Anatomy Flashcards
What are the functions of skin?
- an essential barrier between the external environment and the internal body contents
- it protects against mechanical, chemical, osmotic, thermal and UV damage and microbial invasion
- a role in the synthesis of vit D
- regulation of temperature
- psychosexual communication
- a major sensory organ for touch, pain, temperature and other stimuli
What is glabrous skin?
Thick skin round over the palms, soles of the feet and flexor surfaces of the fingers that is free of hair
How many layers of the skin are there and what are they?
- epidermis
- dermis
- hypodermis
What is the epidermis made up of?
Largely layers of keratinocytes
Non-keratinocytes
* melanocytes
* landerhans cells
* merkel cells
What is cornification?
Keratinocytes undergoing terminal maturation - this involves keratin production and migration towards the external surface, a process called cornification
What is the role of melanocytes?
They are responsible or melanin production and pigment formation
What is a Langerhans cell?
It is an antigen-presenting dendritic cell
What are Merkel cells?
sensory mechanoreceptors
What are the layers of the epidermis and what happens in them?
From deepest to superficial:
Stratum basale - mitosis of keratinocytes occurs here
Stratum spinosum - keratinocytes are joined by tight intercellular junctions ‘desmosomes’
Stratum granulosum - cells secrete lipids and waterproofing molecules in this layer
Stratum lucidem - cells lose nuclei and drastically increase keratin production
Stratum corneum - cells lose all organelles but continue to produce keratin
Brownie Spoons Get Licked Constantly
How is the dermis bound to the epidermis?
Through a highly corrugated dermo-epithelial junction
How many layers does the dermis have and what are they?
- Superficial papillary layer
- Deeper thicker reticular layer
What are the cell types and structures found in the dermis and what are their functions?
- Fibroblasts these cells synthesise the extracellular matrix (collagen and elastin)
- Mast cells histamine granule-containing cells of the innate immune system
- Bloods vessels and cutaneous sensory nerves
- Skin appendages hair follices, nails, sebaceouns and sweat glands
What is a pilosebaceous unit?
A combination of the hair follicles and a sweat gland
How do sebaceous cysts release their glandular secretions?
Via a holocrine mechanism into the hair follicle shaft.
What are the two types of sweat gland and how are they different?
- Eccrine glands the main sweat gland of the body, releases a clear odourless substance, comprised of sodium and water for thermoregulation
- Apocrine glands larger sweat glands, located in the axillary and genital regions, the products can be broken down by cutaneous microbes, producing body odour
What is the hypodermis made of and what is it’s function?
It is a major store of adipose tissue, so can vary in size depending on the person
What is hair made of?
Hair is a keratinous filament growing out of the epidermis. It is primarily made of dead, keratinised cells
What is the hair shaft?
The part of the hair not anchored to the follicle, mostly exposed at the skin surface
What makes up the hair bulb?
The hair root ends deep in the dermis at the hair bulb and includes a layer of mitotically active basal cells called the hair matrix. The hair bulb surrounds the hair papilla, which is made of connective tissue and contains blood capillaries and nerve endings from the dermis
What are the layers of the hair?
- Medulla forms the central core
- Cortex a layer of compressed keratinised cells
- Cuticle an outer later of very hard, keratinised cells
What are the three different types of muscle and how are they different?
- Skeletal striated muscle that is under voluntary control from the somatic nervous system - identifying features are cylindrical cells and multiple peripheral nuclei
- Cardiac striated muscle that is only found in the heart - identifying feature are single nuclei and the presence of intercalated discs between the cells
- Smooth non-striated muscle that is controlled involuntarily by the autonomic nucleus per cell
What type of muscle has cylindrical cells and multiple peripheral nuclei?
Skeletal muscle
What is a sarcolemma?
A single cell forms a muscle fibre and its cell membrane is known as the sarcolemma
What type of muscle has singular nuclei and intercalated discs?
Cardiac
What are T tubules?
They are invaginations of the sarcolemma that conduct charge when the cell is depolarised
They are unique to muscle cells
What is the specialised endoplasmic reticulum that muscles have and what ion does it store?
