Amines Flashcards
What do you call amines if its a substituent?
Amino
Why as Mr increase, BP increase?
Size and polarisability of e cloud increases, extent of intermolecular instantaneous dipole-induced-dipole attraction increases
Why BP of amines follow 1°>2°>3°?
Hydrogen bonds in 1°and2° stronger than idid in 3°, between 1 and 2, more alkyl groups in 2 results in more stearic effect, availability of lp of n decreases for intermolecular hydro bonds
Why BP of amines<alcohol
N-H less polar than OH, weaker hydro
What affects basicity of amines?
Electron donating/withdrawing groups increasing/decreasing electron density of lp , or benzene rings delocalising lp
Why e sub on phenylalamine no need catalyst or heat?
Lp of N delocalise, increasing e density of the ring so e.g br onto the ring is easier, also activating so 2,4
Why 3°amines bp<1 and 2?
No intermolecular hydro bond
Why amides neutral unlike amines?
Lp of n delocalise to adjacent c=o, cannot accept H+
What do you call an amine that accepted a H+?
Amine salt
Why amino acids exists as crystalline solids with high mp
Dipolar results in electrostatic forces of attraction
Why amino acids soluble?
Ion dipole interactions with water molecules results in release of energy, causing detachment of skittering from the crystal lattice for solvation
