Anatomy: Breast Cancer Flashcards
1
Q
What are the 2 premalignant lesions of the breast
A
DCIS = ductal carcinoma in situ
LCIS =lobular carcinoma in situ
2
Q
What are the 3 invasive types of breast cancer?
A
- ductal
- lobular
- tubular
3
Q
What are the 4 molecular subtypes of breast cavern
A
- basal (BRCA1/triple negative)
- luminal A (ER)
- luminal B (ER and HER2)
- HER2
4
Q
What is the arterial supply of the breast?
A
Laterally = lateral thoracic artery from axillary Medially = internal thoracic artery from subclavian
5
Q
What is the venous drainage of the breast?
A
Laterally = lateral thoracic vein from axillary Medially = internal thoracic vein from subclavian
6
Q
Where does breast cancer locally spread to?
A
- breast lies in superficial fascia overlying pectorals and ribs 2-6
- lung or pleural cavity
7
Q
What is the lymphatic drainage of the breast?
A
- superficial and lateral aspects –> axillary nodes (apical, central, lateral, pectoral_
- medial aspect = parasternal nodes
- inferior aspect = abdomen