Sarcoplasmic reticulum - large stores of calcium
Muscles have an intricate support structure of connective tissues…. describe it
- Each muscles fibre is surrounded by a thin layer of connective tissue known as endomysium
- These fibres are then grouped into bundles known as fascicles
- These are surrounded by a layer of connective tissue known as perimysium
- Many fascicles make up a muscle, which in turn is surrounded by a thick layer of connective tissue known as epimysium
What are the two contractile filaments in skeletal muscle?
Actin (thin filament) and Myosin (thick filament)
What is a sarcomere?
The function unit of contraction in a skeletal muscle fibre, it runs from Z line to Z line
Label this sarcomere and what the areas represent
Z line - where the actin filaments are anchored
M line - where the myosin filaments are anchored
I band - contains only actin
H zone - contains only myosin
A band - the lenght of a myosin filament, may include overlapping actin filaments
A useful acronym is MHAZI – the M line is inside the H zone which is inside the A band, whilst the Z line is inside the I band.
What two other regulatory proteins are associated with actin and what do they do?
- Troponin a small protein that binds the tropomyosin to the actin
- Tropomyosin a long protein that runs along the actin filament and blocks the myosin head binding sites
What are the three types of troponin and what do they do?
- Troponin I binds to the actin filament
- Troponin T binds to the tropomyosin
- Troponin C can bind to calcium ions
What are the stages of the excitation-contraction coupling on troponin/actin/myosin?
- Depolarising occurs at a neuromuscular junction, this is conducted down the t-tubules, causing a huge influx of calcium ions into the sarcoplasm from the sarcoplasmic reticulum
- Calcium binds to Trop C, which moves tropomyosin away from the myosin binding sites of actin
- Myosin head binds to actin, the power stroke pivots the myosin heads in a rowing motion, moving the actin towards the M line
- ATP then binds to the myosin head, causing uncoupling so it can happen again
What happens to the length of the sarcomere and its zones during the excitation-coupling?
- The length of the filaments do not change
- The sarcomere decreases in size
- The H zone and I band decrease in size
- The A band stays the same
- The Z lines come closer together
Where are tendons situated and what are the joining points called?
Tendons are between bone and muscle
The point at which the tendon joins the muscle is called the myotendinous junction
The point at which the tendon joins the bone is called the osteotendinous junction - it is attached by collagenous fibres called ‘Sharpey fibres’ that continue into the bone matrix
What is the origin, insertion and purpose of a tendon?
The origin is the proximal attachment of the tendon
The insertion is the distal attachment of the tendon
The purpose of a tendon is to transmit forces generated by the muscle to the bone to ellicit movement
What is a tendon mainly made of?
- Mainly type 1 collagen fibres - responsible for strength
- Proteoglycan - responsible for viscoelastic nature
What are the units of tendon composition?
- Primary collagen fibres, which consist of bunches of collagen fibrils, are the basic units of a tendon
- Primary fibres are bunches together to form subfasicles, groups of which bunch together to form secondary fasicles
- Fasicles bind together to form a tendon unit
- All the bundles are surrounded by a sheath of connective tissue called endotenon
- Endotenon in contiguous with epitenon, the fine layer of connective tissue that sheaths the tendon
What are tendon cells called and where do you find them?
- Tenoblasts - immature cells that give rise to tenocytes - occur in clusters, free from collagen fibres
- Tenocytes - mature cells found throughout the tendon structure, typically anchored to collagen fibres
What are the functions of bone?
- Haematopoiesis
- Lipid and mineral storage - bone is a reservior holding adipose tissue within the bone marrow and calcium within the hydroxyapatite crystals
- Support - bones form the framework and shape of the body
- Protection - especially the axial skeleton that surrounds the major organs of the body
What are the three types of cells in bone and their functions?
- Osteoblasts synthesise uncalcified/unmineralised extracellular matrix called osteoid
- Osteocytes as the osteoid mineralises, the osteoblasts become entombed between the lamellae in lacunae, where they become osteocytes, which monitor the minerals and proteins to regulate bone mass
- Osteoclasts are derived from monocytes and resorb bone by releasing H+ ions and lysosomal enzymes. They are large and multinucleated
What is the bone extracellular matrix and how is it organised?
