Anatomy Clinical Correlations Flashcards
What is achondroplasia?
Achondroplasia
- A very common (1 in 15 000-40 000 live births) form of dwarfism, characterized by short upper and lower limbs in association with an average-sized trunk
- Caused by mutations in FGFR3
- 80% of cases caused by spontaneous mutations
- Autosomal dominant inheritance
- Mutation inhibits cartilage growth at growth plates of long bones, resulting in shortened limbs
What is syndactyly?
Syndactyly
- Webbing between digist is among the most common birth defects
- Cutaneous syndactyly: interdigital webs do not degenerate
- Osseous syndactyly: digital rays do not separate
What is the clinical period for limb development? What are some teratogens that are dangerous during this time?
Teratogens
- Teartogens acting during key windows of development can cause severe developmental anomalies
- The critical period for limb development is 24-26 days post fertilization
- Thalidomide: used as an anti-nausea agent 1957-1962, resulted in severe limb anomalies
- Phenytoin: anti-convulsant, results in digit hypoplasia
- Warfarin: anti-coagulant, results in shortened fingers and abnormal chondrogenesis
A 20 yr old male presents to the emergency department after a FOOSH. There is pain and swelling at the base of the thumb. On PE the patient is tender over the anatomical snuff box. What bone has the patient most likely fractured?
Scaphoid Fracture
- The scaphoid is often fractured due to FOOSh
- Often misdiagnosied as a sprain, because it can be difficult to see on a radiograph
- Blood supply is poor, so healing may take more than three months
- Necrosis of the fragment may occur
Describe the difference between a shoulder separation and dislocation.
The highly mobile nature of the shoulder makes it easy to injure.
- Shoulder separation: dislocation of the AC joint, often with associated AC and coracoclavicular ligament tear
- Usually results form a direct blow, or FOOSH
- Common in contact sports
- Shoulder dislocation: dislocation of the glenohumeral joint
- Usually antero-inferior displacement
- Often accompanied by capsule tears
What is contained within the carpal tunnel?
Carpal tunnel is formed by the flexor retinaculum, it contains:
- Tendons of the superficial and deep digital flexors
- Flexor digitorum superficialis tendons
- Flexor digitorum profundus tendons
- Flexor pollicis longus tendon
- Flexor carpia radialis tendon
- Median nerve
- Reduction in the size of the carpal tunnel (ex. inflammation of the tendon sheathes) causes pressure on the median n.
What is Erb’s palsy?
Erb’s Palsy
- Superior brachial plexus injury due to excessive stretching of the neck and depression of the shoulder
- Erb’s palsy affects muscles supplied by C5-C6
- Musculocutaneous n.
- Subscapular n.
- Axillary n.
What is Klumpke’s palsy?
The inferior part of the brachial plexus may be injured by excessive stretching of the arm ex. falling from a ladder and grabbing onto something to stop the fall
- This results in Klumpke’s palsy
- May be treated surgically by removing scar tissue and/or inserting nerve grafts
Why is the PCL torn less often than the ACL?
The PCL is shorter and stronger and stronger than the ACL; consequently it is not torn nearly as often as the ACL.
What is the most common MOI of an ankle sprain? What ligament is commonly sprained?
The LCL is weak and often sprained. It resists inversion of the foot. One or more of its parts may tear in the common inversion ankle injury; when this happens, the ligaments usually tear from anterior to posterior, with the anterior talofibular ligament being torn first.
A direct trauma to the head of the fibula in a patient who presents with foot drop (inability to dorsiflex at the ankle) and an inability to dorsiflex the foot suggest inury to what nerve?
Common Fibular N.
This is the most commonly injured nerve of the lower limb. This neve is vulnerable to compression injury, usually from direct trauma, where it wraps around the head of the fibula. When injured, the patient may present with footdrop (inability to dorsiflex at the ankle) and an inability to ever the foot.
Posterior compartment syndrome of the lower leg may result in the injury of which nerve?
Tibial N.
A fracture of the surgical neck of the humerus may injury which nerve?
Axillary N.
A midshaft fracture of the humerus may injur which nerve?
Radial N.
What type of dislocation is most common for the glenohumeral joint? What nerves would be at risk in this injury?
Musculocutaneous N. and Axillary N. may be at risk for injury in an anterior glenohumeral jt dislocation.