Anosognosia and related phenomena Flashcards

1
Q

Name three disorders of awareness from mild to severe

A
Mild
- denial
- impaired self-awareness (ISA)
- anosognosia
Severe
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2
Q

What is anosognosia?

A

Complete unawareness of a lost neurological and/or neuropsychological function

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3
Q

What is impaired self-awareness (ISA)?

A
  • partial syndrome of unawareness of the disturbed function
  • patients with ISA show some awareness of their impairments
  • may use both defensive and non-defensive approaches for coping with their limited awareness of an impaired function
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4
Q

What is denial? (4)

A
  • a psychological method of coping with a loss or threat of loss that has personal significance to the individual
  • transforms reality to suit the purposes and wishes of the individual
  • ranges from a normal approach of coping to an unadaptive psychological defense
  • presence of denial complicates patient management
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5
Q

What is the difference between:
ISA (without denial of disabilty)
and
Denial of disability (in absence or presence of ISA)

A

Patients with ISA (without DD):

  • often perplexed when given feedback about their impairments
  • no negative or positive reaction

Persons with DD (in absence or presence of ISA):

  • often become irritated, if not agitated, when given feedback
  • often disregard feedback
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6
Q

In what way can be shown that patients with anosognosia have implicit knowledge of their impairments?

A
  • some patients with hemiplegia give worse estimates of bimanual abilities when questioned in first-person form than when questioned in third-person form
  • patients deny paralysis but accept to stay in bed or wheelchair
  • patients with anosognosia with hemiplegia may find excuses not to perform a bimanual tak even though they do not admit it is because of their paralyzed arms
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7
Q

What is neglect?

A
  • failure to report, respond or attend to stimuli on the opposite side of space to the lesion
  • impairment not caused by simple sensory or motor deficits
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8
Q

What is somatoparaphrenia?

A
  • delusional belief whereby a patient feels that a part of one’s body (e.g. paralyzed limb) does not belong to his/her body
  • typically associated with neglect
  • often in anosognosia for hemiplegia
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9
Q

What is misoplegia?

A

Morbid dislike or hatred of paralysed limbs in patients with hemiplegia

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10
Q

What is anosodiaphoria?

A

Condition in which brain injured patients seem indifferent to the existence of their handicap

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11
Q

What is confabulation?

A
  • memory disturbance characterized by verbal statements or actions that inaccurately describe history, background, and present situations
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12
Q

How is confabulation distinct from lying?

A

In confabulation there is no intent to decieve and because individuals are unaware that their information is incorrect

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13
Q

What is alexithymia?

A

Alteration in emotional processing characterized by:

  • difficulty in identifying emotions and differentiating them from other physical states
  • difficulty in describing emotions
  • limited ability to fantasize scenarios with significant emotional context
  • concrete cognitive style that disregards the complex emotional, motivational, and symbolic aspects of human behaviour

-> dysfunction in emotional awareness

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14
Q

Give two reasons why disorders of self-awareness like anosognosia and ISA negatively influence the process and outcome of neurorehabilitation

A
  • affect patients’ desire/motivational to follow treatment instructions or hamper rehabilitation
  • cause considerable frustration to relatives who try to provide assistance
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15
Q

Which two neuropyschological deficits have been discussed to contribute to anosognosia?

A
  • episodic memory
  • executive functioning

(also: motivation plays a role as it is required to engage in self-monitoring nd emotional activation marking errors as significant are often overlooked aspects of performance monitoring that may underlie anosognosia in some patients)

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16
Q

Name 3 models of anosognosia

A
  • Conscious Awareness System (CAS) (Schachter, 1991)
  • Pyramid model (Crosson et al, 1989)
  • New cognitive model (Rosen, 2011)
17
Q

What is the Conscious Awareness System (CAS)?

A
  • located in the medial and lateral parietal regions
  • recieves input about the state of individual functional modules (e.g. perceptual or motor)
  • passes the information on to an executive (frontal system)

Anosognosia for specific deficits -> disconnection of the CAS from individual modules

More generalized anosognosia -> damage to the CAS or the executive system

18
Q

What 3 possible levels of impairment of awareness with different behavioural implications are distinguished in the Pyramidal model?

A

A) Intellectual awareness
(i.e. evident when patients amdmit to having a particular difficulty)
Deficit -> patient does not admit to have a particular deficit

B) Emergent awareness
(i.e. the deficit becomes evident to patients only in the course of action)
Deficit -> patient can admit verbally to having a deficit but may fail to recognize the deficit as it occurs

C) Anticipatory awareness
(i.e. patients are able to consider the functional implications of the deficit and therefore their own limitations)
Deficit -> patient can admit verbally to having a deficit, realizes the difficulty as it occurs, but fails to foresee reallistically the functional implications of the deficit

19
Q

What is the new cognitive model of anosognosia by Rosen?

A

A working model that identifies specific functions that may be important for awareness of changes in one’s ability

  • performance monitoring
  • emotional processing
  • memory
20
Q

How is the level of awareness usually determined?

A

On the basis of discrepancies between:

  • the patient’s assessment of his/her abilities
    and:
  • caregiver’s (relative’s) assessment of the patient’s abilities
  • clinician’s assessment of the patient’s abilities
  • ‘objective’ measures of impairment (e.g. neuropsychological test results)

-> The greater the discrepancy, the greater the degree of unawareness of lack of insight

21
Q

What is an example of a method for assessment by caregivers/relatives?

A

The Patient Competency Rating Scale

Assesses discrepancies between patients and caregivers in judgement relating to:

  • activities of daily living
  • cognition
  • interpersonal relationships
  • emotion

Ratings on Likert scale

22
Q

What are concerns regarding validity of the Patient Competency Rating Scale?

A
  • unclear to what extent a caregiver can be expected to provide an accurate evaluation of a patient’s functioning in different areas
  • caregivers’ ratings may be influenced by:
    - degree of burden experienced by the caregiver
    - depression and anxiety in the caregivers
  • accuracy of evaluations influenced by the type of caregiver (spouses>first degree relative>second degree relative)
23
Q

What is an example of a method for assessment by clinical judgement?

A

The Self-Awareness of Deficit Interview

Semi-structures interview for clinicians investigating three major domains

  • self-awareness of deficit
  • self-awareness of functional implications of deficit
  • ability to set realistic goals

Assessment of patients’ understanding of nature and severity of brain injury, the present condition, the awareness of deficit and cognitive ability to evaluate its consequences

24
Q

What method can be used to reduce the problem that neuropsychological tests are not ideal metric to relate them to patients’ awareness of their abilities in real life?

A

Use of prediction and/or postdiction methods

Prediction: how well do you think you will do?
Postdiction: how well do you think you did it?

25
Q

Why is the new approach by Rosen to assess self-awareness (after standardized task that measures real world functional abilities, ask patient how he/she performed in terms of percentiles) an inprovement over other approaches?

A
  • does not rely on an informant

- uses tasks that tap into real funtional impacts of neurological disease

26
Q

According to the article of Fotopoulou (2008), confabulations serve as important functions of.. (2)

A
  • Self-coherence

- Self-enhancement

27
Q

What are 4 ways to assess anosognosia?

A
  • Assessment by caregivers/relatives (Patient Competency Rating Scale)
  • Clinical judgement (Self-Awareness of Deficit Interview)
  • Comparison to performance in neuropsychological testing (prediction/postdiction)
  • New approach by Rosen (2011)