Anaesthetics Flashcards
Types of anaesthesia
General anaesthesia- total loss of sensation
Regional anaesthesia- loss of sensation to a region or part of the body
Local anaesthesia- Topical, infiltration
Components of general anaesthesia
Amnesia- unconsciousness
Analgesia
Akinesis- immobilisation
What happens during GA
Monitoring
IV access
Start the process- induction of anaesthesia, analgesia and muscle relaxation
Maintenance
Monitoring in GA
ECG
SP02
NIPB
Airway gases- oxygen, CO2 and vapour
Airway pressure
Nerve stimulator- if a muscle relaxant is used
Temperature monitoring- temp should be 37 before surgery
Next step after monitoring
IV access
Attached to fluids
Start the process of GA
Drugs- amnesia- induction agents
Induction agents
Propofol
Thiopentone
Ketamine
Etomidate
Propofol
Most commonly used Dose- 1.5-2.5 mg/kg Lipid based Excellent suppression of airway reflexes Decreases incidence of PONV- post-op nausea and vomiting
Unwanted effects of propofol
Marked drop in HR and BP
Pain on injection
Involuntary movements
Thiopentone
Barbiturate
Dose- 4-5 mg/kg
Faster than propofol
Used mainly for rapid sequence induction- (when induction is required quickly to prevent aspiration)
Antiepileptic properties and cerebral protective
Unwanted effects of thiopentone
Fall in bp but rise in hr
Rash/bronchospasm
Intra-arterial injection- thrombosis and gangrene
contraindicated in porphyria
Ketamine
Dissociative anaesthesia- anterograde amnesia and profound analgesia
Used for sole anaesthetic for short procedures- pulling of wires, burn dressing change
Dose- 1-1.5 mg/kg
Slow onset (90 secs)
Rise in HR/BP, bronchodilation
In a patient with heart failure
Unwanted side effects of ketamine
Nausea and vomiting
Emergence phenomenon
Etomidate
rapid onset
Dose- 0.3 mg/kg
haemodynamic stability
lowest incidence of hypersensitivity reaction
Unwanted side effects
Pain on injection
Spontaneous movements
Adreno-cortical suppression
High incidence PONV