Anaphy Flashcards
Nervous System
Brain and spinal cord
Central Nervous System
Nerves and Ganglia
Peripheral nervous System
Functional classification of the nervous system include what
Sensory division and Motor division
The motor division is divided into the
Somatic nervous system or autonomic nervous system
This contains the fight-or-flight and parasympathetic rest-and-digest
Autonomic division
Support and protect neurons in the CNS
Neuroglia
In the CNS there are phagocytes
Microglia
In the CNS Myelinate neuron processes
Oligodendrocytes
In the CNS Line fluid-filled cavities
Ependymal cells
In the CNS these brace neurons and filter nutrients
Astrocytes
In the PNS these are myelinate neuron processes
Schwann cells
In the PNS these protects neuron cell bodies
Satellite cells
Type of processes fibers that carry electrical impulses toward the cell body
Dendrites
Type of processes fibers that generate and conduct impulses away from the cell body
Axons
Axons often release ______ at the axon terminals
Nuerotransmitter
Speeds nerve impulse transmission
Myelin
Clusters of neuron cell bodies in the CNS are
Nuclei
Clusters of neuron cell bodies in the PNS are
Ganglia
Bundles of nerve fibers in the CNS are
tracts
Bundles of nerve fibers in the PNS are
nerves
Functional classification are based on direction of _____
impulse transmission
Sensory neurons are
afferent neurons
Motor neurons are
efferent neurons
Interneurons are
Association neurons
Dendritic ending of sensory neurons are bare or are associated with
Sensory receptors
Structural classifications
Unipolar neurons, bipolar neurons, and multipolar neurons
The membrane of a neuron at rest is
Polarized (outer face if more positive compared to its inner face)
When Sodium ions enter the cell
Depolarization
Once begun, the _____ is all-or-nothing, and it continues over the entire surface of the axon
Action potential
Electrical conditions of the resting state are restored by the diffusion of potassium ions out of the cell
Repolarization
Ionic conditions of the resting state are restored by the
sodium-potassium pump
A neuron communicates with its target by releasing
neurotransmitters
Neurotransmitters diffuse across the ____, attach to membrane receptors on the postsynaptic cell
Synaptic cleft
A rapid, predictable response to a stimulus
Reflex
Two types of reflex
Somatic reflexes and autonomic reflexes
Has at least five components: receptor, sensory neurons, CNS integration center, motor neurons, and effector
Reflex arc
The largest part of the brain, composed of superficial gray matter and deep white matter
Cerebral hemispheres
The cerebral cortex surface includes
- gyri
- sulci
- fissures
Regions of gray matter deep within the white matter that modify voluntary motor activity
Basal nuclei
Disorders of the basal nuclei
Parkinson’s disease and Huntington’s disease
Superior to the brain stem, enclosed by the cerebral hemispheres
Diencephalon
Relay station for sensory impulses passing to the sensory cortex for interpretation
Thalamus
Most important regulatory center of the autonomic nervous system
Hypothalamus
Includes the Pineal gland and the choroid plexus of the third ventricle
Epithalamus
Short region inferior to the hypothalamus that merges with the spinal cord
Brain Stem
Primarily fiber inferior to the hypothalamus that merges with the spinal cord
Midbrain
Inferior to the midbrain, has fiber tracts and nuclei involved in respiration
Pons
Most inferior part of the brain stem, contains fiber tracts and autonomic nuclei involved in the regulation of vital life activities
Medulla oblongata
Extends length of brain stem, involved in motor control of visceral organs and consciousness and the sleep/wake cycle
Reticular formation
Coordinates muscle activity and body balance
Cerebellum
Three connective tissue membranes protecting the CNS
Meninges
Though, outermost connective tissue membrane protecting the CNS
Dura matter
Middle, weblike connective tissue membrane protecting the CNS
Arachnoid mater
Innermost, delicate connective tissue membrane protecting the CNS
Pia mater
Provides a watery cushion to the CNS
Cerebrospinal fluid
The cerebrospinal fluid is formed by the ____ found in the _____, _______, _______
Choroid plexuses, subarachnoid space, ventricles, and central canal
CSF is continually formed and drained into dural venous sinuses via
Arachnoid granulations
Is composed of relatively impermeable capillaries
Blood-brain barrier
concussions are ___ and contusions are ______
reversible damage, irreversible damage
Trauma-induced brain injuries may be aggravated by ______ or _______
Intracranial hemorrhage or cerebral edema
Or also known as strokes and is the blockage of blood circulation to brain neurons, resulting in death of brain tissue
Cerebrovascular accidents (CVAs)
Temporary restriction of blood flow to the brain
Transient ischemic attack (TIA)
A reflex center and conduction pathway, extends from the foramen magnum to L1 to L2
Spinal Cord
Combine to form spinal nerves
Dorsal roots and Ventral roots
Is a bundle of neuron processes wrapped in connective tissue coverings
Nerve
12 pairs of nerves that extend from the brain to serve the head and neck region
Cranial nerve
21
Serve the posterior body trunk
Dorsal rami
