Anaesthetics and critical care Flashcards

1
Q

What is the criteria for ASA I?

A

Healthy, non-smoking, no or minimal alcohol use

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2
Q

What is the criteria for ASA II?

A

A patient with mild systemic disease without substantive functional limitations

  • Current smoker
  • Social alcohol drinker
  • Pregnancy
  • Obesity (BMI 30 - 40)
  • Well-controlled DM or HTN
  • Mild lung disease
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3
Q

What is the criteria for ASA II?

A

A patient with severe systemic disease with Substantive functional limitations

Poorly controlled Diabetes Mellitus/Hypertension, COPD, morbid obesity (BMI > 40), active hepatitis, alcohol dependence or abuse, implanted pacemaker, moderate reduction of ejection fraction, End-Stage Renal Disease (ESRD) undergoing regularly scheduled dialysis, history (>3 months) of Myocardial infarction, Cerebrovascular accidents

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4
Q

What is the criteria for ASA IV?

A

A patient with severe systemic disease that is a constant threat to life

Recent (< 3 months) of Myocardial infarction, Cerebrovascular accidents, ongoing cardiac ischaemia or severe valve dysfunction, severe reduction of ejection fraction, sepsis, DIC, ARD or ESRD not undergoing regularly scheduled dialysis

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5
Q

What is the criteria for ASA V?

A

A moribund patient who is not expected to survive without the operation

Ruptured abdominal/thoracic aneurysm, massive trauma, intra-cranial bleed with mass effect, ischaemic bowel in the face of significant cardiac pathology or multiple organ/system dysfunction

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6
Q

A 23-year-old male comes in after crashing his motorbike into a bus stop. pain and tenderness in the right leg, significant abdominal bruising, and tenderness diffusely over the ribcage.

HR 105, BP 105/62, RR 20, Sp02 98%

What is the most preferable as an induction agent for anaesthesia?

A

Ketamine doesn’t cause a drop in blood pressure so useful in trauma

It blocks NMDA receptors

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7
Q

What is the surgical prep required for oral fluids?

A

Patients having surgery may drink clear fluids until 2hrs before their operation

Drinking clear fluids before the surgery can help reduce headaches, nausea and vomiting afterwards

Clear fluids are water, fruit juice without pulp, coffee or tea without ilk and ice lollies

Patients are advised to fast from non-clear food atleast 6hrs before surgery

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8
Q

What is the management of DM treatment during and before surgery?

A
  • Patients treated with insulin who have good glycaemic control (HbA1c < 69 mmol/mol) and are undergoing minor procedures, can be managed during the operative period by adjustment of their usual insulin regimen - Reduce dose by 20%
  • Surgery requiring a long fasting period of more than one missed meal - or whose diabetes is poorly controlled - require variable rate intravenous insulin infusion (VRIII)
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9
Q

What is the main side effect of Etomidate? Also what is the main advantage of using it

A

Potentiates GABA

Primary adrenal suppression - secondary to reversibly inhibiting 11B-hydroxylase

  • Causes less hypotension than propofol and thiopental during induction and is therefore often used in cases of haemodynamic instability
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10
Q

What is the action of thiopental?main side effect and main reason for its usefulness?

A

A type of barbiturate (potentiates GABAA)

  • laryngospams
  • Highly lipid-soluble so quickly affects the brain
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11
Q

What can cause paralytic ileus after abdominal surgery?

A

Paralytic ileus can also occur in association with chest infections, myocardial infarction, stroke and acute kidney injury.

Deranged electrolytes can contribute to the development of paralytic ileus, so it is important to check potassium, magnesium and phosphate. As the bowel is not functioning as normal it is better to replace electrolytes intravenously.

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12
Q

when should clopidogrel be stopped before surgery?

A

Continue taking it unless bleeding risk is very high

7 days before surgery

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13
Q

when is warfarin stopped before surgery?

A

5 days before surgery and pateints are started on LMWH

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14
Q

when are ACEi stopped before surgery?

A

ACEi should be stopped on the day of the surgery

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15
Q

when is COCP stopped before surgery and when is it restarted?

A

stopped 4-6 weeks before surgery and re-started at least 2 weeks after the surgery

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16
Q

what is the first line drug used for nausea in pateints post-op GI?

A
  1. Ondansetron - first line - risk of QT prolongation and constipation
  2. Cyclizine - avoid in HF
  3. Dopamine - prochlorperazine - risk of extrapyramidal side effects
17
Q

what are the signs of local anaesthetic toxicity?

A
  1. numbness or tingling around the mouth
  2. tinnitus
  3. tremores
  4. dizziness
  5. paraesthesia

sinus bradycardia

18
Q

what is the tx for local anaesthetic toxicity?

A

stop administration of the local
ABCDE + ECG

Lipid emulsion 1ml/kg every 3 mins

19
Q

when is DVT prophylaxis started in pateints going for surgery?

A

at 6pm post Op

may need to continue medical prophylaxis for over a month at home

20
Q

what are the different ASA grades?

A
  1. Normally healthy
  2. Mild systemic disease
  3. Severe systemic disease that limits activity
  4. Systemic disease which is a constant threat to life
  5. Moribund: not expected to survive 24h even after op
21
Q

what are the factors that influence ease of intubation?

A

neck arthrtitis
dentures
loose teeth

22
Q

how are insulin dependent DMs managed before and after surgery?

A

stop the short acting insulin
Start sliding scale

Post -op - continue sliding scale until tolerating food

23
Q

how is steroid titrated in pts going in for surgery?

A

Need to increase steorids to cope with stress

major surgery - hydrocortisone IV high dose for 3 days
Minor surgery - hydrocortisone IV for 24hrs

24
Q

how do you manage anticoaguated pts going for surgery?

A

Very minor surgery may be undertaken w/o stopping warfarin if INR <3.5. Avoid epidural, spinal and regional blocks if anticoagulated

Low thromboembolic risk: e.g. AF. Stop warfarin 5d pre-op: need INR <1.5 –> Restart next day

High thromboembolic risk: valves, recurrent VTE - need bridging with LMWH - stop LMWH 12-18h before op. Restart warfarin th enext day

25
Q

what are the side effects of suxamethonium?

A
  1. Malignant hyperthermia

2. Hyperkalaemia (normally transient)

26
Q

what is the contraindication for using suxamethonium?

A

patients with penetrating eye injuries or acute narrow angle glaucoma, as suxamethonium increases intra-ocular pressure

27
Q

what are the side effects of atracurium?

A

hypotension

28
Q

what are the reversal agents for neuromuscular relaxants used?

A

suxamethonium - suggamadex

atracurium - neostigmine

29
Q

what is the diff in the mode of action of suxamethonium and atracurium?

A

non-depolarising agents - competitive antagonist of nicotinic acetylcholine receptors

depolarising agents - bind to the nictonic acetylcholine receptors - persistent depolarization of the motor end plate