Anatomy Flashcards
what does the CNS consist of?
brain + spinal cord
what does the PNS consist of?
12 pairs cranial nerves
31 pairs spinal nerves + branches
which cranial nerve is thought to be almost part of the CNS?
optic nerve CN II
in the early stages of brain development, what are the 3 visible swellings in the neural tube?
prosencephalon
mesencephalon
rhombencephalon
will the prosencephalon become forebrain, midbrain or hindbrain?
forebrain
will the mesencephalon become forebrain, midbrain or hindbrain?
midbrain
will the rhombencephalon become forebrain, midbrain or hindbrain?
hindbrain
what major embryonic divisions does the prosencephalon divide into?
telencephalon
diencephalon
what major embryonic divisions does the rhombencephalon divide into?
metencephalon
myelencephalon
what does the telencephalon correspond to in the mature brain?
cerebral hemispheres
what does the diencephalon correspond to in the mature brain?
thalamus and hypothalamus
what does the mesencephalon correspond to in the mature brain?
midbrain
what does the metencephalon correspond to in the mature brain?
pons and cerebellum
what does the myelencephalon correspond to in the mature brain?
medulla oblongata
apart from the visible swellings, what does the remainder of the neural tube become?
spinal cord
what makes up the brainstem?
midbrain
pons
medulla oblongata
what are the supporting cells in the CNS called?
glial cells
what are the 4 types of glial cells in the CNS?
astrocytes
oligodendrocytes
microglia
ependymal cells
what are the 3 main roles of an astrocyte in the CNS?
- physical support
- instigates tight capillaries for blood brain barrier
- environmental homeostasis
what is the function of oligodendrocytes in the CNS?
produce myelin in the CNS
what cranial nerve is the odd one out because it is myelinated by oligodendrocytes instead of schwann cells?
CN II optic nerve
what is the function of microglia in the CNS?
immune monitoring and antigen presentation (phagocytes)
where are microglia produced?
bone marrow
what MHC class do microglia epress?
MHC II
what is the function of ependymal cells in the CNS?
ciliated cuboidal/columnar epithelium that lines the ventricles
what are deep sulci in the brain called?
fissures
in the cerebellum, what is the name for the bumps that are equivalent to gyri in the cerebrum?
fovia (singular = fovium)
what is the name of the deep sulcus at the anterior sagittal midline of the brain?
longitudinal fissure (or interhemispheric fissure)
is grey matter generally located peripherally or centrally in the brain?
generally peripherally
does grey matter contain cell bodies or axons?
cell bodies
does white matter contain cell bodies or axons?
axons
what is the function of sulci and gyri?
allow us to incorporate a lot of grey matter in a small space
is grey matter located peripherally or centrally in the spinal cord?
centrally
what is the name of the sulcus at the coronal midline of the brain?
central sulcus
anterior to the central sulcus, what is the gyrus called?
precentral gyrus
posterior to the central sulcus, what is the gyrus called?
postcentral gyrus
what is the name of the sulcus between the frontal or parietal lobe and temporal lobe?
lateral fissure
what is the name of the dura sheet which occupies the longitudinal fissure?
falx cerebri
what is the corpus callosum?
white matter that carries information from one cerebral hemisphere to the other
what sulcus separates the occipital lobe from the parietal lobe?
parieto-occipital sulcus
the primary visual cortex surrounds what sulcus?
calcarine sulcus
what connects both parts of the thalamus at their medial aspect?
interthalamic adhesion
what sulcus divides the pareital lbe and the frontal lobe?
central sulcus
what is the deep lobe of the brain?
insular lobe (insula)
what are the 3 layers of meninges from superficial to deep?
dura mater
arachnoid mater
pia mater
what does the subarachnoid space contain?
CSF
what does the dura adhere to?
the inner periosteum of the skull bones
which meningeal layer(s) coats the brain in every sulcus and gyrus?
pia mater
dura and arachnoid are wrapped around but do not go into the sulci
where does the 3rd ventricle lie?
between both parts of the thalamus in the diencephalon
where does the 4th ventricle lie?
between the cerebellum and the pons
what connects the lateral ventricles to the 3rd ventricle?
interventricula foramen of Monro
what connects the 3rd ventrcile to the 4th ventricle?
cerebral aqueduct
in what 2 plexuses is the enteric nervous system found?
myenteric plexus
submucosal plexus
the dural venous sinuses drain into what vein?
internal jugular vein
where is the cell body of multipolar cells? (eg skeletal muscle cell)
central nervous system
where is the cell body of pseudounipolar cells? (eg sensory)
peripheral nervous system
where are upper motor neurones located?
