Anatomy of Salivation and Swallowing Flashcards

1
Q

Describe the functions of saliva

A
  • Lubricate food
  • Lubricate mouth - speak (tongue, cheeks)
  • Oral hygiene
  • Lysozyme - enzyme that destroys microorganisms
  • Amylase
  • Transmitting diseases - eg. Rabies virus
  • Solvent that carries taste molecules to taste buds
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2
Q

List the components of saliva

A
  • Mostly water
  • Hypotonic
  • Rich in potassium and bicarbonate
  • Mucus
  • Enzymes including amylase and lingual lipase
  • Immune proteins - IgA, lysozyme, lactoferrin
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3
Q

State the 3 salivary glands

A

Parotid, submandibular, sublingual

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4
Q

State where the parotid gland is located and its duct

A
  • Largest of salivary glands
  • Sits lateral to mouth
  • Parotid duct passes over masseter and penetrates through buccinator into oral cavity
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5
Q

State where the submandibular gland is and its duct

A
  • Has a deep and superficial segment
  • Gland is a pacman shape around mylohyoid (muscle that forms floor of mouth)
  • Can be felt from below chin
  • Submandibular duct opens on floor of mouth medially
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6
Q

State where the sublingual gland is and its ducts

A
  • Located above mylohyoid

- Sublingual gland has many ducts that open more laterally into the oral cavity

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7
Q

Describe the control of salivary secretion

A
  • Control autonomic
  • Parasympathetic is main driver (increases saliva production)
  • Sympathetic also stimulates secretion of small amounts of saliva, but also causes vasoconstriction of arterioles
  • Sublingual and submandibular glands are supplied by parasympathetic from facial nerve
  • Parotid gland innervated by glossopharyngeal nerve (IX)
  • Any drug that inhibits mACh receptors inhibit salivary glands - inhibits parasympathetic system
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8
Q

Explain how an isotonic solution is secreted from salivary glands

A
  • Isotonic solution excreted from the acinus of the salivary glands
  • Myoepithelial cells move the salivary solution down the ducts
  • Ductal cells extract NaCl from the solution, creating an hypotonic solution
    • If the flow rate through the ducts is greater, then the solution becomes less hypotonic
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9
Q

Describe the structure of the oesophagus

A
  • Oesophagus posterior to larynx and trachea
  • Lies right of aorta and pierces diaphragm at T10
  • Oesophagus has many narrowing points
    • Junction of oesophagus with pharynx
    • Where oesophagus is crossed by arch of aorta
    • Where oesophagus is compressed by left main bronchus
      • At the oesophageal hiatus (at diaphragm)
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10
Q

State the distribution of muscle types along the oesophagus

A

Skeletal muscle at cranial end and smooth muscle at caudal end

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11
Q

State the 3 phases of swallowing

A
  • Oral prepatory phase
  • Pharyngeal phase
  • Oesophageal phase
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12
Q

Describe the oral prepatory phase

A
  • Voluntary
  • Tongue pushes bolus towards pharynx
  • Once bolus touches pharyngeal wall, pharyngeal phase begins
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13
Q

Describe the pharyngeal phase

A
  • Involuntary
  • Soft palate seals off nasopharynx
  • Pharyngeal constrictors push bolus downwards
  • Larynx elevates, closing epiglottis
  • Vocal cords adduct and breathing temporarily ceases
  • Opening of the upper oesophageal sphincter
  • Airway at risk of aspiration in pharyngeal phase
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14
Q

Describe the oesophageal phase

A
  • Involuntary
  • Closure of the upper oesophageal sphincter
  • Peristaltic wave carries bolus downwards into oesophagus
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15
Q

Describe how swallowing in a baby differs from adults

A
  • Epiglottis in baby projects upwards into nasopharynx
    • Able to breathe and feed at same time
    • Can’t speak
    • As baby grows, neck elongates to pull epiglottis down
  • Milk diverted laterally around epiglottis to oesophagus
  • Piriform fossa guides bolus down to oesophagus
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16
Q

Outline the neural control of swallowing

A
  • Mechanoreceptors on wall of pharynx detect bolus
  • Transmit through glossopharyngeal nerve into medulla (circuit of swallowing)
  • Then through vagus nerve to pharyngeal constrictors
  • Pharyngeal constrictor muscle pushes bolus down
17
Q

How do oesophageal tumours feel

A

Liquids can pass but solid bolus gives the feeling of food sticking

18
Q

Describe the pathology of mumps

A
  • Swelling over left parotid gland - inflammation
  • Also causes testicular/ovarian inflammation
  • Parotid glands have fibrous capsule that does not stretch
    - Painful as parotid glands pushing on fibrous tissue
19
Q

Describe the anatomical mechanisms that prevent gastro-oesophageal reflux and outline some of the clinical consequences of free gastro-oesophageal reflux

A
  • Functional sphincter formed from smooth muscle of distal oesophagus
  • Thickening of smooth muscle
  • Diaphragm pinches oesophagus to prevent reflux
  • Intra-abdominal oesophagus which gets compressed when intra-abdominal pressure rises
  • Mucosal ‘rosette’ at cardia
  • Acute angle of entry oesophagus
    • Rise in stomach pressure closes LOS
  • Barrett’s oesophagus can develop in reflux