Anatomy And Histology II Flashcards
The indifferent gonad stage lasts
7-10 days
The germ cell number has increased to approximately 10,000 by
The indifferent gonad stage
Gonadal differentiation is directed by
a genetic program involving hundreds of genes initiated in the indifferent gonad
Oogonial proliferation and oocyte formation requires expression of the
WNT4 and RSPO1 genes
WNT4 and RSPO1 genes activate the
beta-catenin signaling pathway leading to loss of cell-cell adhesion between the female germ cells thus allowing them to enter meiosis
In the male the Sry gene inhibits
The Wnt4 gene expression in the indifferent gonad and promotes the male sexual development program
In the female fetus the wolffian duct
regresses and the müllerian duct differentiates in a cranial to caudal (head to tail) direction into oviduct, uterus , cervix, and upper third of the vagina
The developmental processes that occur to bring about this organogenesis are under what control?
The control of steroid hormones that regulate key developmental genes.
The major organs of the female reproductive system include:
Genital Tract, Ovaries, pituitary