CNS
where are lower motor neurones located?
PNS
in the CNS, what is a collection of nerve cell bodies called?
nucleus
in the PNS what is a collection of nerve cell bodies called?
ganglion
in the CNS what is a bundle of axons called?
tract
in the PNS what is a bundle of axns called?
nerve
compare tracts (CNS axon bundle) and nerves (PNS axon bundle) in terms of modality?
tracts are usually single modality (eg motor tract)
nerves a can be mixed (eg spinal nerves)
what is the modality of CN I? (olfactory)
special sensory
what is the modality of CN II? (optic)
special sensory
what is the modality of CN III? (oculomotor)
somatic motor and parasympathetic
what is the modality of CN IV? (trochlear)
somatic motor
what is the modality of CN V? (trigeminal)
somatic motor (V3) and somatic sensory
what is the modality of CN VI? (abducens)
somatic motor
what is the modality of CN VII? (facial)
somatic motor, special sensory and parasympathetic
what is the modality of CN VIII? (vestibulocochlear)
special sensory
what is the modality of CN IX? (glossopharyngeal)
somatic sensory, special sensory, somatic motor and parasympathetic
what is the modality of the CN X? (vagus)
somatic motor, somatic sensory and parasympathetic
what is the modailty of CN XI? (spinal accessory)
somatic motor
what is the modality of CN XII? (hypoglossal)
somatic motor
all cranial nerves are associated with the brainstam (midbrain, pons and medulla) except which?
CN I and CN II
describe the 31 pairs of spinal nerves?
C1-C8 T1-T12 L1-L5 S1-S5 Co1
in which forminae are the spinal nerves located?
intervertebral foramina
describe the pathway of sensory axons from the spinal nerve to the dorsal horn?
spinal nerve
posterior root
posterior rootlet
dorsal horn
describe the pathway of motor axons from the ventral horn to the spinal nerve?
ventral horn
anterior root
ventral rootlet
spinal nerve
where does the spinothalamic tract decussate?
in spinal cord, at/a few levels above point of entry
where does the corticospinal tract decussate?
in medullary pyramid
where does the dorsal column lateral meniscus decussate?
in the brainstem
where is the primary afferent neurone of the sensory pathway located?
PNS
where is the second order neurone of the sensory pathway located?
CNS
where does the second order neurone of the sensory pathway synapse?
at the thalamus
where does the third order neurone of the sensory pathway synapse?
cerebral cortex
what dermatome supplies the shoulder?
C4
what dermatome supplies the lateral arm?
C5
what dermatome supplies the lateral forearm to thumb?
C6
what dermatome supplies the middle finger?
C7
what dermatoms supplies the pinky finger?
C8
what dermatome supplies the medial forearm?
T1
what dermatome supplies the medial arm?
T2
what dermatome supplies the nipple?
T4
what dermatome supplies the umbilicus?
T10
what dermatome supplies the area of your jean pockets? (groin)
L1
what dermatome supplies the anterior thigh?
L2
what dermatome supplies the medial thigh and anterior knee?
L3
what dermatome supplies the lateral leg?
L5
what dermatome supplies the medial leg?
L4
what dermatome supplies the lateral foot?
S1
what dermaome supplies the dorsum of the foot?
L5
what dermatome supplies the heel?
S1
what dermatome supplies the posterior knee?
S2
what dermatome supplies the posterior thigh?
S2
what dermatome supplies the buttocks?
S3
what dermatome map is used in dundee?
foerster map
what dermatomes supplies the posterior scalp, neck and shoulder?
C2-C4
what dermatomes supplies the upper limb?
C5-T1
what dermatome supply the lower limb, gluteal region and perineum?
L2-Co1
are nerve plexuses made of anterior or posterior rami?
anterior rami
what makes up the cervical plexus?
C1-C4 anterior rami
what does the cervical plexus supply?
posterior scalp, neck and diaphragm
what makes up the brachial plexus?
