Anemia Flashcards

1
Q

Define reticulocyte count

A

Ability of bone marrow to produce mature red blood cells

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2
Q

What is the difference between the increased and decreased reticulocyte count?

A

-Increased Retic Count (> 2%)
Bone marrow is adequately responding to anemia
Blood loss, hemolysis, response to therapy
-Decreased Retic Count (< 2%)
Inability of bone marrow to compensate for anemia
Normocytic, Microcytic, Macrocytic anemias

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3
Q

Define Mean Corpuscular Volume (MCV)

A

Volume or size of ave RBC

Classifies anemia

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4
Q

Define red blood cell count

A

of RBCs

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5
Q

Define hemoglobin

A

concentration of hemoglobin in whole blood

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6
Q

Define hematocrit

A

% of whole blood comprised of RBCs

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7
Q

Define mean corpuscular hemoglobin (MCH)

A

Weight of hemoglobin in ave RBC

Diagnosis of severe anemia

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8
Q

Define mean corpuscular hemoglobin concentration (MCHC)

A

Amount of hemoglobin present in ave RBC when compared to it’s size
Monitors therapy for anemia

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9
Q

Define red cell distribution width (RDW)

A

Measure of variability in RBC size

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10
Q

What diseases/conditions are associated with increased RBC count?

A
Polycythemia vera
Renal disease
Pulmonary disease
CV disease
High altitude
Erythrocytosis
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11
Q

What diseases/conditions are associated with decreased RBC count?

A
Anemia
Hodgkin’s disease
Multiple myeloma
Hemorrhage
SLE
Rheumatoid arthritis
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12
Q

What conditions are associated with increased HCT?

A

Erythrocytosis
Polycythemia vera
Shock

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13
Q

What conditions are associated with decreased HCT and Hb?

A

Cancer
Chronic disease
Blood loss
Hemolytic anemia

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14
Q

What conditions are associated with increased hemoglobin?

A

Polycythemia vera
CHF
COPD

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15
Q

What condition is associated with an increase or decrease in iron?

A

necessary for production of Hb

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16
Q

What condition is associated with an increase or decrease in ferritin?

A

Reflects body iron stores

17
Q

What condition is associated with an increase or decrease in ferritin?

A

Transport protein synthesized by liver

Regulates iron absortion

18
Q

What condition is associated with an increase or decrease in total iron binding capacity (TIBC)?

A

Iron binding capacity of RBC

19
Q

What condition is associated with an increase or decrease in Vitamin B12?

A

Necessary for production of RBCs

20
Q

What condition is associated with an increase or decrease in Folate-Vitamin B9?

A

neural tube development

21
Q

What test, examines for pernicious anemia?

A

B12

22
Q

What is the most common type of Anemia?

A

Iron deficient anemia

23
Q

What is the most common cause of macrocytic anemia?

A

Vitamin B12 deficiency

24
Q

What are the most common causes of Normocytic anemia?

A

Hemolytic, Aplastic

also decreased erythropoietin