Anaemia of Chronic Disease (Secondary Anaemia)

Question 1

What 3 mechanisms contribute to anaemia in chronic disease?

Answer 1

(1) Poor use of iron in erythropoiesis
(2) Cytokine-induced shortening of RBC survival
(3) Reduced production of and response to erythropoietin

Question 2

Main Rx apart from treating underlying disease?

Answer 2

IV iron