analgesics Flashcards
1
Q
Wht is Reye’s syndrom
A
children tke aspirin to reduce viral infection
GI Disturbnce
Liver degenertion
encephlopthy
2
Q
Wht is mortlity rte for children taking aspirin?
A
35%
3
Q
Relationship between Cox 2 nd GI Toxicity?
A
inversly related
4
Q
Wht is most prescribed topic NSID?
A
acular
5
Q
What are ASA adverse effects?
A
headache; nausea; abdominal cramps, bleeding, hemorhagic diathesis, tinnitus, nephrotoxicity, respiratory alklosis, metabolic acidosis; acute poisoning by rep, non immune low doses hy[persen
6
Q
What is ASA overdosing?
A
10-30g
profound acid- base disturbances
fever
dehydaration
7
Q
what does therapy of ASA overdosing require?
A
dialysis
8
Q
What are contraindications of NSAiD?
A
active peptic ulcer chronic GIT inflammation heavy alcohol use HTN Diabetes Pregnancy 3rd trimeste conrreal denvervation and dry eye
9
Q
What are NSAID preparations ?
A
topical
oral
local injection
intravenous
