ANESTHESIA Flashcards

1
Q

TYPES OF ANESTHESIA

A

o general
o sedation
o regional

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2
Q

GENERAL VS SEDATIVE VS REGIONAL

A

o GENERAL = suppression of activity in the CNS; unconscious & total lack of sensation

o SEDATION = Inhibition of transmission of nerve impulses between higher & lower centers of the brain; inhibition of anxiety & memory

o REGIONAL = use of local anesthetics to make a portion of the body insensate by blocking transmission of nerve impulses between a part of the body and the spinal cord
⦁ Peripheral = inhibits sensory perception within a specific location (nerve blocks)
⦁ Central = local anesthetic delivered around the spinal cord - removes sensation of the body below the level of the block (spinal & epidural)

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3
Q

ENDPOINTS OF ANESTHESIA

A

⦁ Hypnosis = temporary loss of consciousness & loss of memory
⦁ Analgesia = lack of sensation; autonomic reflexes are blocked
⦁ Muscle Relaxation

Amnesia (memory loss) = Benzodiazepines
Immobility = Muscle relaxants & Paralytics
Analgesia = Opiates, local anesthetics, Ketamine, NSAIDS
Hypnosis = Barbiturates, Propofol, Etomidate
Anesthesia (inhaled agents) = all of the above!

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4
Q

post op cognitive dysfunction more common with

A

cardiac surgery & elderly patients

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5
Q

anesthesia risks

A
⦁	death
⦁	MI
⦁	PE
⦁	Post op N/V
⦁	Post op cognitive dysfunction (persistent confusion lasting weeks or months; more common with cardiac surgery & in the elderly)
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6
Q

the greatest predictor of the probability of a complication occurring

A

ASA classification

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7
Q

the higher the ASA class =

A

increased likelihood of surgical or anesthetic complications

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8
Q

the ROOT CAUSE of 11% of adverse anesthetic events =

A

INCORRECT PRE-OP ASSESSMENTS

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9
Q

ASA CLASSIFICATION

A

⦁ ASA I = normal healthy patient; no smoking, and none/minimal drinking

⦁ ASA II = pt with mild systemic dz; smoker, or more than minimal drinking, pregnancy, obesity, well controlled DM, well controlled HTN, mild lung dz

⦁ ASA III = pt with severe systemic dz, not incapacitating; DM, poorly controlled HTN, distant hx of MI / CVA / TIA / cardiac stent / COPD / ESRD. Dialysis, active hepatitis, implanted pacemaker, EF < 40%, congenital metabolic abnormalities

⦁ ASA IV = pt with severe systemic dz that is a constant threat to life = recent hx of MI / CVA / TIA / cardiac stent. Ongoing cardiac ischemia or severe valve dysfunction, implanted ICD, EF < 28%

⦁ ASA V = moribund pt who is not expected to survive without the operation; ruptured abdominal or thoracic aneurysm, intracranial bleed with mass effect, ischemic bowel in the face of significant cardiac pathology

⦁ ASA VI = pt is has already been declared brain dead, and whose organs are being removed for transplant

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10
Q

regional / local anesthesia

A

pain blocked from a part of the body using local anesthetics

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11
Q

types of regional anesthesia

A
⦁	Infiltrative
⦁	Peripheral nerve block
⦁	IV regional anesthesia
⦁	Central nerve block
⦁	Topical anesthesia
⦁	Tumescent anesthesia
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12
Q

INFILTRATIVE ANESTHESIA (type of regional)

A

local anesthetic injected in a small area to stop sensation

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13
Q

local anesthetic injected in a small area to stop sensation

A

infiltrative

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14
Q

PERIPHERAL NERVE BLOCK (Regional type)

A

local anesthetic injected near a nerve that provides sensation to a portion of the body

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15
Q

local anesthetic injected near a nerve that provides sensation to a portion of the body

A

peripheral nerve block (regional / local)

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16
Q

IV Regional Anesthesia (Bier Block) (type of regional)

A

dilute local anesthetic infused to a limb through a vein with a tourniquet placed to prevent the drug from diffusing out of the limb

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17
Q

dilute local anesthetic infused to a limb through a vein with a tourniquet placed to prevent the drug from diffusing out of the limb

A

IV regional anesthesia (bier block)

18
Q

dental block or digital nerve block =

A

peripheral nerve block

19
Q

Infusion or injection of local anesthetic in or around a portion of the CNS (ex: Spinal - intrathecal, and epidural)

