Anaesthesiology pastq Surgery 1 Flashcards
Anaesthesia: breed dispositions?
- Greyhound
- Dobermann
- Staffie/greyhound/haflinger
- NO thiopental (no fatty tissue for redistribution), recumbency.
- DCMP, blood clotting disorder
- sensitive to alpha 2 agonists
Anaesthesia: breed dispositions?
- Boxer
- Brachycephalic breeds
- Large breeds and individuals:
- Warmblood type and individuals
- No phenothiazine. Causes hypotension
- pre-oxygenation, short induction, fast intubation, late extubation
- Sensitive to hypoxia
- decreased effect of sedatives, higher metabolic rate
Positive effects of premedication?
- Decreased pain, stress, fear, accident risk
- Decreased anaesthetic dosage, side effects, material expenditure and costs
- Elimination of excitation stage, balanced anaesthesia
What is true according to induction?
IV access (vein cannulation) – reasons; drug admin, fluid therapy, emergencies Small animals: v. cephalica + saphena (v. jugularis). Induction using injectable (or inhalants): anaesthetics with moderate (or NO) side effects, rapid onset, short duration or counter-actable. The patient reaches an unconscious, indubitable status. Endotracheal tube introduction.
Elderly patients
Lengthened circulation time (delayed anaesthetic effect), decrease water content of cells, increased
fat content and lower compensation capacity
Stages of narcosis:
- Analgesia = induction phase
- Exitationis = excitatory phase
- Tolerantiae = surgical narcosis (divided into: superficial, surgical tolerance and deep)
- Asphyxiae = overdose, asphyxia (suffocation)
Antagonists:
- Opioids
- Alfa2
- Benzo
- Opioids/morph – Naloxone (also Naltrexone)
- Alpha2 – Atipamezole (also Yohimbine)
- Benzodiazepine – Flumazenil
What is the definition of recovery?
Ending anaesthetic administration (elimination)
Extubation (after the return of swallowing and coughing reflexes)
Capnograph:
Capnograph = graphic display of values on time chart. CO2 determination in air exhaled. Supervise
respiratory frequency, etCO2 and inhalant anaesthetic conconcentration, circuit pressure and tidal
minute volume (et = end tidal).
1. End tidal CO2 level correlates with arterial CO2 press (paCO2): paCO2 > etCO2.
2. Small animals: 5mmHg difference.
3. Horse: 5-20 mmHg difference.
4. Can be measured from sideflow or mainflow
Mixing circuit vaporizer:
Most inhalational anaesthetics are liquid (volatile): converted to gas state in vaporizer, can be
precisely admin
Vaporizing: temperature dependent (stronger at higher temp), requires energy (takes in heat from
environment), different anaesthetics – different gas pressure (requires purpose-built vaporizers)
Mixing system vaporizer:
Anaesthetic administration of modern vaporizers is not influenced by: flow rate, surrounding
environmental temperature, air pressure, temperature fluctuations during vaporizing, press
fluctuations during respiration or ventilation
Vaporizers can be classed as two main types: Injectable or variable-bypass.
Pain:
Complex, multidimensional negative experience (subjective). No linear correlation btw degree of
pathological changes and intensity of pain. Pain sensation strengthened by fear and stress. Parallel
nociceptive effects add up (superposition)
Characteristics of pain:
- Physiological (to prevent injury), pathological (due to actual injury)
- Origin: organic (somatic, visceral, neuropathic), psychogenic
- Intensity (strength)
- Duration of sensation: acute or chronic
- Localization (unusually sensitive: tooth pulp, cornea, serous membrane, head, thorax,
perineum, periosteum) - Modality (quality): mechanical, heat, chemical
Pathological pain:
- Hyperalgesia: small pain provocation, result in large pain sensation
- Allodynia: no pain provocation, but pain sensation occurs
Values: pulse-oxymetry and capnometry:
Ideal SpO2 value = 100%.
Normal: 100-97% (measure 02 saturation % of Hb). <90% = hypoxia
CO2 determination in air exhaled from endotracheal tube or nose.
Normal: etCO2 = 35-45 mmHg. Concentration: V%
Anaesthesia, foals?
Sedation/premedication: Benzodiazepine (diazepam, midazolam) in neonates
Alpha-2 agonist (Xylazine, Detomidine, Medetomidine, Romifidine)
Induction:
Light: inhalations or IV (Ketamine + Diazepam)
Deep: Ketamine + Diazepam + alpha-2 agonist, or Propofol.
Maintenance:
Inhalation
PIVA: Isoflurane + Ketamine + Lidocaine
TIVA (total IV anesthetics)
Can cattle and horse get the same drugs?
yes
Premedication:
- Acepromazine + Butorphanol
- Medetomidine + Butorphanol
- Medetomidine + Ketamine + Butorphanol
- Midazolam + Butorphanol
- Diazepam + Butorphanol
- Fentanyl
Induction:
Propofol IV, Ketamine + Diazepam IV
Ultra-short barbiturates, steroids (and inhalational) are also useful for induction
Inhalational: Isoflurane, Sevoflurane
Total IV: Propofol + Fentanyl
What is the most dangerous with anaesthesia on horse?
That the horse is recumbent on back for so long, the danger in laying down and waking/getting up
ASA (American society of Anaesthesiologists) – risk categories?
ASA 1: Healthy, symptom free. And/or: 6 weeks – 5 years
ASA 2: Mild systemic disease, no functional disorder apparent. And/or: 6 weeks – 5-8 years
ASA 3: Severe systemic disease with visible functional impairment, but not life threatening. And/or: 8-
10 years
ASA 4: Severe systemic disease, constant threat to patients life. And/or: 0-3 days, over 10 years
ASA 5: Moribund status, patient likely to die within 24 hours, with or without surgery
E (emergency): No time for classification (CEPOD 1).
Induction drugs?
NMDA (N-methyl D-aspartate) agonist, phenyl thiazine Ketamine + Midazolam Tiletamine + Solezopan Guaiphenesin (gge) Propofol
Pre-operative antibiotics procedures?
Indicated in orthopaedic surgery
30 min prior to surgery, single dose to reach sufficient tissue levels, second dose lasting for 3 hours