for WBC on a CBC?
WBC 4500 - 11000 cells per microliter
What is the normal range for RBCs on a CBC?
4.5 million - 5.9 million cells per microliter for men
4.1 million - 5.1 million cells per microliter for women
What is the normal range for Hgb?
14 - 17 grams per deciliter for men
12.3 - 15.3 grams per deciliter for women
What is the normal range for Hct?
41.5% - 50.4% for men
35.9% - 44.6% for women
What is a normal range for MCV?
80 - 96
What is a normal range for platelets?
150000 - 450000 platelets per microliter
What is SCV syndrome?
T-CELL ALL OR T-CELL LYMPHOMA CAN PRESENT WITH AN ANTERIOR
MEDIASTINAL MASS AND SYMPTOMS R/T COMPRESSION OF THE MASS ON THE
TRACHEA AND BLOCKAGE OF VENOUS RETURN AND LYMPHATIC DRAINAGE
How does SVC present?
- SVC PRESENTS WITH WHEEZING, DYSPNEA, DYSPHAGIA, CYANOSIS. PLEURAL
AND PERICARDIAL EFFUSIONS CAN OCCUR
(T or F) SVC is an oncologic EMERGENCY!
T
Is SVC syndrome common in the pediatric population?
SVC is rare in the pediatric population. The peak occurrence of SVC syndrome in children is during infancy and another smaller peak during adolescence. The overall morbidity and mortality rates are 30% and 18%, respectively.
What is the most common rheumatologic condition in children?
Juvenile Idiopathic Arthritis
What is the single most important disease that is mistaken for juvenile idiopathic arthritis?
Leukemia
What is POTS?
Postural Orthostatic Tachycardia Syndrome
(a) frequent complaints of dizziness, lightheadedness, palpitations, tremor
(shakiness), generalized weakness, blurred vision or loss of vision, exercise intolerance, and fatigue;
(b) increase in heart rate of greater than or equal to 30 beats per
minute in adults (>19 years) or 40 beats per minute in children (<18 years) when
moving from a recumbent position to standing, the changes occur within 10 min
of standing; and
(c) the absence of orthostatic hypotension (drop in systolic blood
pressure of more than 20 mmHg)
The accepted duration of symptoms requires a
minimum length of 6 months.
*What position best helps to relieve symptoms of POTS?
sitting