It refers to the molecules that provide biochemical and structural support to cells
The matrix is organised into thin layers, known as lamellae
What is the main mineral salt in bones and what does it do?
Calcium hydroxyapatite associates with the collagen fibres, making bone hard and strong
Under the microscope, bone can be divided into two types.
What are these types and what are the differences between them?
- Woven bone (primary bone) - appears in embryonic development and fracture repair, as it can be laid down rapidly. It consists of osteoid (unmineralised ECM), with the collagen fibres arranged randomly. It is a temporary structure, soon replaces by lamellar bone
- Lamellar bone (secondary bone) - the bone of the adult skeleton. It consists of highly organised sheets of mineralised osteoid. This organised structure makes it much stronger than woven bone. Lamella bone itself can be divided into two types - compact and spongy
What are the periosteum and the endosteum?
- Periosteum is a layer of connective tissue, which covers the external surface of bone
- Endosteum lines the cavities within bone, such as the medullary canal, Volkmann’s canal and spongy bone spaces
What are the two types of lamellar bone and what are their properties?
- Cortical bone - which is compact, dense and rigid, containing Volkmann’s and Haversian canals
- Trabecular bone - spongy bone, marked by many interconnecting cavities, doesn’t contain Haversian and Volkmann’s canals
What is the structure of cortical bone?
- The lamellae are organised in concentric circles, which surround a vertical Haversian canal (transmits small neurovascular and lymphatic vessels). This entire structure is called an osteon.
- The Haversian canals are connected by horizontal Volkmann’s canals which anastomaose with the arteries of the Haversian canals.
- Osteocytes are located between the lamellae, within lacunae, which are interconnected by a series of tunnels called canaliculi
Where is bone marrow within the bone and what are the different types of bone marrow?
The spaces between trabeculae in trabecular bone is often filled with bone marrow
* Yellow bone marrow containes adipocytes
* Red bone marrow consists of haematopoietic stem cells
What are the two mechanisms of ossification (building new bone) and an example for each?
- Endochondral ossification - where hyaline cartilage is replaced by osteoblasts secreting osteoid - an example is femur
- Intramembranous ossification - where mesenchymal (embryonic) tissue is condensed to bone - an example is temporal bone and the scapula
How are the airways in children different from adults and what does this mean?
Narrower airways increase the risk of obstruction from:
* swelling (croup)
* foreign bodies (small toys or food)
* nasal mucous (from bronchiolitis
* large tongues
How is the oxygen consumption different in children and why?
Increased oxygen consumption due to higher respiratory rate driven by a higher metabolic rate
How does the increased respiratory rate in children affect water loss from the lungs?
It increases the water loss
How are children’s alveoli different and what is the effect of this?
Children have smaller and fewer alveoli, resulting in limited alveolar surface area for gas exchange and more dead space in the airway.
Infants must breathe faster to achieve adequate minute ventilation
How is fluid loss due to evaporation different in children?
Vulnerable to greater fluid loss through evaporation from their large body surface area. They require greater fluid requirements to maintain adequate circulating volume
How do children physiologically alter their cardiac output?
They increase their heart rate to increase their cardiac output due to their difficulty changing stroke volume. Their heart is large in relation to body size and has less contractile efficiency
How is temperature regulation susceptibility different in children?
Temperature regulation is not well developed. Exposure can result in hypothermia for neonates and infants. There are also susceptible to heat loss from the surface of their head when exposed.
When does the anterior and posterior fonatanelle remain open til?
Anterior - 12-18 months of age
Posterior - 2-3 months of age
How does having a higher metabolic rate effect children?
- Increased waste production
- Increased fluid and nutrition requirements
- More susceptible to rapid fluid loss
- Higher respiratory rate
- Increased oxygen consumption
- Higher cardiac output
- Higher oxygen delivery
- Increased workload for cardiovascular system
What is the expected urine output of a child?
