Anatomy Flashcards

1
Q

What are the vertebral ligaments?

A

Anterior longitudinal ligament

  • adheres to anterior surface of vertebral bodies and discs, runs from C2 to sacrum

Posterior longitudinal ligament

  • extends along posterior aspect of the vertebral bodies and discs

Ligamentum flavum

  • connects adjacent vertebral laminae
  • thick elastic fibres are more developed in lumbar than thoracic regions

Interspinous ligaments

  • connect adjacent spinous processes

Supraspinous ligaments

  • a tough, fibrous ligament that attaches tips of spinous processes from C7 to sacrum
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2
Q

What are the meninges?

A

The three membranes surrounding the brain and spinal cord

  • dura mater
  • arachnoid mater
  • pia mater

They’re separated from the periosteum by the epidural space

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3
Q

What does the epidural space contain?

A
  • lymphatics
  • spinal nerve roots
  • loose fatty tissue
  • small arteries
  • network of large, thin walled blood vessels called the epidural venous plexus
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4
Q

What are the boundaries of epidural space?

A

Superior - foramen magnum

Inferior - sacrococcygeal membrane

Anterior - posterior longitudinal ligaments and the vertebral bodies

Posterior - ligamentum flavum and vertebral laminae

Lateral - pedicles and intervertebral foraminae

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5
Q

What is the subarachnoid space?

A
  • spinal or intrathecal space
  • space between the arachnoid mater, which lines the dural sheath and the pia mater
  • contains CSF
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6
Q

What afferent fibres does the pain of labour and delivery affect?

A

Afferent fibres from T10 to L4.

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7
Q

For C-Section, what sections of the spinal cord needs to be blocked?

A

T10 to S5 is necessary

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8
Q

What are the characteristics of a Tuohy needle?

A
  • 8cm shaft, 2.5cm hub
  • 1cm markings
  • 16 or 18G
  • snap on wings
  • curved blunt tip - Huber point, exit hole at 20° to shaft
  • stylet introducer to prevent coring of tissues
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9
Q

What are the characteristics of the loss of resistance syringe?

A
  • low resistance plunger
  • plasic single use
  • can be used with saline or air to detect LOR
  • graduated barrel
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10
Q

What are the characteristics of an epidural catheter?

A
  • narrower than the corresponding epidural needle
  • 90cm long, transparent flexible tube
  • biologically inert
  • standardized markings
    • single at tip
    • 1cm from 5 - 14cm
    • double marking at 10cm
    • triple at 15cm
    • quadruple 20cm
  • distal end has multiple side holes with a closed smooth tip to minimize risk of dural or vascular puncture
  • proximal end attaches to Luer lock and filter
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11
Q

What are the characteristics of the epidural filter?

A
  • luer lock connections to epidural catheter and infusion set
  • 0.22 micrometre hydrophilic two-way filter for bacteria/viruses/glass
  • transparent
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12
Q

What are the characteristics of a spinal needle?

A
  • used for intrathecal injection of drugs and sampling CSF
  • transparent hub for early identification of CSF
  • 18-32 Gauge available, 25G most common
  • 9 or 10cm length is most common
  • cutting bevel (Yale/quincke) or blunt (whitacre/sprotte)
  • stylet to prevent coring and strengthen shaft
  • Introducer for 25G and finer needles
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13
Q

What local anaesthetics are licensed from obstetric epidural and spinal use?

A

Bupivacaine, levobupivacaine, ropivacaine and lidocaine are all licensed for obstetric epidural use, whilst hyperbaric bupivacaine is the only local anaesthetic licensed for obstetric spinal use.

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14
Q

How do local anaesthetics work?

A

Bind to voltage-gated sodium channels in the nerve cell membranes slowing depolarization and inhibiting conduction in nerve fibres transmitting painful stimuli to the spinal cord.

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15
Q

How does increasing lipid solubility affect potency of local anaesthetics?

A

Increasing lipid solubility allows more rapid penetration of nerve cell membrane and therefore greater potency

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16
Q

What is the duration of action of local anaesthetic dependent on?

A

To the degree of protein binding.

Bupivacaine, levobupivacaine and ropivacaine are approximately 95% protein-bound and therefore have a longer duration of action than lidocaine, which is approximately 65% protein-bound.

17
Q

What is the speed of onset of local anaesthetic dependent on?

A

The degree of ionization, which is dependent on the pKa of the drug (it’s the non-ionized form of the local anaesthetic which diffuses across the nerve sheath)

Bupivacaine, levobupivacaine and ropivacaine have a pKa of 8.2. They are therefore more ionized and have a slower onset of action at body pH than lidocaine, which has a pKa of 7.7.

18
Q

Why are opioids used in epidural/spinal anaesthesia?

A
  • they enhance quality of analgesia
  • reduce mass of local anaesthetic required
  • reduce motor block produced in epidurals
  • enhance surgical anaesthesia
  • postop analgesia
19
Q

What is the action of opioids in epidurals?

A

Bind to opioid receptors in the substantia gelatinosa of the spinal cord. They have to penetrate the dura first.

Speed of penetration increases with lipid solubility +