Form plexuses that serve the limbs
Ventral rami
Part of the PNS, composed of neurons that regulate the activity of smooth and cardiac muscles and glands
Autonomic nervous system
The housekeeping or rest and digest system
Parasympathetic division
Second motor neurons are in the ______ close to the organ served
Terminal ganglia
The fight or flight subdivision and prepares the body to cope with some threat
Sympathetic division
_____ are in grey matter of the cord, ganglionic sympathetic neurons are in the _____ or in the ______
Preganglionic neurons, sympathetic trunk, collateral ganglia
Secrete norepinephrine
Postganglionic axon
Severe congenital brain disease include
cerebral palsy, anencephaly, hydrocephalus, and spina bifida
Lymphatic system
Consists of the lymphatic vessels, lymph nodes, and certain other lymphoid organs in the body
Lymphatic system
Extremely porous ____ pick up excess interstitial fluid
Lymph Capillaries
Also called lymphatics, have minivalves to ensure one-way flow towards the heart
Lymphatic vessels
Fluid flow in lymphatic vessels steps
- Fluid (lymph)
- larger lymphatics (lymphatic collecting vessels)
- Right lymphatic duct and Left Thoracic duct
Lymphatic structures clustered along lymphatic vessels that lymph flows through
Lymph nodes
Lymph nodes serves as multiplication sites for
Lymphocytes
The cortex contains ___ of lymphocytes, and the medulla is full of _____
Follicles, macrophages
The lymphoid organs include
Tonsils, Thymus, Peyer’s patches, Spleen
Remove bacteria trying to enter the digestive or respiratory tracts
Tonsils
Programming region for T lymphocytes
Thymus
Prevent intestinal bacteria from penetrating more deeply into the body
Peyer’s patches
Red blood cell graveyard and blood reservoir
Spleen
Functional system composed of the innate defense system and the adaptive defense system
Immune System
Includes nonspecific and chemical protections against
Pathogens
Lymphocytes that act nonspecifically to lyse virus-infected, malignant cells ad other nonspecific targets
Natural killer cells
Prevents spread of harmful agents
Inflammatory response
Protective leukocytes enter area by ____, fibrin walls off the area, and tissue repair occurs
Diapedesis
Engulf and destroy pathogens, process is enhanced when the pathogen surface is altered by attachment of antibodies and or complement
Phagocytes
Becomes fixed on the membrane of a foreign cell to cause lysis
Complement
A group of proteins synthesized by virus-infected cells to prevent viruses from multiplying in other body cells
Interferons
Enhances the fight against infectious microorganisms by increasing metabolism and by causing the liver and spleen to store iron and zinc
Fever
The third line of defense is
antigen specific
Branch of adaptive body defense that is mediated by antibodies
Humoral immunity
Branch of body defenses are mediated by T lymphocytes
Cellular immunity
Large, complex molecules recognized as foreign by the body
Antigens
Complete antigens provoke an ____ and bind with products of that response
immune response
Small molecules that are unable to cause an immune response by themselves, when they bind to body proteins, the complex is recognized as foreign
Incomplete antigens (haptens)
Are involved in adaptive defense
Lymphocytes and antigen-presenting cells
Develop immunocompetence in the thymus and oversee cell-mediated immunity
T cells
Develop immunocompetence in bone marrow and provide humoral immunity
B cells
____ of B cells occurs when antigens bind to their receptors, causing them to proliferate
Clonal Selection
Clone members become plasma cells which secrete antibodies which are called the
primary humoral response
Other clone members become ____ capable of mounting a rapid attack against the same antigen in subsequent meetings
Memory cells
Memory cells provide
Immunological memory
Is produced by a person’s own body during an infection or via vaccine and provides memory
Active immunity
Is conferred when antibodies produced by another person are injected into the bloodstream or when the mother’s antibodies cross the placenta, no immunological memory occurs
Passive immunity
Proteins produced by sensitized B cells or plasma cells in response to an antigen, they are capable of binding specifically with that antigen
Antibodies
An antibody is composed of ___ polypeptide chains
four
Each polypeptide chain has a ____ and _____
Variable region and constant region
Variable regions form ____ one on each arm of the Y
Antigen-binding sites
Five classes of antibodies, also called ____ exist
Immunoglobulins (IgM, IgA, IgD, IgG, IgE)
Antibody functions
1, Agglutination
2. Complement fixation
3. Neutralization
4. Opsonization
5. Precipitation
Are pure preparations of antibodies specific for a single antigen useful in diagnosing various infectious disorders and cancer and in treating certain cancers
Monoclonal antibodies
Sensitized by binding simultaneously to an antigen and a self-protein displayed on the surface of an APC
T cells
Specialize in killing foreign or infected cells directly
Cytotoxic T cells
Direct the adaptive immune response and interact to turn on both B and T cells
Helper T cells
Turn off immune response once foreign material is inactivated or destroyed
Regulatory T cells