1-2ml/kg/hr
What is the macro-organisation of skeletal vs smooth vs cardiac muscle?
Skeletal muscle
fascicles and motor unit
Smooth muscle
sheets and bands
Cardiac muscle
function syncytium
What is the innervation of skeletal vs smooth vs cardiac muscle?
Skeletal muscle
voluntary motor, every cell, no automaticity
Smooth muscle
autonomic, not every cell, automaticity
Cardiac muscle
autonomic, not every cell, limited automaticity
What is the metabolism of skeletal vs smooth vs cardiac muscle?
Skeletal muscle
High energy requirements, fatiguable, very fast conduction
Smooth muscle
Low energy requirements, non-fatiguable and slow conduction
Cardiac muscle
Extremely high energy requirements, non-fatiguable, fast conduction
What is the histology of skeletal vs smooth vs cardiac muscle?
Skeletal muscle
Huge and long, multinucleated cells arranged in sarcomeres with T-tubules
Smooth muscle
Very small single nucleus disorganised cells with cavolae
Cardiac muscle
Small binucleated cells arranged in sarcomeres with T-tubules
What are dense bodies in the smooth muscle and what do they do?
The contractile elements of the smooth muscle insert along the entire length of the myocyte, anchored to ‘dense bodies’.
They are rigid and rather large. They function as attachment points for intermediate filament cables made of desmin and contractile actin filaments
What is the central nervous system vs the peripheral nervous sytem?
Central nervous system is made up of the brain and the spinal cord
Peripheral nervous system is made up of cranial and spinal nerves, ganglia, plexuses, and sensory receptors
What is the autonomic nervous system?
It is the part of the nervous sytem that is responsible for homeostasis. Except for skeletal muscle, innervation to all other organs is from the ANS.
Classic definiton: preganglionic and postganglionic neurons within the sympathetic and parasympathetic divisions
What are the two divisons of the autonomic nervous system?
Sympathetic & Parasympathetic
Some target organs are innervated by both divisons and others are controlled by only one
What are the differences between preganglionic and post-ganglionic neurons?
The cell bodies of the preganglionic neurons are located in the intermediolateral (IML) column of the spinal cord and in motor nuclei in the cranial nerves.
The axons of the preganglionic neurons are small-diameter, myelinated, relatively slow conducting B fibers
The axons of the postganglionic neurons are mostly unmyelinated C fibers and terminate on the visceral effectors
How many postganglionic neurons does a preganglionic axon diverge to?
Usually around 8 or 9.
In this way, autonomic output is diffuse
How do alpha-motor neurons differ from preganglionic axons?
In contrast to the large diameter, rapidly conducting alpha-motor neurons, preganglionic axons are myelinated, relatively slow conducting B fibers
What neurotransmitter is released by all neurons whose axons exit the CNS and what neurons does this include?
Acetylcholine
It is released by cranial motor neurons, alpha-motor neurons, gamma-motor neurons, preganglionic sympathetic neurons, and preganglionic parasympathetic neurons
What neurotransmitters do postganglionic sympathetic and postganglionic parasympathetic neurons release?
Postganglionic parasympathetic neurons also release acetylcholine
Postganglionic sympathetic neurons release either norepinephrine or acetylcholine
Where are the sympathetic preganglionic neurons situated?
In contrast to alpha-motor neurons, which are located at all spinal levels - sympathetic preganglionic neurons are located in the IML of only the first thoracic to the third or fourth lumbar segments
What is the path of the sympathetic neurons?
- The preganglionic sympathetic neurons leave the spinal cord at the level of the vertebral body
- They exit via the ventral root the seperate from the ventral route via the white rami communicans, they project to the adjacent sympathetic paravertebral ganglion
- Some of them end here on the cell bodies of the postganglionic neurons
- Some of them pass through the sympathetic chain and end on postganglionic neurons located in prevertebral (or collateral) ganglions
- Some of them leave the chain ganglia and re-enter the spinal nerves via the grey rami communicans
What is the sympathetic chain?
