Andrenergic

Question 1

Where does adrenaline originate from?

Answer 1

Tyrosine — dopa — dopamine — noradrenaline — adrenaline

Question 2

What makes/activates monoamines?

Answer 2

MAO monoamide oxidase

Question 3

what’s the name of the transporter hat up takes noradrenaline?

Answer 3

VMat

Question 4

What drug blocks VMat and what is the result?

Answer 4

Reserpine, nerve is depleted of NA

Question 5

What are the 2 types of mao?

Answer 5

Mao a: sns, liver, gi, placenta

Mao b: cns, platelets

Question 6

List 3 Mao inhibitors?

Answer 6

Phenylzine- Mao a and b
Moclobernide- Mao a
Selegiline- mao b —- used for Parkinson’s disease

Question 7

What affect does crack cocaine have on na?

Answer 7

Stops uptake of na by blocking uptake channel… more na is used for signalling so prolongs euphoric feeling

Question 8

What is colonidine?

Answer 8

A2 receptor agonist, activates the receptors to stop na release

Question 9

What’s the purpose of COMT?

Answer 9

Uptake 2 channel for na, can also metaloblise na

Question 10

What is salbutamol?

Answer 10

B2 agonist, Asthma and premature labour

Question 11

What is atenolol?

Answer 11

B1 antagonist, used for hypertension and agnia

Question 12

What is prazosin?

Answer 12

A1 antagonist, used for hypertension

Question 13

what is labetalol?

Answer 13

A1 and b antagonist, used for hypertension

Question 14

What is clonidine?

Answer 14

Drug that affects A2 receptors

Question 15

What’s the effect of a blockers?

Answer 15

Causes vasodilation

Question 16

What’s the effect of b blockers?

Answer 16

Decrease force of contraction, decrease blood pa and vascular tone