Anatomy (CH 5.1a) Exam 2 Deck Flashcards
Epithelium (Epithelial Tissue)
composed of one or more layers of closely packed cells, and it contains little to no extracellular matrix between these cells.
Epithelial tissue covers the…
body surfaces, lines the body cavities and organ cavities, and forms glands.
Cellularity
epithelial tissue is composed of entirely tightly packed cells. There is a minimal amount of extracellular matrix between the cells.
Polarity
An epithelium has an apical surface, which is exposed either to the external environment or to some internal body space. The apical surface may have either microvilli or cilia
Apical Surface
a free or superficial surface related to the tip or extremity of a conical (cone-shaped) or pyramidal structure; opposite of basal.
Basal Surface
a fixed or deep surface where the epithelium is attached to a basement membrane with underlying CT.
Basement Membrane
selective molecular layer that attaches epithelial tissue to underlying CT
The epithelial layer is bound at its…
basal surface to a thin basement membrane; may be seen as a single molecular layer w/light microscopy but actually consists of 3 molecular layers that can be viewed w/ an electron microscope.
The 3 molecular layers of the basement membrane are formed by…
secretions of both the epithelium and the underlying CT, and are composed of collagen, glycoproteins, and proteoglycans
These molecular structures of the basement membrane components act like…
“glue” to strengthen the attachment and form a selective molecular barrier between the epithelium and the underlying CT.
Avascularity
all epithelial tissues lack blood vessels.
Nutrients for epithelial cells are obtained either…
directly across the apical surface or by diffusion across the basal surface from blood vessels within the underlying CT.
Extensive Innervation
epithelia are richly innervated (supplied with nerves) to detect changes in the environment at that body or organ region.
High Regeneration Capacity
epithelial cells undergo cell division frequently. This allows tissue to regenerate itself at a high rate, a necessary condition for a tissue that is often exposed to the environment and lost by abrasion and damage. the continual replacement occurs through cell division of the deepest epithelial cells (called stem cells), which are adjacent to the basement membrane.
Physical Protection
epithelial tissues protect both external and internal surfaces from dehydration, abrasion, and destruction by physical, chemical, or biological agents.
Selective Permeability
Ability of a cell to regulate what can cross a membrane.
An epithelium typically exhibits a range of permeability; it may be…
relatively non-permeable to some substances, while promoting and assisting the passage of other ions and molecules.
All substances that enter or leave the body must pass through
An epithelium. Thus, epithelial tissues act as the body’s “gatekeepers”
Secretions
Some epithelial cells are specialized to produce and release secretions. These cells form glands.
Glands may be individual cells scattered among…
other cell types in an epithelium (goblet cells) or arranged in small, organized clusters within a multicellular gland.
Sensations
conscious perception of a stimulus.
Epithelial tissues are innervated by…
sensory nerve endings to detect or respond to a stimulus. These nerve endings - and those in the underlying CT - continuously relay sensory input to the CNS concerning touch, pressure, temp, and pain.
The classification of each epithelial type is indicated by what two-part names?
First part of the name refers to the number of epithelial cell layers. Second part describes shape of cells at apical surface of epithelium.
Epithelia is classified as either…
simple or stratified
Simple Epithelium
Is one layer of epithelial cells, and all of the epithelial cells are in direct contact with the basement membrane.
A simple epithelium is found in areas where…
stress is minimal and filtration, absorption, or secretion is the primary function.
Stratified Epithelium
Contains two layers of epithelial cells. Only the cells in the deepest (basal) layer are in direct contact with the basement membrane.
Stratified epithelium tissue provides…
either more structural support or better protection for underlying tissue and cells in basal layer continuously regenerate as the cells in the apical layer are lost due to abrasion or stress.
Pseudostratified Epithelium
appears layered (stratified) because the cells’ nuclei are distributed at different levels between the apical and basal surfaces.
We classified pseudostratified epithelium as a type of…
simple epithelium because all of the cells are attached to the basement membrane.
Squamous Cells
flat, wide, and somewhat irregular in shape (think egg yolk).
Cuboidal Cells
are about as tall as they are wide; do not resemble perfect cubes because their edges are somewhat rounded; cell nucleus is spherical and located within center of the cell.
Columnar Cells
slender and taller than they are wide; cell nucleus is oval and usually oriented lengthwise and in basal region of cell.
Transitional Cells
can change their shape from polyhedral to more flattened, depending on degree to which epithelium is stretched.
Shape change occurs in transitional cells when…
epithelium cycles between distended and relaxed states, such as lining of the bladder, which fills with urine and is later emptied.