anatomy Flashcards
- Located in the cortex
- The function is to effect small adjustments to achieve electrolyte and acid-base homeostasis
DCT
- Formed by two or more DCT as they pass back down through the cortex and the medulla to collect the urine that drains from each nephron.
- eventually merge and empty their contents into the renal pelvis
CT
(?) mL of blood that the kidneys receive each minute
1200-1500
The regulation of (?) is controlled by the same forces that regulate sodium
chloride
- a major intracellular cation, is important as an enzymatic cofactor.
- The ionized fraction is easily filtered by the glomerulus and reabsorbed in the tubules under the influence of PTH.
magnesium
- Small (?) are readily reabsorbed and may need to be excreted
- Excess hydrogen ions not needed to return filtered bicarbonate are excreted as (?)
- hydrogen ions
- H2PO4
- Located in the cortex
- Return the bulk of each valuable substance back to the blood circulation.
- Secrete products of kidney tubular cell metabolism, such as hydrogen ions, and drugs, such as penicillin.
PCT
- synthesize renin, erythropoietin, 1,25 dihydroxy vitamin D3, and the prostaglandins.
- It is both a primary endocrine site, as the producer of its own hormones, and a secondary site, as the target locus for hormones manufactured by other endocrine organs
kidney
- a peptide hormone secreted by the posterior pituitary, mainly in response to increased blood osmolality;
- also released when blood volume decreases by more than 5%–10%.
ADH
- produced by the adrenal cortex under the influence of the renin–angiotensin mechanism.
- Its secretion is triggered by decreased blood flow or blood pressure in the afferent renal arteriole and by decreased plasma sodium
aldosterone
a basin-like cavity at the upper end of the ureter into which newly formed urine passes
pelvis
- occurs in higher concentrations in the intracellular than in the extracellular fluid environments;
- homeostatic balance is chiefly determined by proximal tubular reabsorption under the control of parathyroid hormone (PTH)
phosphate
(?) encloses each kidney
fibrous capsule
are thick-walled canals, connecting the kidneys to the urinary bladder
ureters
Both the distal convoluted tubule and the collecting ducts can reabsorb and excrete (?), and this excretion is controlled by (?)
- potassium
- aldosterone
- are waste products formed in the body as a result of the degradative metabolism of nucleic acids, amino acids, and proteins.
- Excretion of these compounds is an important function of the kidneys.
- The three principal compounds are urea, creatinine, and uric acid
NPN
- A capillary tuft surrounded by the expanded end of a renal tubule known as Bowman’s capsule.
- Supplied by an afferent arteriole carrying the blood in and an efferent arteriole carrying the blood out.
- The efferent arteriole branches into peritubular capillaries that supply the tubule
glomerulus
- Secretion of (?) prevents excretion of HCO3
- Filtered bicarbonate is returned to the (?)
- 100% reabsorption of filtered bicarbonate at the (?)
- H+
- plasma
- PCT
normal blood osmolality
275-295 mOsm/kg
- the primary extracellular cation in the human body and is excreted principally through the kidneys.
- balance in the body is controlled only through excretion
sodium
- Composed of the thin descending limb, which spans the medulla, and the ascending limb.
- Countercurrent Multiplier System.
- Located in the medulla and the cortex.
- Composed of a region that is thin & thick.
LH
- Ammonia (NH3) is produced and secreted by the (?)
- H+ combines to form (?) that cannot be reabsorbed
- Additional ammonia is produced from the metabolism of glutamine in the (?)
- DCT
- NH4+
- PCT
Water Balance:
* Regulated by the hormone (?).
- (?) responds primarily to changes in osmolality and intravascular volume.
- Increased plasma osmolality or decreased intravascular volume stimulates secretion of (?) from the posterior pituitary
ADH
- the main intracellular cation in the body.
- The precise regulation of its concentration is of extreme importance to cellular metabolism and is controlled chiefly by renal means
potassium
- renal threshold
- A process when substances move from the tubular lumen to the peritubular capillary plasma.
- With the exception of water and chloride ions, the process is active; that is, the tubular epithelial cells use energy to bind and transport the substances across the plasma membrane to the blood
tubular reabsorption
- describes the movement of substances from peritubular capillary plasma to the tubular lumen.
- describes when tubule cells secrete products of their own cellular metabolism into the filtrate in the tubular lumen.
- Transport across the membrane of the cell is again either active or passive
tubular secretion
The PTH- and calcitonin-controlled regulation of (?) absorption from the gut and bone stores is more important than renal secretion or reabsorption
calcium
Urine is temporarily stored in the (?) until voided by way of (?)
- bladder
- urethra
- The glomerulus filters out (?) mL of an essentially protein free, cell-free fluid, called glomerular filtrate.
- The volume of blood filtered per minute is the (?)
- 125-130
- glomerular filtration rate (GFR)
Large decreases of (?) will stimulate ADH secretion even when plasma osmolality is decreased. ADH stimulates (?)
- blood volume
- water reabsorption
Aldosterone stimulates (?) in the distal tubules and (?) and (?) secretion
- sodium reabsorption
- potassium
- hydrogen ion