ANCA Flashcards

1
Q

ANCA =

A

= Anti Neutrofiele Cytoplasmatische Antistoffen

= ontstekingsreacties in de vaatwand door anti neutrofiele antistoffen

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2
Q

Pathologie ANCA

A

ANCA activeert neutrofiele granulocyt -> plakken aan de vaatwand -> destructie vaatwand -> vasculitis

(C5a speelt hierin een rol)

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3
Q

Soorten ANCA (2)

A

c-ANCA = ANCA gericht tegen PR-3
(komt meer voor)

p-ANCA = ANCA gericht tegen MPO

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4
Q

Behandeling ANCA

A
  • Prednison
  • Plasmaferese
  • Rituximab
  • C5a remmer
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