Paravertebral ganglia are located adjacent to each thoracic and upper lumbar spinal segment, there are a few ganglia adjacent to the cervical and sacral spinal segments
They are all connected together via the axons of preganglionic sympathetic neurons that travel rostrally or caudally. Together these axons and ganglia for the sympathetic chain
Where are the preganglionic parasympathetic ganglions?
They are located in several cranial nerve nuclei (III, VII, IX, and X)
What makes up the cerebrum?
It includes the cerebral hemispheres and the basal ganglia.
The cerebral hemispheres are separated by the falx cerebri within the longitudinal cerebral fissure
Label this diagram with the sulci, prominent gyri and lobes
What is the diencephalon?
It consists of:
epithalamus
dorsal thalamus
hypothalamus
It forms the central core of the brain
Where is the midbrain? Which cranial nerves is it associated with?
The rostral part of the brain, it lies at the junction of the middle and posterior cranial fossa.
CN III and IV
Where is the pons? What cranial nerve is associated with it?
The part of the brainstem between the midbrain rostrally and the medulla oblongata caudally. It lies in the anterior fossa.
CN V is associated with it
Where is the medulla oblongata? What cranial nerves are associated with it?
It is the most caudal subdivision of the brainstem that is continuous with the spinal cord - it lies in the posterior cranial fossa.
CN IX, X, XI, XII
What does the ventricular system of the brain consist of?
It consists of two lateral ventricles, and the midline 3rd and 4th ventricles connected by the cerebral aqueduct. CSF fills the ventricles
Where does CSF travel out of the ventricles?
It is created in the ventricles.
It either drains into the subarachnoid space via the fourth ventricle through a single median aperture and paired lateral apertures.
or
CSF flows into the subarachnoid cisterns and from there travels through the sulci and fissures of the cerebral hemispheres
What happens if the median and lateral apertures get blocked?
The CSF gets trapped and you get hydrocephalus
What are subarachnoid cisterns?
At certain areas on the base of the brain, the arachnoid and the pia are widely separated by the subarachnoid cisterns, which contain CSF and soft tissue structures that anchor the brain
How much CSF is secreted daily and how does it happen?
400-500mls/day
Mainly secreted by the choroidal epithelial cells of the choroid plexus in the lateral, third and fourth ventricles
They are on invaginations in the roof of the third and fourth ventricles and the floor of the lateral ventricles
How is CSF absorbed?
The main site of CSF absorption is through the arachnoid granulations. It extends into the cores of the arachnoid granulations. It enters the venous system through two routes
1. mostly by transport through the cells of the arachnoid granulations into the dural venous sinuses
2. moves between the cells making up the arachnoid granulations
What is the function of the spinal cord?
It is the major reflex center and conduction pathway between the body and the brain
What structures protect the spinal cord?
The cyclindrical structure, slightly flattened anteriorly and posteriorly, is protected by the vertebrea, their associated ligaments and muscles, the spinal meninges and CSF.
Where does the spinal cord start and end?
It begins as a continuation of the medulla oblongata.
In adults it is 42-45cm long.
It extends from the foramen magnum to the levels of L1-L2
The spinal cord is enlarged in two regions in relationship to innervation of the limbs. Where are these?
- The cervical enlargement extends from C4 to T1 and most of the anterior rami of the nerves arising from it form the brachial plexus
- The lumbosacral enlargement extends from T11 to S1 - the anterior rami of the nerves arising from it form the lumbar and sacral plexuses
How many cervical nerve roots are there and what level do they exit the canal?
8
C1 passes superior to the arch of C1 vertebrae
C2-7 pass through foramina superior to their vertebrae
C8 passes through the foramina in between C7-T1 (note there is no C8 vertebrae, only the nerve!)
How many thoracic nerve roots are there and what level do they exit the canal?
12
They all pass through foramina inferior to their corresponding vertebrae
How many lumbar nerve roots are there and what level do they exit the canal?
5
They all pass through foramina inferior to their corresponding vertebrae
How many sacral nerve roots are there and what level do they exit the canal?
