Anatomy module 4.1 Flashcards
Systole
phase of contraction–Depolarize
Diastole
phase of relaxation–repolarize
Atrial and ventricular Diastole (late diastole)
Both atria and ventricles are relaxed
Blood is flowing from the veins into Right Atrium and into the Left Atrium
The AV valves are open and the SL Valves are closed
Atrial Systole
Initiated by depolarization
Preceded by the “P” wave of EKG
Atria contract
Blood flows from AV Valves to the Ventricles
Most Ventricular filling occurs before atrial systole
What is the advantage of atrial systole?
Forces last amount of blood out of the atrium into the ventricle.
Ventricular Systole (and atrial diastole)
Action potential has now traveled along the
Bundle of HIS to the ventricles.
It is preceded by the QRS wave of the EKG
The ventricles contract
The _____ventricular pressure causes the ______to ____ and a moment later the SL valve to _____. The ____ of ____valves cause the _____heart sound
(still a part of Ventricular Systole ( and atrial systole)
Increased AV Valves Close Open Closing AV valves first
The stage called _______occurse when the ______close but before the _____valves open.
Isovolumetric contraction
AV valves
SL Valves
Muscle contraction stays same length
Isovolumetric contraction
The stage called ______begings when _____valves _____.
Ventricular ejection
SL
Open
Ventricular diastole
Ventricles relax
Preceded by the T wave of EKG
Ventricular Diastole cont’d.
The _____ventricular pressure causes the SL valves to ____and a moment later the AV valves to____.
decreased
close
open
The closure of the ____ valves causes the ____ heart sound
SL
Second
The stage called ______occurs when the ____valves close but before the _____valves open
isovolumetric relaxation
SL
AV
Ventricular filling actually begins when the ____valves open
AV
Another cycle begins when the____fires another electrical signal
SA NODE
The volume of blood ejected from each ventricle per minute
Cardiac output
The number of contractions per minute
heart rate
Volume of blood ejected by a ventricle per beat
Stroke Volume
equation for CO, HR and SV
CO=SV*HR
Frank Sterling Law
The more the heart muscle is stretched during diastole, the greater the force of contraction during systole
Volume of blood returning to the right ventricle.
Venous Return
Degree of stretch on the heart before it contracts
Pre-Load
increases stroke volume
Forcefulness of contraction of individual ventricular muscle fibers
Contractility
increases stroke volume
Pressure that must exceed before ejection of blood from the ventricles can occur. “downstream”
After-Load
Decreases stroke volume
Substances that either increase or decrease contractility
Inotropic effect
Measurement of the % of blood leaving your heart each time in contracts
Ejection Fraction
EF=SV/EDV * 100
Cardiac Control centers are located….
Medulla oblongata
Originate in the cardioinhibitory center post-ganglionic axons release the neurotransmitter acetylcholine decrease rate of firing of SA node Responsible for vagal tone vagus nerve cause decrease in cardiac output
Parasympathetic signals
Originate in the cardioacceleratory center
post-ganglionic axons release the neurotransmitter norepinephrine
increase rate of firing SA Node
Increase contractility of cardiac muscle fibers
positive inotropic effect
Sympathetic signals
3 layers of blood vessel walls
Tunica Intima (Interna) SIMPLE SQUAMOUS Tunica Media VASCULAR Tunica externa (adventitia) FIBROUS CONNECTIVE
Only layer of capillary walls Innermost layer in direct contact with lumen consists of simple squamous epithelium smooth layer; facilitates flow of blood also known as endothelium
Tunica Interna
Contains smooth muscle
contains elastic connective tissue
middle layer
Tunica Media
Consists of fibrous connective tissue
outermost layer
Tunica externa (adventitia)
Sequence of flow of 3 major types of blood vessels
1) ARTERIES—2) CAPILLARIES—3) VEINS—Back to the heart
Carries blood away from heart
Arteries
Allows exchange of substances between blood and body tissues
Capillaries
Carries blood back to the heart
Veins
Wall contains intercellular CLEFTS
Wall consists of only simple squamous epithelial cells
Site of exchange between plasma and interstitial fluid
Capillaries