C5-T1 anterior rami
what does the brachial plexus supply?
upper limb
what makes up the lumbar plexus?
L1-L4
what does the lumbar plexus supply?
lower limb
what makes up the sacral plexus?
L5-S4
what does the sacral plexus supply?
lower limb, gluteal region and perineum
are dermatomes supplied by anterior or posterior rami of that spinal nerve?
both anterior and posterior rami
are myotomes supplied by anterior or posterior rami of that spinal nerve?
both
which spinal nerves comntain sympathetic outflow?
T1-L2
what horn of the spinal cord do sympathetic neurones leave from?
lateral horn
which segments of the spine have lateral horns?
T1-L2
where do sympathetic presynaptic axons which supply the heart synapse?
in cervical or T1 paravertebral ganglia
how do sympathetic postsynaptic axons travel from paravertebral gangla to the heart?
in cardiopulmonary splanchnic nerves
where do sympathetic -presynaptic axons which supply the lungs synapse?
upper thoracic paravertebral ganglia
how do sympathetic postsynaptic axons travel from the paravertebral ganglia to the lungs?
in cardiopulmonary splanchnic nerves
where do sympathetic presynaptic axons which supply the abdominopelvic organs synapse?
pass through paravertebral ganglia without synapsing and instead synapse with preverebtral ganglia (midline of abdominal aorta ie coeliac ganglia, superior mesenteric ganglion etc)
where do sympathetic presynaptic axons which supply the adrenal medulla synapse?
directly on adrenaline secreting cells of adrenal medulla
in horners syndrome, why is there ptosis?
loss of sympathetic supply to levator palpebrae superioris
in horners syndrome, why is there miosis?
loss of sympathetic supply to dilator pupillae?
in horners syndrome why is there reduced sweating of ipsilateral facial skin?
loss of sympathetic supply to skin sweat glands
what ganglion is associated with the parasympathetic supply of CN III?
ciliary ganglion (eye)
what ganglion is associated with the parasympathetic supply of CN VII?
pterygopalatine ganglion (lacrimal gland) submandibular ganglion (submandibular and sublingual gland)
what ganglion is associated with the parasympathetic supply of CN IX?
otic ganglion (parotid gland)
what ganglion is associated with the parasympathetic supply of CN X?
no associated ganglion
what ganglion is associated with parasympathetic supply from the sacral spinal nerves?
no associated ganglion
what is the tapered cone-shaped end of the spinal cord called?
conus medullaris
what is the name of the tfibrous cord which anchors the conus medullaris to the coccyx?
filum terminale
what is the filum terminale mainly made of?
pia mater
what ligaments suspends the spinal cord within the subarachnoid space?
denticulate ligaments
what are the denticulate ligaments made of?
pia and arachnoid mater
what are the 3 main components of the arterial supply of the spinal cord?
- 3 major longitudinal arteries
- segmental arteries
- radicular arteries
is the epidural space present in the brain or the spinal cord?
only in spinal cord
what is the epidural space between?
periosteum and dura mater
what does the epidural space contain?
adipose tissue and anterior and posterior epidural venus plexuses
where is the primary somatosensory cortex located?
post-central gyrus
how many neurones are involved in the sensory pathway?
3
where is the primary motor cortex located?
pre-central gyrus
where does the lateral corticospinatal tract cross?
pyramids of the medulla
crossed fibres
where does the anterior corticospinal tract cross?
segmentally
uncrossed fibres
in decorticate posturing, what happens to the upper limbs?
hyperflexion
-spastic paralysis
what is the function of the tectospinal tract? (extrapyramidal tract)
reflex head and neck movement to visual stimuli
what is the function of the reticulospinal tract? (extrapyramidal)
fibres from the medulla facilitate flexor movement/inhibit extensor movement
fibres from the pons facilitate extensor movement/inhibit flexor movement
what is the function of the vestibulospinal tract? (Extrapyramidal tract)
excitatory input to antigravity muscles (mainly extensors)
what is unusual about the vestibulospinal tract compared to other pyramidal/extrapyramidal tracts?
doesn’t ever cross to the other side
what are the 3 main extrapyramidal tracts?
rectospinal
vestibulospinal
tectospinal
what is the one sensory modality which doesnt have to access the cortex via the thalamus?
smell