anat/physio/patho Flashcards
Name the 4 lobes of the brain
Frontal, parietal, temporal, occipital
List the subdivisions of the frontal lobe and their functions
- Primary motor cortex - execution of movements
- Secondary motor cortex - planning of complex movements
- Broca’s speech area - speech production
- Prefrontal cortex - higher order mental capabilities like behaviour and planning
- Frontal eye field - coordination of eyes to focus on a single object
What is the function of the parietal lobe?
Primary somatosensory cortex where all the information from the somatic sensory pathways are transmitted to and processed
Describe what is the sensory homunculus
A visual representation of how much processing power is allocated through all the body parts.
Face and hands are the most, ie. they can do the most precise fine motor functions and are the most sensitive.
What is the function of the temporal lobe?
- Primary auditory cortex = process hearing information coming from CN8
- *Wernicke’s speech area = speech understanding
What are the 2 areas of the brain responsible for speech and which lobes are they found in respectively?
Broca’s = speech PRODUCTION, found in frontal lobe
Wernicke’s = speech INTERPRETATION, found in temporal lobe
What is the function of the occipital lobe?
Primary and secondary visual cortex = VISION
What 2 functions does the cerebellum play an important role in?
Balance and coordination
List the anatomical divisions of the cerebellum
From medial to lateral,
1. Vermis **
2. Intermediate zone
3. Lateral hemispheres
List the functional divisions of the cerebellum
- Vestibule cerebellum - postural maintenance
- Spinocerebellum - Integrate sensory input with motor commands
- Cerebrocerebellum
Which part of the brainstem is the cardiopulmonary centre?
Medulla oblongata
Which part of the brainstem does the cranial nerves 5,6,7,8 branch from?
Pons
Which cranial nerves emerge from the pontomedullary junction?
Cranial nerves 5,6,7,8
Name the 4 branches of the ICA
- Ophthalmic artery
- Anterior cerebral artery
- Middle cerebral artery
- Posterior communicating artery
Where does the ophthalmic artery supply?
Orbit
Forehead via supratrochlear artery
Dorsum of nose via supraorbital artery
Which part of the brain does the ACA supply?
- Midline of frontal lobe
- Superior medial parietal lobe
Which part of the brain does the MCA supply?
- Lateral cerebral cortex
- Anterior temporal lobes
Which artery does the posterior communicating artery connect to?
Posterior cerebral artery
Describe which is the main artery supplying the intra and extra cranial structures
Intra-cranial: ICA and vertebral arteries
Extra-cranial: ECA
Which part of the brain does the PCA supply?
- Occipital lobe
- Temporal lobe
- Thalamus
- Choroid plexus of third and lateral ventricles
Which special sense will be affected if the PCA is occluded?
Vision
Because the PCA supplies the occipital lobe which houses the primary visual cortex
List the significance of the Circle of Willis
- Provides collateral blood flow between the anterior and posterior circulations of the brain to PROTECT AGAINST ISCHEMIA
- Common site for berry/saccular aneurysms which is the most common cause of non-traumatic SAH.
What is the main vessel supplying the extra-cranial structures?
External carotid artery
**List the branches of the ECA
- Superior thyroid artery
- Ascending pharyngeal artery
- Lingual artery
- Facial artery
- Occipital artery
- Posterior auricular artery
- Maxillary artery
- Superficial temporal artery
Which nerve is closely related to the superior thyroid artery?
External laryngeal nerve
Which nerve is closely related to the inferior thyroid artery?
Recurrent laryngeal nerve
How does the lingual artery enter the oral cavity?
From behind the hypoglosus muscle
What parts of the face does the facial artery supply?
Muscles of soft palate, sublingual and submandibular gland
Orbicularis oculi and oris
Superficial face
What muscles does the occipital artery supply?
THINK BACK OF NECK!
SCM & trapezius
What is the name of the artery that branches out from ECA within the parotid gland?
Posterior auricular artery
Name the 2 terminal branches of the ECA
Maxillary artery
Superficial temporal arteries
What is a key branch of the maxillary artery involved in SAH?
Middle meningeal artery
How does the middle meningeal artery enter the cranial cavity?
Via foramen spinosum
What is the main artery supplying the EAR?
Posterior auricular artery
What is the artery supplying the muscles of mastication?
Maxillary artery
What is a branch of the maxillary artery that goes to the mandible?
Inferior alveolar artery (passes through mandibular foramen)
Which part of the brain produces CSF?
Choroid plexus
List the functions of CSF
- **Protection for the brain (shock absorption)
- Buoyancy (allows the brain to maintain its density)
- Prevention of brain ischemia (decreasing the amt of CSF in limited space inside the skull decreases total ICP)
- **Removal by-products of metabolism
** Describe CSF circulation in the brain
Produced by choroid plexus
Lateral ventricles to 3rd ventricle via interventricular foramen
3rd to 4th ventricle via cerebral aqueduct
4th ventricles has openings for the CSF to flow into the subarachnoid space
Reabsorbed into dural venous sinuses through arachnoid granulations.
