Anatomy Flashcards
What are the layers of the gut wall?
Mucosa (innermost)
Submucosa = dense CT, blood vessels, lymphoid tissue, Meissner plexus
External muscle layers = auerbach plexus
Serosa (outermost) = blood/lymph vessels
What are the layers of the mucosa?
Epithelium = facilitate transport, absorption, hormones, mucus
Lamina propria = lymphoid nodes, IgA
Muscularis mucosae = smooth muscle
What epithelia type lines the gut?
Stratified squamous = beginning and end of gut
When secretion/absorption is needed = simple columnar
What is an enterocyte?
Simple columnar cell that has been specialised for absorption
Microvilli = brush border (contains enzymes)
What is a goblet cell?
Scattered between enterocytes
Prod mucus = lubrication, resist acid (HCO3), protection, food source for bacteria
What are foveolar cells?
Line gastric mucosa/pits
Secrete mucus/HCO3
How does the GI tract achieve such a large surface area?
Permanent folds
Villi
Microvilli
Crypts
What happens when the bowel becomes perforated?
Spill into the peritoneal cavity
Highly acidic
Infection
What is the role of stem cells in the GI tract?
Reside in crypts
Constantly divide to replace epithelia
Outline paneth cells
Base of crypts
Secrete anti-bacterial proteins
Describe enteroendocrine cells in the gut
Deep in crypts
Secrete = gastrin, CCK, secretin
Define cryptitis
Inflam of gut wall
Define crypt abscess
Presence of neutrophils in gut lumen
How is exocrine glandular tissue in the gut organised?
Acini = serous secretions and enzymes
Tubules = secrete mucous
E.g. Salivary, pancreas
Define ulceration
Erosion through muscularis mucosae