Anemia

Question 1

ferritin

Answer 1

protein that stores iron in cells

Question 2

TSAT

Answer 2

Measures how much iron is bound to transferrin

Question 3

transferrin

Answer 3

protein that iron binds to in bloodstream

Question 4

TIBC

Answer 4

measures the blood’s capacity to bind iron with transferrin. works opposite to body’s current state

Question 5

microcytic anaemia

Answer 5

IDA
thalessemia

Question 6

macrocytic anaemia

Answer 6

vb12/folate deficiency

Question 7

drug-induced aplastic anemia definition

Answer 7

at least 2 of the following
WBC < 3.5x109/L
Platelet < 55x109/L
Hemoglobin < 10g/dL + RC < 30 x 109/L

Question 8

drugs inducing aplastic anemia

Answer 8

chloramphenicol, carbamazepine, phenytoin

Question 9

neutropenia

Answer 9

absolute neutrophil count <1500/µL

Question 10

clozapine associated with

Answer 10

neutropenia

Question 11

ptu/carbimazole associated with

Answer 11

neutropenia

Question 12

beta lactam abx associated with

Answer 12

neutropenia

Question 13

drugs causing hemolytic anemia in g6pd

Answer 13

fql, primaquine, sulfonylureas, henna, naphthalene

Question 14

drugs causing hemolytic anemia via immune induced

Answer 14

methyldopa, quinidine, penicillins, cephalosporins

Question 15

thrombocytopenia definition

Answer 15

platelet <100x10^9 /L or greater than 50% reduction from baseline

Question 16

what to use when HIT

Answer 16

doac

Question 17

drugs associated with thrombocytopenia

Answer 17

sulfonamide, carbamazepine/phenytoin, 2b/3ai