Choroid plexus -> lateral ventricle -> 3rd -> 4th ventricle via aqueduct -> subarachnoid -> arachnoid granulation -> DVS
What structure of the brain reabsorbs/recycles CSF?
Arachnoid granulations
Which is the most clinically important dural venous sinus and what structures pass through it?
Cavernous sinus
CN 3,4,6,V1,V2
Where is the highest number of arachnoid granulations found?
Superior sagittal and tranverse sinuses
Where does dural venous sinuses drain into?
Internal jugular vein
Describe the most common cause of epidural/extradural haemorrhage
Trauma associated with skull fracture, specifically fracture at the pterion
The fracture causes rupture of the MIDDLE MENINGEAL ARTERY
What will I see on a CT scan if there is epidural haemorrhage?
Biconvex (lens-shaped) hyperdense area
Describe the most common cause of subdural haemorrhage
Rupture of bridging veins, especially in elderly due to age related shrinking of the brain causing the distance between the brain and skull to increase.
What will I see on a CT scan if there is subdural haemorrhage?
Crescent-shaped haematoma
Describe the most common cause of subarachnoid haemorrhage
Rupture of berry aneurysm, most commonly at the Circle of Willis.
Or arteriovenous malformation
Or coagulopathies
What will I see on a CT scan if there is subarachnoid haemorrhage?
Blood fills the sulci and around the Circle of willis.
Blood may also pool in the basal cisterns, forming a “star-shaped” pattern.
Describe the most common cause of intraparenchymal haemorrhage
HYPERTENSION!!!
Cerebral amyloid angiopathy
Vascular abnormalities (eg. arteriovenous malformations)
Describe the sequence of events from the photoreceptor to the brain when processing images
- Photoreceptors recieve light and undergo phototransduction.
- Optic nerve exits orbit via optic canal
- Hemi decussation of nasal hemiretina tract at optic chiasm
- Optic tract (ipsilateral temporal and contralateral nasal)
- Synapses at the lateral geniculate nucleus (LGN) of the thalamus
- Optic radiation
- Primary visual cortex in occipital lobe
Which are the 4 nerves with parasympathetic component?
CN 3,7,9,10
What is the parasympathetic function of CN3?
Innervation of the smooth muscles of the eye (ie. sphincter pupillae and ciliary muscles).
Sphincter pupillae is for pupillary light reflex and ciliary muscle is to adjust the lens for accomodation.
What is the parasympathetic function of CN7?
Supply all the glands in the head EXCEPT parotid so lacrimal, sublingual, submandibular
What is the parasympathetic function of CN9?
Innervate the parotid gland and increase its secretions
What is the parasympathetic function of CN10?
Heart, lungs, GIT parasympathetic functions
What is the visual field defect associated with lesion to the optic nerve?
Ipsilateral monocular blindness
What is the visual field defect associated with lesion to the central optic chiasm?
Bitemporal hemianopia
Central optic chiams aka the point of decussation -> both the nasal visual fields affected -> lost of peripheral vision on both sides
In what condition is a lesion to the central optic chiasm seen more often?
Pituitary tumour
What is the visual field defect associated with lesion to the lateral optic chiasm?
Ipsilateral nasal hemianopia
Depending on which side is affected, it affects the ipsilateral temporal vision -> loss of central vision.
Right lateral optic chiasm -> right temporal visual field disrupted -> right central vision gone
What is the visual field defect associated with lesion to the optic tract?
Contralateral homonymous hemianopia.
Right: right temporal (right central) and left nasal (left periphery)
- Right central and Left peripheral vision loss
Left: left temporal (left central) and right nasal (right periphery)
- Left central and Right peripheral vision loss
What is the visual field defect associated with lesion to the optic radiation?
Contralateral quadrantanopia
What is the visual field defect associated with lesion to the Meyer’s loop?
Contralateral quadrantanopia
What is the visual field defect associated with lesion to the visual cortex?
Contralateral homonymous hemianopia with macular sparing
Because even if there is an occlusion -> stroke -> infarct of visual cortex, the visual cortex will still have blood supply from collateral vessels, it will not totally die off.
Hence not complete blindness and got macular sparring.
Where does CN 1 emerge from in the skull? State the cranial fossa component as well
Cribriform plate, anterior CF
Where does CN 2 emerge from in the skull? State the cranial fossa component as well
Optic canal, middle CF
Along with ophthalmic artery which is a branch of ICA
Where does CN 3 emerge from in the skull? State the cranial fossa component as well
Midbrain
Middle CF, supra-orbital fossa