5
They branch into posterior and anterior rami in the sacrum, with the respective rami passing through the anterior and posterior sacral foramina
What is the filum terminale?
It arises from the tip of the conus medullaris and descends among the spinal roots, perforating the dura, continuing through the sacral hiatus as the filum terminale externum to attach to the dorscum of the coccyx to anchor the spinal cord
What does the spinal meninges consist of?
Internal to external:
Pia matter
Arachnoid matter
Dura matter
What is spinal dura matter made of?
Mainly tough fibrous tissue with some elastic fibres
What is the epidural space made of and how long is it?
The spinal dura is separated from the vertebral canal by the epidural space.
It is occupied by epidural fat.
It runs the length of the vertebral canal
How does the spinal dura merge with the brain dura?
The spinal dura forms the spinal dural sac, which adheres to the margin of the foramen magnum, where it is continuous with the cranial dura matter
How does the spinal dura merge with the epineurium (outer connective tissue protecting the spinal nerves)?
The spinal dural sac has tapering lateral extensions that surround each pair of posterior and anterior nerve roots as dural root sheaths, which blend with the epineurium
What is spinal arachnoid matter?
It is a delicate, avascular membrane composed of fibrous and elastic tissue that lines the spinal dural sac
What is the subarachnoid space and what does it consist of?
It is the space between the arachnoid and the pia matter.
It is filled with CSF and contains the spinal cord, spinal nerve roots and spinal ganglia
What is the dura-arachnoid interface?
The spinal arachnoid is not attached to the spinal dura but is held against it by the pressure of the CSF.
Their aposition is called the dura-arachnoid interface
How are the arachnoid matter and pia matter connected?
Delicate strands of connective tissue, the arachnoid trabeculae, they span the subarachnoid space connecting the spinal arachnoid and pia
What is the pia matter and what is it made of?
The spinal pia matter, the innermost covering membrane of the spin cord, is thin and transparent and closely follows all the surfaces of the spinal cord.
It covers the nerve roots and blood vessels and continues as the filum terminale.
What is the bilateral ligament that runs longitudinally on both sides of the spinal cord? What is it made of?
Where does it attach?
Denticulate ligament
It consists of a fibrous sheet of pia extending midway between the posterior and anterior nerve roots from the lateral surfaces
It attachs to the cranial dura immediately superior to the foramen magnum and extends from the conus medullaris
What is a neuron composed of?
A cell body with processes called dentrites and an axon, which carry impulses to and away from the cells, respectively
What are multipolar motor neurons? Where are they in the nervous system?
They have two or more dendrites and a single axon that may or may not have one or more collateral branches
All of the motor neurons that control skeletal muscle and comprise the autonomic nervous system are multipolar motor neurons
What are pseudounipolar sensory neurons? Where are they in the nervous system?
They have a short, apparently single (but actually double) process extending from the cell body, which separates into a peripheral process, conducting impulses from the receptor organ toward a cell body. The cell body is located outside the CNS in sensory glanglia, and are thus part of the PNS. They communicate with each other at neurotransmitter synapses.
What are neuroglia?
They are non-neuronal, non-excitable cells that form a major component of nervous tissue, supporting, insulating and nourishing the neurons.
In the CNS, what is a nucleus and where is it found?
A nucleus is a collection of cell bodies in the CNS.
They lie within and constitue the grey matter
In the CNS, what is a tract and where is it found?
A bundle of axons within the CNS connecting neighbouring or distal nuclei of the cerebral cortex is called a tract.
The interconnecting fibre tract matrix forms the white matter
What are the posterior and anterior horns?
In transverse sections of the spinal cord, the gray matter forms an H. The struts of the H are horns; hence there are right and left dorsal (posterior and ventral (anterior) horns
Nerves are fairly strong and resilient because the nerve fibres are supported and protected by three consecutive tissues coverings.
What are they?
- Endoneurium, delicate connective tissue immediately surrounding the neurilemma cells and axons
- Perineurium, a layer of dense connective tissue that encloses a fasicle of nerve fibres, providing an effective barrier against penetration by foreign bodies
- Epineurium, a thick connective tissue sheath that surrounds and encloses a bundle of fascicles, forming the outermost covering of the nerve, it includes blood vessels, lymphatics and fatty tissue
What are the two types of nerve in the peripheral nervous system?
