Anatomy Flashcards
What is the function of arteries, capillaries and veins?
Arteries = take blood away from the heart Capillaries = exchange nutrients Veins = collect and return blood to heart
What is the function of the lymphatics?
Drain excess extracellular fluid from tissues - blood goes into tissues and plasma leaks out of capillaries into ECF - lymphatic channels return this ‘lymph’ to the venous circulation
What splits into the right and left pulmonary artery?
Pulmonary trunk
Where does the inferior mediastinum begin and what is it split into?
T4 - sternal angle
Anterior, middle and posterior
What is contained within the middle mediastinum?
Heart, origins of the great vessels
Where is the mediastinum found?
Between the 2 pleural cavities
What is the function of the azygos vein?
Transports deoxygenated blood from the posterior walls of the thorax and abdomen into the superior vena cava - it enters the vena cava at T4
What does the heart sit on top of?
The diaphragm
What are the 3 parts to the aorta and what is their vertebral levels?
Ascending Aortic arch (begins and ends at T4) Descending (descends from T4 downwards - thoracic then abdominal aorta)
What are the two main circulations?
Pulmonary and systemic
What vertebral level does the pulmonary trunk split?
T4
How many vessels enter the LA posteriorly?
2 left and 2 right pulmonary veins
What drains into the RA?
Superior and inferior vena cava (one single channel)
Does the right side of the heart face the front or back?
Right side of the heart faces the front and left faces the back
What are the coronary arteries?
Surround the heart on the surface (pericardium) and dive into the myocardium and feed it with oxygenated blood
What are the three branches that come of the aortic arch?
Brachiocephalic trunk - right subclavian artery and right common carotid artery
Left common carotid
Left subclavian artery
What does ‘common’ mean?
That its going to split - e.g. common carotid splits into external and internal carotid artery (the external carotid supplies the face and the internal carotid supplies the brain), common illiac splits into internal and external illiac artery (external illiac goes onto form the femoral artery)
What lies at the base (back) of the heart?
LA (and the LV)
Where does the apex beat lie?
Mid-clavicular line, 5th intercostal space (just below nipples)
What chamber makes up the apex?
LV
Where does the trachea bifurcate?
T4
In a cross section through the chest, what will you find?
The thoracic cavity contains principally two pleural cavities with, between them, the mediastinum
What chamber is most anterior in a cross section of the thorax?
RV
What chamber is most posterior in a cross section of the thorax?
LA
what way does the apex point in a cross section of the thorax?
Into the left lung (top right hand corner)
Where is the RA located?
It is the most right part of the heart
What structures sit behind the LA?
The LA is entirely posterior
Oesophagus
Descending aorta
Azygos vein
Where is the thymus located?
Just below the sternum
When lying down, what vertebral levels does the heart lie between?
T5-T8
What is located in the anterior mediastinum?
Sternum and costal cartilages 4-7
Anterior edges of lungs and pleura
Thymic remnants
Internal thoracic vessels
What is located in the posterior mediastinum?
Oesophagus Descending aorta Thoracic vertebrae 5-8 (middle as there is 12) Sympathetic chain Azygos vein
What is located laterally to the heart?
Lungs
Phrenic nerve
What is located inferiorly to the heart?
Central tendon of diaphragm
What is located in the superior mediastinum?
Trachea Oesophagus Vagus and phrenic nerve SVC Left and right brachiocephalic veins (form left and right subclavian veins) Internal jugular vein Common carotid artery
What are the layers of the heart from inside to outside?
Endocardium Myocardium Epicardium (visceral layer of serous pericardium) Pericardial cavity Parietal layer of serous pericardium Fibrous pericardium
What is another name for the epicardium?
Pericardium
What is the endocardium?
Simple squamous epithelium sitting on a basement membrane, sitting on connective tissue
What is the myocardium made up of?
Cardiac muscle
What is the epicardium?
Outer layer of the heart wall
Simple squamous epithelium (outermost layer) + BM + connective tissue
What forms the heart valves and lines the heart chambers?
Endocardium
What are myocytes connected by?
Intercalated discs
What is the thickest layer of the heart wall?
Myocardium
What is a functional syncytium?
All the cells function as a unit
What is the most outer layer of the heart?
Fibrous pericardium
What is the fibrous pericardium fused with?
The central tendon of the diaphragm
What is the function of the fibrous pericardium?
Holds the heart in place and protects the heart against sudden overfilling
What pierces the fibrous pericardium?
The aorta, pulmonary trunk and the SVC
The tunica adventitia of these vessels becomes fused with the fibrous pericardium
What is the direction of blood flow in the heart controlled by?
Valves - they work passively
What is located on the right border of the heart?
Right atrium
What is located on the inferior border of the heart?
Right and left ventricle
What is the function of the chordae tendineae and papillary muscles?
Prevent valve failure (prevents inverting)
What are some clinically important valve scenarios?
Abnormalities - incompetence/stenosis
Infection (bacterial endocarditis)
What valve is bicuspid?
Mitral valve (LA -> LV)
2 cusps =
2 papillary muscles and 2 sets of chordae tendinae
What are the types of atrio-ventricular valves?
Tricuspid and bicuspid valves
What are the semi-lunar valves?
Aortic and pulmonary valves
What is the fibrous cardiac skeleton?
Anchors the valves if the heart - consists of four fibrous rings each surrounding one of the valves
What is the function of the fibrous cardiac skeleton?
Provides and semi-rigid support for the valve leaflets
What is the fibrous cardiac skeleton made up of and where does it lie?
Dense connective tissue
The plane between the atria and the ventricles
What arises from the right aortic sinus?
Right coronary artery
What arises from the middle aortic sinus?
Left coronary artery
Why are the coronary arteries only perfused in diastole?
Because in systole, aortic sinuses are shielded by aortic valve cusps
Where are the coronary arteries located?
In the epicardium
What happens if a coronary artery is blocked?
Heart attack
What does the right coronary artery split into?
Right marginal artery
Posterior descending artery
What does the left coronary artery split into?
Left anterior descending (or inter-ventricular) artery
Left marginal artery
Left circumflex artery
Whats different about the right and left coronary arteries?
The left coronary artery splits into 2 and the right just stays as 1
What is an important function of the serous pericardium?
Secretes fluid into the pericardial space - lubricant which allows the heart to move (i.e. in diastole allows the heart to stretch)
What are the two types of arteries?
Elastic artery - lots of elastic fibres
Muscular artery - more smooth muscle
What do arterioles contain and why is this important to them?
Smooth muscle - this allows them to expand and contract to control blood flow to capillary bed
What is the order, starting from the aorta, back round to the VC?
Aorta Arteries Arterioles Capillaries Venules Veins Vena cava
What are the the layers of an artery wall?
Tunica intima Tunica media Tunica adventitia (externa)
What is the tunica intima made up of?
Epithelium (simple squamous) + BM + connective tissue
What is the tunica media made up of?
Smooth muscle
Elastic tissue
What is the tunica externa made up of?
Fibrous connective tissue