Amino Acid Trivia

Question 1

DM patients have elevated HbA1c. This is formed when blood glucose enters the erythrocytes and glycosylates the e-amino group of ___ residues in Hgb.

Answer 1

Lysine

Question 2

in Ames Test, the reversion of a Salmonella typhimurium mutant requiring ____, to the wild type is detected.

Answer 2

Histidine

Question 3

The iron in heme is linked to the ring nitrogen of this amino acid.

Answer 3

Histidine

Question 4

Propionate is a minor substrate for gluconeogenesis; which arises from beta oxidation of odd numbered fatty acids and oxidation of this amino acid.

Answer 4

Isoleucine

Question 5

Bile acids are conjugated with these two amino acids to form secondary bile acids

Answer 5

Glycine

Taurine

Question 6

Ceramide is synthesized using which amino acid

Answer 6

Serine

Question 7

Which amino acids can form acetyl Coa / acetoacetyl Coa?

Answer 7

A Lighter Lease (A LyTr LeIs)

Lysine
Tryptophan
Leucine
Isoleucine

Question 8

In the fasting state, these branched chain amino acids are used by skeletal muscles.

Answer 8

“Muscles LIVe fast”

Leucine
Isoleucine
Valine

Question 9

Creatine phosphate is derived from these three amino acids.

Answer 9

“Nice GAMs!”
(Gams = muscle = creatine phosphate. :O)

Glycine Arginine Methionine

Question 10

Purine synthesis requires these amino acids.

Answer 10

GAG

Glycine
Aspartate
Glutamine

Question 11

This amino acid carries nitrogen from peripheral tissues to the liver.

Answer 11

Alanine

Question 12

Precursor for niacin, serotonin and melatonin

Answer 12

Tryptophan

Question 13

Not an amino acid but is an IMINO acid

Answer 13

Proline

Question 14

Precursor for melanin, thyroxine, dopamine, norepinephrine and epinephrine

Answer 14

Tyrosine

MNEMONIC:
Pare, True Love Does Not Exist To Me.

Phenylalanine > Tyrosine > L-Dopa > Dopamine >
Norepinephrine > Epinephrine
Tyrosine, Melanin

Question 15

Phosphorylation site of enzyme modification; often linked to carbohydrate groups in glycoproteins

Answer 15

Serine

Question 16

Sites for O-linked glycosylation in Golgi apparatus

Answer 16

Serine

Threonine

Question 17

Site for N-linked glycosylation in Golgi apparatus

Answer 17

Asparagine

Question 18

Major carrier of nitrogen to the liver from peripheral tissues; “basurero”

Answer 18

Glutamine

Question 19

Precursor for glutathion

Answer 19

Glutamate

Question 20

Precursor for creatine, urea and nitric oxide

Answer 20

Arginine

Question 21

This amino acid is a weak base and has no charge.

Answer 21

Histidine

Question 22

Two amino acids that are commonly found in histones

Answer 22

Arginine

Lysine

Question 23

Precursor of histamine

Answer 23

Histidine

Question 24

Used in the diagnosis of folic acid deficiency

Answer 24

Histidine

Question 25

These amino acids are CONDITIONALLY non-essential.

Answer 25

Arginine - made in the body but in insufficient quantities | Histidine - may be recycled but should be consumed since it is not made at all

Question 26

HbF has this amino acid instead of His. This leads to higher affinity of HbF to O2.

Answer 26

Serine

Question 27

HbM has this amino acid instead of His. This leads to reduced O2 affinity.

Answer 27

Tyrosine

Question 28

In hemoglobin C disease, the hemoglobin variant has ___ in the 6th position instead of glutamate.

Answer 28

Lysine

Question 29

Collagen is rich in these two amino acids.

Answer 29

Proline (facilitates kinking) | Glycine (every third position)

Question 30

Cysteine while NOT nutritionally essential, is formed from __, which is essential.

Answer 30

Methionine

Question 31

Glycine is made from ___ while proline is synthesized from ___.

Answer 31

Glycine > Serine | Proline > Glutamate

Question 32

GABA uses this amino acid as a raw material.

Answer 32

Glutamate

Question 33

All the protein amino acids except ____ undergo transamination.

Answer 33

Lysine Threonine Proline Hydroxyproline

Question 34

Ketogenic amino acids

Answer 34

Leucine | Lysine

Question 35

Glucogenic + ketogenic amino acids

Answer 35

Phenylalanine (F) Tyrosine (Y) Tryptophan (W) Isoleucine (I) WI-FY

Question 36

Thioethanolamine of CoA and taurine is derived from this amino acid.

Answer 36

Cysteine

Question 37

Polyamines are derived from this amino acid.

Answer 37

Arginine

Question 38

No metabolic defects are associated with catabolism of the following amino acids

Answer 38

Asparagine Asparate Glutamine Glutamate

Question 39

These four amino acids share the same transporter in the kidney. Defect in the transporter leads to increased risk of stone formation.

Answer 39

Cystine Ornithine Arginine Lysine Mnemonic: COAL In cystinuria, transporter deficiency leads to increased formation of cystine stones.

Question 40

11-cis retinaldehyde reacts with ___ residue in opsin to form rhodopsin

Answer 40

Lysine

Question 41

Vitamin K is the cofactor for the carboxylation of ___ residues in post-synthetic modification of proteins.

Answer 41

Glutamate

Question 42

Pantothenic acid combines with ___ to form the pantotheine moiety in many enzymes.

Answer 42

Cysteine

Question 43

A1-antitrypsin has a particular ___ involved in binding to proteases which is oxidized (and inactivated) by smoking.

Answer 43

Methionine 358