Anemia Flashcards
What is a normal hgb and hct for women?
Hgb <12 or Hct <36
What is a normal hgb and hct for men?
Hgb <13.5 or Hct <41
What is MCV?
What is MCH?
The avg hgb content in a RBC (ie a low MCH indicates low hgb content per cell, and on a peripheral blood smear would show up as hypochromia)
What is RDW?
Measure of variation in RBC size
What does a low RDW indicate?
means RBC are all around the same size
What does high RDW indicate?
means theres a lot of variation in the RBC size?
What are the two main types of microcytic anemia and what is the corresponding MCV?
- Iron Def Anemia
- Thalassemia
- also sideroblastic from lead toxicity, copper deficiency and zinc poisioning
**MCV <80
What is the mc cause of anemia worldwide?
Iron deficiency anemia
What should be high on your ddx for IDA?
- GI bleeding… you HAVE to rule this out
- PUD
- Cancer
- Nsaid use
- –also consider menstrual loses
What are some signs of IDA?
What are signs of severe IDA and at what Hct is it severe?
- Hct <25%
- chelosis
- smooth tongue
- brittle nails
- formation of esophageal webs (plummer vinson syndrome)
What will IDA lab work show?
a. dec ferritin
b. dec serum Fe
c. inc TIBC
This type of anemia is made of 4 protein chains (2 alpha and 2 beta)
Thalassemia
On peripheral smear, what disease shows target cells, basophilic stippling, polikocytes
Thalassemia
