American trypanosoma Flashcards
synonym
Chagas disease
Etio
T. Cruzi
Demography.CentralandSouthAmerica
Transmission
Transmission. T.cruzi deposited in feces of reduviid bugs onto the skin;enters host via breaks in skin
(excoriations),mucous membranes,or conjunctivae.Can also be transmitted by transfusion of blood from inected persons,by organ transplantation,and from mother to fetus.
■ Dissemination. Via lymphatics and bloodstream to muscles.
manif
INOCULATION SITECHAGOMA An indurated area o erythemaandswelling,attheportalo entry, occurring7to14daysa erinoculation.May be accompanied by local lymphadenopathy. Parasites located within leukocytes and cells o subcutaneous tissues. T ese initial local signs are ollowedbymalaise, ever,anorexia,and edema o the ace and lower extremities. ROMAÑASIGN Unilateralpainlessedemao palpebrae and periocular tissues. Occurs when conjunctivaistheportalo entry.Classicfnd- ing in acute A .
Edema o ace and lower extremities. TRYPANOSOMIDES Morbilli orm, urticari orm, or erythematopolymorphic eruptions. HEMATOGENICORMETASTATICCHAGOMAS Nodule(s) caused by dissemination o
in ection. Hard, pain ul, wine-colored nodules; rarelyso enorulcerate.
SYSTEMICFINDINGS Generalized lymphade- nopathy.Hepatosplenomegaly.Severemyocar- ditismayoccur;mostdeathsresult romheart
ailure.
INDETERMINATE/ASYMPTOMATICPHASE Charac- terized by subpatent parasitemia, detectable antibodiestoT.cruzi,absenceo associated signs and symptoms. SYMPTOMATICCHRONICINFECTION Maytake several decades to develop. Symptomatic disease:Heart(rhythmdisturbances,cardio- myopathy, and thromboembolism), mega- esophagus, megacolon, and peripheral nervous system disease.
COURSE Most in ected persons remain so or
li e. Heart and GI involvement associated with serious morbidity and mortality.
What sign is this.
Unilateralpainless edema of palpebrae and periocular tissues. Occurs when conjunctivaistheportalo entry
Romana sign
