Acanthamoebic Keratitis

Question 0

Acanthamoeba castellani is found

Answer 0

Worldwide and is ubiquitous in Air, soil, and water and is an accidental human infection

Question 1

Cause of acanthamoebic keratitis

Answer 1

Acanthamoeba castellani

A non-arthropod borne amoeba

Question 2

In freshwater, Acanthamoeba Castellani multiplies as………..
Forming……………
That persists and revert back to……,,,,,,,
That live in micro environments in the soil

Answer 2

Amebas
Cysts
Amoebas

Question 3

The amoebic and cystic forms enter………. in the eyes, Lungs, skin or uterus of humans following exposure to………..

Answer 3

Damaged tissue

Soil, swimming, hot tubs, sewage systems, cooling towers or CONTACT LENS SOLUTION

Question 4

What age is Acanthamoeba Castellani disease found commonly?

Answer 4

30-50

Question 5

Incubation period for Acanthamoeba Castellani is

Answer 5

5-15 days

Question 6

This, on the eyelids and conjunctiva play a role in the establishment of disease

Answer 6

What is commensal bacterial co-infection?

Question 7

What do the amoebas release?

Answer 7

Collagenase and proteolytic enzymes

Question 8

What is characteristic of the Acanthamoeba Castellani infection in the eyes?

Answer 8

Stromal infiltrates in the shape of a complete or partial ring

Question 9

What is the immune response to Acanthamoeba Castellani?

Answer 9

Immune activation of neutrophils my lymphokines and opsonization of the amoeba by antibody promotes an ANTIBODY-DEPENDENT CELLULAR REACTION

Question 10

Is there partial or protective immunity following infection?

Answer 10

NO

Question 11

Symptoms of Acanthamoeba keratitis

Answer 11

Uveitis
optic neuritis
corneal keratitis

Granulomatous amoebic encephalitis

Acanthamoeba skin lesions

Question 12

Diagnosis of acanthamoebic keratitis or Acanthamoeba Castellani

Answer 12

Trichrome stained smear of tissue exudates demonstrating amoebas or starlike cysts

Question 13

Treatment

Answer 13

Propamidine