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1. Beta lactámicos > AMOXICILINA > Flashcards

AMOXICILINA Flashcards

1
Q

Mecanismo de acción

A

Inhibe la acción de peptidasas y carboxipeptidasas impidiendo la síntesis de la pared celular bacteriana.

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2
Q

Indicaciones clínicas

A

Bacterias grampositivas y anaeróbicas y algunas gramnegativas (H. influenzae, Moraxella catarrhalis, E. coli, Proteus miriabilis) en neumonía comunitaria, otitis con otalgia leve.

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3
Q

Administración

A

Oral

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4
Q

Farmacocinética relevante

A

Estable en estado ácido.
La comida no interfiere con la absorción.
UPP: 20%.
Excreción: Renal 60%.
Vida ½ eliminación: 61 min. liberación inmediata. 1.5 h liberación prolongada.

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5
Q

Reacciones adversas

A

Hipersensibilidad (anafilaxis, diarrea, sindrome de Stevens-Johnson, necrosis epidérmica), diarrea por C. difficile, nausea.

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6
Q

Interacciones relevantes

A

Probenecid retrasa su absorción.

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7
Q

Precauciones y contraindicaciones relevantes

A

Categoria en el embarazo: B.

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1. Beta lactámicos (7 decks)

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