Amino Acids Continued Flashcards

1
Q

How many non polar amino acids are there?

A

9

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2
Q

How do you know an amino acid is non polar?

2

A

The R group is mostly made of hydrocarbons

May also feature a sulphur atom (methionine)

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3
Q

How many polar amino acids are there?

A

6

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4
Q

How do you know an amino acid is polar?

A

The R group contains an OH group, NH2 group or a HS group

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5
Q

How many acidic amino acids are there?

A

2

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6
Q

Name the two acidic amino acids.

A

Aspartic acid

Glutamic acid

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7
Q

How do you know if an amino acid is an acidic?

A

They will contain a COOH group

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8
Q

How do carboxyl groups of acidic amino acids act?

A

They act as nucleophiles

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9
Q

Acidic amino acids act as nucleophiles, what does this mean?

A

They can donate an electron pair to form a chemical bond

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10
Q

How many basic amino acids are there?

A

Three

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11
Q

How do you know if an amino acid is basic?

A

Positive charge on an NH3 + group

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12
Q

Describe an amino acid at a neutral pH

3

A

Carboxyl group is negatively charged

Amino group is positively charged

Zwitterion - no net charge

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13
Q

What is a zwitterion?

A

A molecule that contains an equal number of positively and negatively charged functional groups

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14
Q

What is ionisation?

A

The process where a molecule becomes positively or negatively charged by gaining/losing electrons

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15
Q

What do acids do?

A

They are proton donors

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16
Q

What do bases do?

A

They are proton acceptors

17
Q

What happens when an acid is added to water?

A

The pH level decreases

18
Q

What determines the acidity of a solution?

A

Its proton concentration

19
Q

How is pH expressed?

A

pH = -log to the base 10 [H+]

20
Q

How do strong acids differ from weak acids?

A

Strong acids completely dissociate in water while weak acids only partially dissociate

21
Q

What happens when an acid dissociates?

A

An acid releases a proton

22
Q

What happens when a weak acid dissociates?

A

A weak acid has two states

A dissociated state (A-)

An undissociated state (AH)

23
Q

What is the A-, AH dissociation equilibrium?

A

AH ->

24
Q

What is the equation for Ka?

A

([A-][H+]/[AH])

25
Q

What is the equation for pKa?

A

pKa = -log10 Ka

26
Q

What does a small pKA value mean?

A

The smaller the pKa, the stronger the acid