anemias

Question 1

some causes of sideroblastic anemia

Answer 1

TB drugs (isoniazid, pyrazinamide and cycloserine), chronic alcoholism, ALA synthetase deficiency, lead poison, myelodysplastic syndrome, copper def, zinc toxicity.

Question 2

microangiopathic hemolytic anemia would show what on peripheral smear?

Answer 2

schistocytes (as in HUS)

Question 3

pt comes in with hematuria, jaundice, and has been working out super hard or marching

Answer 3

traumatic hemolytic anemia due to prolonged repeated compressed tiny blood vessels. may also cause rhabdomyolysis which can be differentiated from hemolytic anemia thru ck enzyme levels.

Question 4

itp is

Answer 4

isolated thrombocytopenia. thought to be caused by platelet distruction or inhibition of platelet production by way of antibodies.

Question 5

ptt means

Answer 5

partial thromboplastin time. tells you how long it takes for blood to clot.

Question 6

medications that cause agranulocytosis (low leukocyte/wbc’s)

Answer 6

PTU, methimazole

Question 7

Fanconi’s anemia

Answer 7

congenital. leads to pancytopenia, and macroctyic anemia.

Question 8

first line therapy for fanconi

Answer 8

androgens and hematopoetic growth factors.