Amino Acids Flashcards
1
Q
Glycine
A
- Achiral
- Neurotransmitter that makes channels permeable to Cl- (influx) which is inhibitory because it changes the membrane potential with a negative charge
- Aliphatic
- Hydrophobic
2
Q
Valine
A
- Isopropyl group
- Aliphatic
- Non-polar Hydrophobic
3
Q
Isoleucine
A
- 2 chiral centers
- Secbutyl group
- Isomer of Leucine
- Aliphatic
- Non-polar Hydrophobic
4
Q
Phenylalanine
A
- Benzyl group
- Aromatic stacking
- Aromatic
- Non-polar Hydrophobic
5
Q
Proline
A
- Imino Acid
- Forces kinks in proteins and when transitioning between structures
- Aliphatic
- Hydrophobic
6
Q
Threonine
A
- 2 chiral centers
- Aliphatic
- Polar Hydrophobic
7
Q
Alanine
A
- Can be converted into pyruvate when the metabolism is starving:
Pyruvate - CO2 –> can enter Krebs Cycle (Citric Acid Cycle)
Pyruvate can also be used in gluconeogensis to make sugars (glucose)
- Aliphatic
- Hydrophobic
8
Q
Leucine
A
- Isobutyl group
- Aliphatic
- Non-polar Hydrophobic
9
Q
Methionine
A
- Start Codon (AUG) on mRNA
- Thioether
- Aliphatic
- Non-polar Hydrophobic
10
Q
Tryptophan
A
- Largest side chain / bulky
- Indole group
- Resonance
- Aromatic Stacking
- Aromatic
- Non-polar Hydrophobic
11
Q
Serine
A
- Alcohol allows hydrogen bonding
- OH good for temporary bonding other groups
- Can (de)phosphorylate enzymes and proteins
- Aliphatic
- Polar Hydrophillic
12
Q
Cysteine
A
- Thiol group
- Can create tertiary and quaternary stuctures
- Aliphatic
- Hydrophobic (slightly polar)
13
Q
Cystine
A
2 Cysteine molecules are oxidized (lose hydrogens) to form a covalent disulfide bridge between them
14
Q
Tyrosine
A
- Phenol
- Ionizable side chain
- Resonance with a stable conjugate base
- Aromatic
- Polar Hydrophobic
15
Q
Asparagine
A
- Amide group
- 2 carbons in side chain
- Resonance (does not act as a base)
- Aliphatic
- Polar Hydrophillic
*Nitrogen storage for biosynthesis and a metabolism tie in through deamination (2x) will form an alpha-keto acid
Asparagine - NH2 –> Aspartate - NH3 –> Oxaloacetate (found in the Krebs cycle)