A

central nerve block

20
Q

central nerve block

A

Infusion or injection of local anesthetic in or around a portion of the CNS (ex: Spinal - intrathecal, and epidural)

21
Q

topical anesthesia

A

special formulation that diffuses through the skin or mucous membranes (ex: EMLA patches)

22
Q

tumescent anesthesia

A

large amount of dilute local anesthesia is infiltrated into the subcutaneous tissue (used in liposuction / various other procedures)

23
Q

NEUROAXIAL ANESTHESIA INDICATIONS & CONTRAINDICATIONS

A

= spinal (intrathecal) or epidural

  • Indications
    ⦁ surgery or pain
    ⦁ appropriate distribution of anesthesia
  • Contraindications
    ⦁ Patient refusal
    ⦁ Infection (near site of injection)
    ⦁ Coagulopathy (on any blood thinner)
24
Q

BENEFITS OF SPINAL ANESTHESIA

A

⦁ decreases surgical time by 12%
⦁ 25% less blood loss
⦁ 50% less intraoperative transfusion requirements
⦁ may decrease the incidence of DVT or PE

decreased surgical time, decreased blood loss, decreased intraoperative infusions, decreased risk of DVT/PE

25
BENEFITS OF EPIDURAL ANESTHESIA & ANALGESIA
⦁ less blood loss ⦁ reduced platelet aggregation ⦁ reduced stress response to surgery ⦁ decreased incidence of DVT ⦁ improved graft patency after LE revascularization ⦁ Patients with combined (general & epidural) for aortic surgery had lower incidence of death & lower incidence of major perioperative complications
26
COMPLICATIONS OF NEUROAXIAL ANESTHESIA
⦁ ****MOST COMMON = post procedural headache | ⦁ spinal hematoma or abscess
27
most common complication of neuroaxial anesthesia
post-procedural headache
28
SPINAL VS EPIDURAL
Spinal: injection = lumbar region only (below L2) Epidural: injection = anywhere along the spine Spinal: no specific levels Epidural: levels of chest, abdomen, pelvis, legs Spinal injection: many times just a one time dose Epidural injection: often a catheter is left in place for multiply injections
29
nerve localization for regional block (finding the nerve)
o Paresthesia o Nerve stimulation o Ultrasound
30
common plexus blocks
⦁ Interscalene ⦁ Supraclavicular ⦁ Axillary
31
local anesthetics = esters or amides
Esters = rapid hydrolysis in blood by pseudocholinesterase amides = metabolized in the liver
32
examples of Esters: and duration of action
- Short Acting: 45-60 min ⦁ Procaine (Novacaine) ⦁ 2-Chloroprocaine - Long Acting (180 - 360 min) ⦁ Tetracaine
33
examples of Amides: and duration of action
- Intermediate acting (75 - 90 min) ⦁ Lidocaine (Xylocaine) ⦁ Mepivicaine - Long acting (180 - 360 min) ⦁ Bupivacaine (Sensorcaine, Marcaine) ⦁ Ropivacaine (Naropin)
34
DRUG CONCENTRATION
- drug concentration = expressed as % - to convert % to mg/mL = multiply % x 10 - ex: 0.25% x 10 = 2.5 mg / mL - Epinephrine expressed as grams/mL (1:200,000) = 1 gram in 200,000 mL = 5 ug / mL (ug = have to move decimal 6 places over)
35
how to calculate dose
volume x concentration ex: 30 mL x 0.25% = 30 mL x 2.5 mg / mL = 75 mg
36
DIFFERENTIAL BLOCK
- Low concentration = sympathetic block - Intermediate concentration = sensory block - high concentration = motor block
37
low concentration = ________ block intermediate concentration = ________ block high concentration = _______ block
sympathetic sensory motor
38
BENEFITS OF ADDING EPINEPHRINE TO LOCAL ANESTHETICS
1) prolongs surgical anesthesia time 2) decreases peak serum levels; because maximum safe doses are higher when epinephrine is used 3) intravascular marker 4) decreases surgical site bleeding
39
WHEN TO NOT ADD EPI TO LOCAL ANESTHETICS
``` - when the vasoconstrictive properties of epi may compromise tissue perfusion ("end" arteries) ⦁ fingers / toes ⦁ penis ⦁ ear / nose ⦁ skin flaps ```
40
max dose of lidocaine with & without epi
4.5 mg/kg = without epi 7 mg/kg = with epi
41
treatment for local anesthesia toxicity
LIPOSIN (intralipid)