Anatomy Exam Two Flashcards
During filling the pressure in the atria is ___________ than the ventricles
higher
The overarching order of events in the cardiac cycle is:
__4__ Blood flow
__2__ Cardiac Muscle Contraction
__1__ Electrical conducting system and Cardiac Muscle Excitation
__3__ Pressure changes
Match EKG events to electrical events in the heart Atrial depolarization (excitation)
P-wave
Ventricular depolarization
QRS complex
Atrial repolarization
QRS complex
Ventricular repolarization
T wave
period of lack of electrical activity
isoelectric line
Pressure in the ventricles is ___________ than the atria during ventricular relaxation
lower
True or False: The papillary muscle contract together with the rest of the ventricular muscle
True
Activated to increase activity of the digestive system
parasympathetic nervous system
Craniosacral in origin
parasympathetic
Short preganglionic nerves
sympathetic
This structure provides concious input to the autonomic nervous system.
Cerebral cortex
Targets adrenergic receptors
sympathetic
Has pre-ganglionic and post-ganglionic neurons
both sympathetic and parasympathetic nervous system
This structure has direct control over autonomic functions, often via neurally based reflex arcs
Brain stem
Would lead to bronchodilation
sympathetic nervous system
Activated to speed up heart rate
sympathetic nervous system
Causes widespread vasoconstriction
sympathetic nervous system
The driving force of blood flow is a(n) __________ gradient.
pressure
During the filling of the atria and ventricles
AV valves are open
Order these structures for conveying electrical signals through the heart.
__5__ left and right bundle branches
__7__ ventricular muscle
__1__ sinoatrial node
__3__ atrioventricular node
__6__ Purkinje fibers
__2__ atrial muscle
__4__ bundle of His
Place these structures in the order that blood returning to the heart from the body would pass through.
__6__ lungs
__9__ left atrioventricular valve
__4__ pulmonary semilunar valve
__10__ left ventricle
__2__ right atrioventricular valve
__7__ pulmonary veins
__11__ aortic semiluar valve
__5__ pulmonary arteries
__3__ right ventricle
__1__ right atrium
__8__ left atrium
__12__ aorta
Match the EKG abnormality to it’s underlying malfunction SA node is non functional
Junctional Rhythm
AV node only conducts some of the SA node excitations.
2nd degree heart block
The electrical activity on the heart is completely disorganized and follows no pattern.
Fibrillation
The best definition of end diastolic volume is:
the volume of blood in the ventricles after ventricular relaxation
Which term defines the following: the amount of blood pumped out of the heart each minute
cardiac output
Select all of the following choices that can result in increased contractility
Increased Epinephrine levels and Increased sympathetic activation
Which receptor is responsible for autonomic stimulation causing increased heart rate
beta-1 adrenergic
This structure transmits parasympathetic motor signals to the heart
vagus nerve
Which of the following factors most likely explains lowered end systolic volume
increased myocardial contractility
If you remove autonomic control of the heart from a person at rest, what will happen:
heart rate will slow down
Which of the following best explains the molecular mechanism underlying the Frank-Starling law of the heart.
Increased intracellular calcium in myocardial cells enhances contraction force
Select all of the following choices that can result in increased heart rate
Increased sympathetic activation and Increased Norepinephrine levels
This structure transmits sympathetic motor signals to the heart
cardiac nerve plexus
This structure transmits visceral sensory signals from the heart to the brain
vagus and glossopharyngeal nerves
Which term defines the following: the volume of blood ejected from the heart per beat
stroke volume
Contractility is best defined as
the force of myocardial contraction, independent of end diastolic volume
According to the FRANK-STARLING Law of the Heart:
- Greater ventricular stretch results in greater stroke volume
- Longer myocardial fibers result in more cross bridges which results in greater contractile force
- Greater ventricular end diastolic volume result in greater force of myocardial contraction
*Greater stretch equal more blood expelled
In which situation would the stroke volume be the smallest?
when the difference between the end diastolic volume and the end systolic volume is small
True or False: When using the respiratory pump, decreased intrathoracic pressure helps to lower pressure in the vena cavae resulting in increased venous return.