- Afferent (sensory) fibres convey neural impulses to the CNS from the sense organs
- Efferent (motor) fibres convey neural messages from the CNS to effector organs
Spinal nerves initially arise from the spinal cord as rootlets, which converge to form two roots.
What are they and what nerves are in each root?
- Anterior (ventral) nerve root, consisting of motor (efferent) fibers passing from the nerve cell bodies in the anterior horn to effector organs
- Posterior (dorsal) nerve root, consisting of sensory (afferent) from cell bodies in the spinal or posterior root ganglion that extend peripherally to sensory endings and centrally to the posterior horn
The spinal posterior and anterior nerve roots combine and then what happens?
They form a mixed (both sensory and motor) spinal nerve, which divides into two rami : a posterior and an anterior rami, which both contain a mix or sensory and motor nerves
What is a dermatome and a myotome?
Dermatome - the unilateral area of skin innervated by the sensory fibres of a single nerve
Myotome - the unilateral muscle mass receiving innervation from the fibres conveyed by a single spinal nerve
What is the somatic nervous system? It’s broken into two systems, what are they?
It is composed of somatic parts of the CNS and PNS. It provides sensory and motor innervation to all parts of the body, expect the viscera, smooth muscle and glands
The somatic sensory system transmits senations of touch, pain, temperature and position from sensory receptors
The somatic motor system innervates only skeletal muscle, stimulating voluntary and reflexive movement by causing the muscle to contract
What does a nerve fiber consist of?
An axon, a neurolemma and surrounding endoneurial connective tissue.
Do large or small myelinated or unmyelinated fibres conduct faster?
Larger myelinated fibers conduct faster than smaller unmyelinated fibres
What types of nerves are myelinated?
A & B
What types of nerves are unmyelinated?
C
What do A alpha nerves transmit?
Somatic, motor and proprioception
What is the diameter of different types of A nerves?
Alpha - 16um
Beta - 8um
Gamma - 4um
Delta - 4um
What is the speed of the different A type nerves?
Alpha - 100m/s
Beta - 50m/s
Gamma - 25m/s
Delta - 25m/s
What do A beta nerves transmit?
Touch
What do A gamma nerves transmit?
Motor to muscle spindles
What do A delta nerves transmit?
Pain and temperature (fast pain or epicritic pain)
What do B nerves transmit?
Preganglionic autonomic
What is the diameter and speed of B nerves?
Diameter - 2um
Speed - 12.5m/s
What does a C type nerve transmit?
Pain and temperature (slow pain and protopathic pain)
Postganglionic sympathetic nerve
What is the diameter and speed of C nerves?
Diameter - 1um
Speed - 2m/s
What is the umbilicus dermatome?
T10
What dermatome supplies the nipple?
T4
What is the largest cranial nerve?
Trigeminal nerve
Where does the sensory root for the trigeminal root lie?
In the trigeminal (semilunar) ganglion that is at the apex of the petrous temporal bone
Where do the motor neurons of the trigeminal nerve begin?
The upper pons
Where do the cranial nerve nucleis lie?
First 4 cranial nerve nuclei lie above the pons
Second 4 lie in the pons
Last 4 lie below the pons
What is a myotome?
A unilateral muscle mass receiving intervention from fibres conveyed by a single spinal nerve (from the anterior ramus division)
What is a myotome?
A unilateral muscle mass receiving intervention from fibres conveyed by a single spinal nerve (from the anterior ramus division)
What myotomes do knee flexion?
L5, S1
What nerves do shoulder adduction and medial rotation?
C6, C7, C8
What myotome does great toe extension?
L5
What myotome does tibialis anterior and posterior and inversion of the foot?
L4
What myotome does extensor hallucis longus and extension of the great toe?
L5
What myotome does gastrocnemius, plantarflexion of the foot, ankle jerk?
S1
What myotome does small muscles of the foot?
S2