Amoebiasis Flashcards

0
Q

Entamoeba histolytica is found

A

Found world wide

Humans and non human mammals as reservoirs and definitive hosts

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1
Q

Cause

A

Entamoeba histolytica

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2
Q

Life cycle: Humans acquire cysts by

A

Oral-fecal route

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3
Q

Amoebiasis is transmitted during

A

The period of cyst passing and can continue for years after symptoms subside

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4
Q

Following ingestion of cysts …

A

Amoebas develop and invade the mucosa of the LARGE INTESTINES

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5
Q

Amoebas develop onto……… And pass out with ……….

A

Cysts, feces

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6
Q

Incubation period is

A

Weeks to months

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7
Q

Pathogenesis of the dz

A

Produce a toxin that erodes the mucosal surface of the LARGE INTESTINES resulting in ulcerative FLASK-SHAPED lesions

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8
Q

As a result of amoebiasis, amoebomas ( granulomas) can occur in the

A

Brain, spleen, liver, lungs, skin

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9
Q

Does partial or protective immunity follow amoebiasis?

A

NO

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10
Q

Amoebiasis symptoms:

Gastrointestinal

A
Fever
Bloody diarrhea
Leukocytosis
Anemia
Nausea
Vomiting and abdominal pain
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11
Q

Amoebiasis symptoms:

Respiratory

A

Chest pain and cough

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12
Q

Amoebiasis symptoms:

Hepatitis

A

Chills
Fever
Enlarged liver

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13
Q

Amoebiasis symptoms:

Brain abscesses

A

Can be fatal

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14
Q

Amoebiasis symptoms:

Conjunctivitis or skin sores

A

With a fetid odor

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15
Q

Diagnosis

A

Amoebas in exudate or feces containing a central karyosome or CYSTS contains 1-4 nuclei in IODINE stained preparation.

16
Q

Non-symptomatic positives must be differentiated from

A

Entamoeba dispar using
enzyme immunoassay or
indirect hemagglutination assays

17
Q

Treatment

A

Metronidazole: Amoebic stages

Diloxanide Furoate: cyst stages

18
Q

Should asymptomatic be treated?

A

YES