True
The best definition of end systolic volume is:
the volume of blood in the ventricles after ventricular contraction
Which term defines the following: the amount of blood pumped out of the heart each minute
cardiac output
Select all of the following choices that can result in increased contractility
Increased Epinephrine levels
Increased sympathetic activation
Select all of the following choices that can result in increased stroke volume
Contraction of skeleton muscles surrounding large veins
Increased sympathetic activation
Increased function of the respiratory pump
Constriction of smooth muscle around veins
Increased Epinephrine levels
Select all of the following choices that can result in increased heart rate
Increased sympathetic activation
Increased Norepinephrine levels
Type your answer below. Do not include units.
If the HR is 70 bpm and the SV is 60 mL, the cardiac output would be exactly equal to:
___4200___
In which situation would the stroke volume be the smallest?
when the difference between the end diastolic volume and the end systolic volume is small
Which receptor is responsible for autonomic stimulation causing decreased heart rate
muscarinic
Which receptor is responsible for autonomic stimulation of contractility
beta-1 adrenergic
If capillary hydrostatic pressure is higher than normal, you might expect
increased filtration at capillary beds
The force exerted by plasma proteins helping to pull water towards the blood
colloid osmotic pressure
Body-wide vasodilation occurs because
an decrease in sympathetic output
This type of blood vessel is low pressure and has valves that prevent backwards flow
veins
Baroreceptor for monitoring mean arterial pressure are found in the:
carotid body and aorta
This type of blood vessel has the highest pressure
aorta
Contraction of the smooth muscle surround arterioles results in
vasoconstriction
The blood vessels primarily responsible for total peripheral vascular resistance
arterioles
Which of the following factors influence flow of blood.
blood pressure
blood vessel length
blood viscosity
vascular resistance
blood vessel radius
True or False: Filtration is typically greater than absorption at capillary beds over the course of a day.
True
When tissues are metabolically inactive (at rest):
precapillary sphincters contract, reducing blood flow to the tissue
The force exerted by blood pressure helping to push water out of blood vessels
capillary hydrostatic pressure
When oxygen levels in a tissue drop:
precapillary sphincters relax, increasing blood flow to the tissue
True or False: Filtration and absorption at capillary beds are typically equal over the course of a day.
False
This layer is generally the thickest in the vessel where it if found
vascular smooth muscle
This type of blood vessel has the lowest pressure
vena cava
This type of blood vessels is primarily responsible for generating ‘resistance’.
arterioles
This structures is the open center of blood vessels where blood flows
lumen
This layer is found in all blood vessels
endothelium
Each of the following factors would increase peripheral vascular resistance except one. Identify the exception.
vasodilation
Choose the factor that causes an increase in vascular resistance.
vasoconstriction
In a given day, there is more fluid filtered than absorbed, potentially resulting in a excess of fluid in the interstitial spaces in the body. how does the body prevent this?
the lymphatic system collects excess fluid and returns it to circulation
How do the precapillary sphincters and the vessels they control respond to increased metabolism in the tissues they perfuse?
relax
shunt blood towards the tissue
vasodilate
Increased viscosity results in:
increased vascular resistance and increased blood pressure
Body-wide vasodilation occurs because
an decrease in sympathetic output
If the concentration of albumin is lower than normal, you might expect
increased filtration at capillary beds
Contraction of the smooth muscle surround arterioles results in
vasoconstriction
Increased blood vessel length results in:
increased vascular resistance and increased blood pressure
The autonomic nervous system controls _____ functions
VISCERAL/SUBCONCIOUS
All preganglionic autonomic neurons release _____ at autonomic ganglia
ACETYLCHOLINE
The location of cell bodies of the parasympathetics is:
CRANIOSACRAL
Sympathetic postganglionic neurons release ______ onto target tissues
NOREPINPHRINE/EPINPHRINE
Do postganglionic autonomics have a myelin sheath
NO
Parasympathetic postganglionic neurons release ___ onto target tissues
ACETYLCHOLINE
The adrenal medulla is allied with the SYMPATHETICS and releases these two chemicals as
hormones:_____
NOREPINPHRINE and EPINPHRINE
ADRENERGIC receptors are targets of the sympathetic nervous system and include the
following subtypes:
1) alpha 1
2) alpha 2
3) beta 1
4) beta 2
5) beta 3
______receptors are found in autonomic ganglia while MUSCARINIC receptors are found on
target organs of the parasympathetic ANS
NICOTINIC
T or F: The cerebral cortex can exert conscious control over the autonomic nervous system.
