Anesthesia

Question 1

In “effects of buprenorphine added to bupivacaine infraorbital nerve blocks on isoflurane minimum alveolar concentration using a model for acute dental/oral surgical pain in dogs” JVD 2016 by Snyder, Snyder, and Hetzel,

What % reduction in MAC was seen in the bupivacaine block group? The bupivacaine and buprenorphine group?

Answer 1

Bupivacaine group: 22%
Bupivacaine and buprenorphine group: 19%

Question 2

In “effects of buprenorphine added to bupivacaine infraorbital nerve blocks on isoflurane minimum alveolar concentration using a model for acute dental/oral surgical pain in dogs” JVD 2016 by Snyder, Snyder, and Hetzel,

Was there a significant improvement in nerve block duration in the study?

Answer 2

No

Question 3

In “effects of buprenorphine added to bupivacaine infraorbital nerve blocks on isoflurane minimum alveolar concentration using a model for acute dental/oral surgical pain in dogs” JVD 2016 by Snyder, Snyder, and Hetzel,

At 3 days post nerve block, what % of dogs in the bupivacaine group still exhibited reduced MAC at testing? BupBup group?

Answer 3

Bupivacaine: 25%
BupBup: 50%

BupBup group - 4/8 reduced day 3, 3/8 day 4, and 2/8 day 5

Question 4

In “ effect of mepivacaine in an infraorbital nerve block on MAC of isoflurane in clinically normal anesthetized dogs undergoing a modified form of dental dolorimetry” by Snyder and Snyder in JAVMA 2013,

What percentage reduction in MAC was seen? What is considered clinically relevant?

Answer 4

23%
Anything over 20% - morphine reduces MAC by 48%