Anemia Flashcards
How is anemia defined in males?
Hemoglobin <13.6 or hematocrit <40%
How is anemia defined in females?
Hemoglobin <11.9 or hematocrit <35%
Which MCV describes microcytic?
<80
Which MCV described macrocytic?
> 100
What does a low retic count mean in anemia?
Impaired RBC production (inflammation, renal disease, B12 deficiency)
What does a high retic count mean in anemia?
Acute blood loss or hemolysis
What causes macrocytic anemia?
B12 or folate deficiency (blood cells do not mature and condense)
What does a high MMA indicate?
B12 deficiency
What does a high homocysteine indicate?
B12 or folate deficiency
What does B12 deficiency present like?
- Cognitive impairment
- Peripheral neuropathy
- Gait abnormalities
What causes microcytic anemia?
- Iron deficiency*
- Sickle cell
- Thalassemia
What additional labs should we look at when working up microcytic anemia?
- Ferritin*
- Transferrin saturation (TSAT) <16%
How do we treat iron deficiency anemia?
100-200 mg oral elemental iron without food
What can enhance absorption of oral iron?
Vitamin C
When do we use parenteral iron?
- CKD
- Hemodialysis
- Unable to tolerate oral or failed
- Patient refused blood transfusions