Amino Acids and Proteins Flashcards
What are amino acids?
The basic structural units (molecules) of proteins
What is the basic structure of an amino acid?
An amino group
A carboxylic group
A distinctive R (side) chain
All bonded to a carbon atom
The R-group side chain defines which amino acid is which
How are amino acids classified?
Amino acids can be classified as:
- Essential
- Conditionally essential
- Nonessential
These classifications directly relate to whether or not an amino acid is synthesised by the body or taken from an outside source.
What are the qualities of essential amino acids?
- They are not synthesised by the body
- Sourced from diet eg eggs, meats, legumes, and beans
What are the qualities of conditionally essential amino acids?
Produced / synthesised by the body, except in times of illness or stress
-Backbone sourced form carbohydrates and fats, nitrogen sourced from other proteins
What are the characteristics of nonessential amino acids?
Produced / synthesised entirely by the body
Backbone sourced form carbohydrates and fats, nitrogen sourced from other proteins
What are peptides and how are they classified?
Short strings of 2 - 50 amino acids
Classified by the number of amino acids in a chain
- Dipeptide (2 amino acids)
- Tripeptide (3 amino acids)
- Polypeptides (More than 10 amino acids)
What are peptide bonds?
Peptide bonds link amino acids to form polypeptide chains
What are mutations of genetic code and what kinds are there?
Malfunctioning or absence or protein
Point mutations = silent, nonsense, and missense
Frame shift mutations = insertion/deletion of a number of bases that is NOT a multiple of three
What is a protein?
Molecules that consist of more than 50 amino acids and one or more polypeptide chain
What are signs of amino acid deficiency?
Loss of muscle mass Blood sugar fluctuation Weight gain Fatigue Frequent infection Hair loss Anxiety Depression Slow wound healing
What is the central dogma / the flow of genetic information?
Replication of DNA
Transcription to mRNA
Translation to protein made of amino acids
What are the components of translation?
mRNA Amino acids tRNA (adpater molecules) Ribosomes (action stations) Enzymes and energy
How is RNA written to reflect a protein?
Initiation = start codon AUG Elongation = addition of amino acids by peptide bonds Termination = stop codon UAA, UAG, UGA
What are the four levels of protein stucture?
Primary structure
Secondary structure
Tertiary structure
Quaternary structure