TRUE
Blood leaving the right ventricle passes the ______ valve and then enters the
________trunk and ______ arteries
PULMONARY x3
These two structures CHORDAE TENDINAE and PAPILLARY MUSCLES attach to the
atrioventricular valves and prevent the valve flaps from
VERTING/PUSHING INTO THE ATRIA
The movement of the valves (opening and closing) in the heart is driven by
PRESSURE
Signal from the sinoatrial node reaches the atrioventricular node by traveling through the
ATRIAL MUSCLE
In a second degree heart block, this node fails to fire occasionally
AV
The 2nd heart sounds occurs when:
SEMILUNAR VALVES CLOSE
During the isovolumetric contraction, the valves are:
CLOSED
If left atrial pressure exceeds left ventricular pressure, blood flows from the _____ to the
_____
ATRIUM
VENTRICLE
A heart rate of 80 bpm with a stroke volume of 50 mL/beat would result in a cardiac output of:
4000 mL/min
An increase in end diastolic volume with no change in end systolic volume will result in an
_______in stroke volume
INCREASE
Name the three mechanisms that lead to an increase in venous return:
1) CONTRACTION OF VASCULAR SMOOTH MUSCLE ON VEINS
2) CONTRACTION OF SKELETAL MUSCLE SURROUNDING VEINS
3) RESPIRATORY PUMP
A DECREASE in end systolic volume is achieved by an increase in ______ of the
myocardium. This will increase stroke volume.
CONTRACTILITY
Activation of the ____nervous system will result in increased contractility.
SYMPATHETIC
This ion is KEY in determining the contractile force of the myocardium:
CALCIUM
The myocardium is supplied by the following special circulation:
CORONARY
The _____ circulation supplies the heart muscle while the SYSTEMIC circulation supplies
the rest of the body while the PULMONARY CIRCULATION connects the heart to the lungs..
CORONARY
Name two major differences between arteries and veins
Amount of elastic material and
smooth muscle
The VASO VASORUM supplies blood and nervous connection to blood vessels, particularly the
tunica _____
MEDIA
Most blood vessels are only supplied by this part of the autonomic nervous system:
SYMPATHETIC
Name the three types of capillaries, rank them in terms of flow rate across the endotheliaum
and give one example of a organ where each is found
Continuous – slow, skin/muscle/brain/lungs
Fenestrated – moderate, kidney/intestines/glands
Sinusoid – high, liver/spleen/bone marrow/adrenal medulla
Name the 4 processes by which fluids move across all types of capillaries
DIFFUSION, BULK FLOW (CLEFTS), BULK FLOW (FENSTRATIONS), PINOCYTOSIS
The main force (pressure) driving filtration is
CHP while the main force driving absorption is:
COP
This molecule is responsible for generating most of the osmotic pressure in the blood.
ALBUMIN
A tissue with high levels of oxygen would have blood shunted TOWARDS or AWAY
AWAY
A tissue with high levels of carbon dioxide would have blood shunted TOWARDS or AWAY
TOWARDS
Name three variables that influence peripheral vascular resistance and explain how they do so
Viscosity – high viscosity = increased resistance.
Radius – small diameter = increased resistance
Length – long vessels = increased resistance
True or False: A blood pressue of 150 / 100 is ‘normal
FALSE
Name 5 factors that can cause hypertension. For each, name the physiological mechanism that
links the factor to blood pressure.
Stress – Cardiac Output
Obsesity – vessel length – resistance
Atherosclerosis – reduced vessel diameter – resistance
Diabetes – increased blood viscocity
Volume Overload (several diseases, often renal-realted) – increase total blood volume –
blood pressue